Abstract
In this study a number of experimental and computational methods were employed to examine the effect of multiply scattered light detection on image quality and penetration depth of optical coherence microscopy (OCM) in turbid media. Measurements of the OCM resolution at different optical depths in the scattering media reveal that detection of multiply scattered light causes significant degradation of the lateral and axial resolution and that the deterioration effect is dependent on the turbid media scattering anisotropy and the numerical aperture (NA) of the imaging objective.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
J. Powley, Handbook of biological confocal microscopy (Plenum Press, New York, 1995).
R. Webb, Rep. Prog. Phys. 59, 427–471 (1996).
M. Rajadhyaksha, Appl. Opt. 38, 2105–2115 (1999).
D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito and J. G. Fujimoto, Science 254, 1178–1181 (1991).
J. Schmitt, A. Knuttel, A. H. Gandjbakhche and R. F. Bonner, Proc. SPIE 1889, 197–211 (1993).
B. Bouma, Opt.Lett. 20, 1486–1488 (1995).
A. Yodh and B. Chance, Phys. Today, 48, 34–40 (1995).
S. Arridge, Inverse Problems, 15, R41–R94 (1999).
M. Kempe, A. Z. Genack, W. R. Dorn and P. Dora, J. Opt. Soc. Am. A 14, 216–223 (1997).
M. Kempe, J. Opt. Soc. Am. A 13, 46–52 (1996).
M. Yadlowsky, J. M. Schmitt and R. F. Bonner, Appl. Opt. 34, 5699–5707 (1995).
J. Izatt, M. R. Hee, G. M. Owen, E. A. Swanson and J. G. Fujimoto, Opt. Lett. 19, 590–592 (1994).
Y. Pan, R. Birngruber and R. Engelhardt, Appl. Opt. 36, 2979–2983 (1997).
D. A. Boas, K. K. Bizheva and A. M. Siegel, Opt. Lett. 23, (1998).
K. Bizheva, D. A. Boas, Phys. Rev. E, 58, 7664–7667 (1998).
P.J. Berne and R. Pecora, (Wiley, New York, 1976).
R. Pecora, (Plenum Press, New York, 1985).
D. J. Pine, D. A. Weitz, P. M. Chaikin and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134–1137 (1988).
G. Maret and P. E. Wolf, Z. Phys. B 65, 409–413 (1987).
D. Durian, Phys. Rev. E 51, 3350–3358 (1995).
P. Kaplan, M. H. Kao, A. G. Yodh and D. J. Pine, Appl. Opt. 32, 3828–3836 (1994).
A. Yodh, P. D. Kaplan and D. J. Pine, Phys. Rev. B 42, 4744–4747 (1990).
S. L. Wang, S. L. Jacques, and L. Zheng, Computer Methods and Programs in Biomedicine 47, 131–146 (1995).
A.K. Dunn, C. Smithpeter, A.J. Welch and R. Richards-Kortum, Appl. Opt. 35, 3441–3444 (1996).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Bizheva, K.K., Siegel, A.M., Dunn, A.K., Boas, D.A. (2001). Detection of Multiply Scattered Light in Optical Coherence Microscopy. In: Sebbah, P. (eds) Waves and Imaging through Complex Media. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0975-1_15
Download citation
DOI: https://doi.org/10.1007/978-94-010-0975-1_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-0372-1
Online ISBN: 978-94-010-0975-1
eBook Packages: Springer Book Archive