Abstract
Heterochromatic modulation photometry (HMP) was used to look for evidence of inhomogeneities in foveal cone ratios for heterozygous carriers of X-linked congenital color defects. Critical flicker frequency (CFF) was measured both as a function of amplitude for monochromatic flicker and as a function of red/green luminance ratio for heterochromatic flicker. The heterochromatic flicker data were fit with a template derived from a linear sum of cone responses. For normal trichromats, males with X-linked congenital color defects, and carriers of deutan defects, the heterochromatic flicker data were fit well by the template and had a distinct minimum near the photometric match. The minimum was less distinct for heterozygous carriers of protan defects. This finding is consistent with Lyonization of the genes controlling photopigment production, and is evidence of inhomogeneities in foveal cone ratios for carriers of protan defects.
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Swanson, W.H. (1991). Heterochromatic modulation photometry in heterozygous carriers of congenital color defects. In: Drum, B., Moreland, J.D., Serra, A. (eds) Colour Vision Deficiencies X. Documenta Ophthalmologica Proceedings Series, vol 54. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3774-4_54
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DOI: https://doi.org/10.1007/978-94-011-3774-4_54
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