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Side-Effects of Anti-Inflammatory Drugs

Part One Clinical and Epidemiological Aspects

  • Book
  • © 1987

Overview

Editors:
  1. K. D. Rainsford

    1. Department of Pharmacology, University of Cambridge, Cambridge, UK
      Strangeways Research Laboratory, Cambridge, UK

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  2. G. P. Velo

    1. Institute of Pharmacology, University of Verona, Verona, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Inflammation and Drug Therapy Series (IDTH, volume 1)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xxv
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  2. Clinical and Epidemiological Aspects

    1. Front Matter

      Pages 1-1
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    2. Introduction and historical aspects of the side-effects of anti-inflammatory analgesic drugs

      • K. D. Rainsford
      Pages 3-26

    3. Epidemiology in the United Kingdom of adverse drug reactions from non-steroidal anti-inflammatory drugs

      • J. C. P. Weber
      Pages 27-35

    4. Assessment of adverse reactions to NSAIDs: pre- and post- marketing

      • E. F. Barker
      Pages 37-46

    5. Incidence of serious side-effects from non-steroidal anti-inflammatory drugs (NSAIDs) in the USA

      • H. Jick
      Pages 47-53

    6. Trends and patterns in adverse drug reactions to non-steroidal anti-inflammatory drugs reported in Sweden

      • B. E. Wiholm, M. Myrhed, E. Ekman
      Pages 55-72

    7. Rare adverse reactions to non-steroidal anti-inflammatory drugs

      • W. M. O’Brien
      Pages 73-98

    8. Pyrazoione-induced agranulocytosis: an epidemiological evaluation

      • Micha Levy
      Pages 99-104

    9. Potential biases influencing interpretation of data from worldwide spontaneous ADR reports

      • A. J. Gordon, R. Sachs
      Pages 105-110

    10. Prescription-event monitoring of five non-steroidal anti-inflammatory drugs

      • W. H. W. Inman, N. S. B. Rawson
      Pages 111-124

    11. Side-effects of non-steroidal anti-inflammatory drugs in children with juvenile rheumatoid arthritis

      • T. K. Kvien, H. M. Høyeraal, B. Sandstad, E. KÃ¥ss
      Pages 125-135

    12. Non-steroidal anti-inflammatories: outpatient audit of patient preferences and side-effects in different diseases

      • N. L. Cox, S. M. Doherty
      Pages 137-150

    13. Non-steroidal anti-inflammatories in the elderly

      • P. P. Lamy
      Pages 151-172

    14. Ibuprofen overdose — the first year following over-the-counter release

      • S. Perry, P. Streete, G. N. Volans
      Pages 173-175

  3. Drug Interactions and Drug Metabolism

    1. Front Matter

      Pages 177-177
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    2. Drug interactions between the anti-inflammatory drugs and with other agents

      • P. F. D’Arcy, J. C. McElnay
      Pages 179-193

    3. Interaction between non-steroidal anti-inflammatory drugs and angiotensin-converting enzyme inhibitors in man

      • G. P. Velo, P. Minuz, E. Arosio, M. G. Capuzzo, G. Covi, A. Lechi
      Pages 195-201

    4. Responders and non-responders to NSAI drug interactions — a neglected problem?

      • F. Sörgel, R. Koob, M. Hemmerlein, J. Braun, E. Lang
      Pages 203-215

    5. Biological implications of the metabolic chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs

      • J. Caldwell, A. J. Hutt
      Pages 217-228
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Keywords

About this book

These two volumes contain the proceedings of a 3 day international meeting held at the University of Cambidge and Queens' College Cambridge from 31st July to 2nd August 1985 on the Side-Effects of Anti-Inflammatory Analgesic Drugs. The first meeting was held in Verona, (Italy) in 1982 and the organisers felt that, with a number of recent developments including the withdrawal of a num­ ber of new anti-inflammatory drugs, and concern being expressed in the lay and specialist medical press and other media about the safety of these drugs, that it was appropriate to have a second such meeting. The meeting was attended by some 300 delegates and the dis­ cussion focussed most intently on the recent issues, e. g. the value of adverse drug reaction reporting of the non-steroidal anti­ inflammatory (NSAI) drugs, certain side-effects associated with particular NSAI drugs, the predictive value of animal models etc. Organising a meeting de novo without outside help would not have been possible without the immensely valuable help given en­ thusiastically by people and financial assistance given most generously by those pharmaceutical companies listed below. These financial contributions were given despite current economic dif­ ficulties and moves to restrict the proportion of profits towards educational activities.

Editors and Affiliations

  • Department of Pharmacology, University of Cambridge, Cambridge, UK

    K. D. Rainsford

  • Strangeways Research Laboratory, Cambridge, UK

    K. D. Rainsford

  • Institute of Pharmacology, University of Verona, Verona, Italy

    G. P. Velo

Bibliographic Information

  • Book Title: Side-Effects of Anti-Inflammatory Drugs

  • Book Subtitle: Part One Clinical and Epidemiological Aspects

  • Editors: K. D. Rainsford, G. P. Velo

  • Series Title: Inflammation and Drug Therapy Series

  • DOI: https://doi.org/10.1007/978-94-010-9772-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1987

  • Softcover ISBN: 978-94-010-9774-1Published: 16 April 2012

  • eBook ISBN: 978-94-010-9772-7Published: 06 December 2012

  • Series ISSN: 0923-9405

  • Edition Number: 1

  • Number of Pages: 352

  • Topics: Pharmacology/Toxicology, Rheumatology

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