Abstract
Our increased dependence on cultured as opposed to wild stocks of fish as a dietary source of protein has necessitated steps to control reproduction of fish as many species fail to ovulate under captive conditions. Some fish species exhibit a protracted breeding season and it is desirable to control the timing and synchrony of breeding to increase the efficiency of aquaculture operations. Historically, fish culturists have relied upon the administration of fish pituitary extracts, or in certain cases mammalian gonadotropin preparations to induce ovulation [1]. More recently, efforts have been made to substitute the use of LHRH peptide hormones for the more expensive pituitary hormone preparations. Since the first demonstration that LHRH stimulates gonadotropin (GtH) release from carp pituitaries in vitro [2], there have been numerous reports showing that LHRH-and LHRH analogs stimulate GtH release in a variety of teleosts [3–5]. To date, the use of these compounds to regulate fish reproduction has met with varied success. In recent studies it has been demonstrated that distinct forms of LHRH are present in submammalian vertebrates [6] and these findings have opened new avenues of research investigating the use of fish, bird and mammalian LHRH analogs for the hormonal control of reproduction of fish in aquaculture [7–8].
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References
Donaldson, E.M. and Hunter, G.A. Induced final maturation, ovulation and spermiation in cultured fish. In “Fish Physiology”, Vol. IXB, W.S. Hoar, D.J. Randall and E.M. Donaldson (Eds.), Academic Press, New York, 1983, p. 351.
Breton, B., Weil, C., Jalabert, B. and Billard, R. Activite reciproque des facteurs hypothalamiques de belier (Ovis aries) et de poissons teleosteen sur la secretion in vitro des hormones gonadotropes G-HG et LH respectivement par les hypophyses de carpe et de belier. C.R. Acad. Sci. Ser. D., 274, 2530 (1972).
Crim, L.W. Actions of LHRH and its analogs in lower vertebrates. In “LHRH and Its Analogs: Contraceptive and Therapeutic Applications”, B.H. Vickery, J.J. Nestor Jr. and E.S.E. Hafez (Eds.), MTP Press Ltd., Lancaster, 1984, p. 377.
Peter, R.E. Evolution of neurohormonal regulation of reproduction in lower vertebrates. Amer. Zool., 23, 685 (1983).
Peter, R.E. The brain and neurohormones in teleost reproduction. In “Fish Physiology”, Vol. IXA, W.S. Hoar, D.J. Randall and E.M. Donaldson (Eds.), Academic Press, New York, 1983, p. 97.
Sherwood, N.M. Evolution of a neuropeptide family: Gonadotropin-releasing hormone. Amer. Zool. (In Press).
Peter, R.E., Nahorniak, C.S., Sokolowska, M., Chang, J.P., Rivier, J.E., Vale, W.W., King, J.A. and Millar, R.P. Structure-activity relationships of mammalian, chicken, and salmon gonadotropin releasing hormones in vivo in goldfish. Gen. Comp. Endocrinol., 58, 231 (1985).
Crim, L.W. A variety of synthetic LHRH peptides stimulate gonadotropic hormone secretion in rainbow trout and the landlocked Atlantic salmon. In The Journal of Steroid Biochemistry 20, 1390. Abstract A51 (1984).
Stacey, N.E., Cook, A.F. and Peter, R.E. Ovulatory surge of gonadotropin in the goldfish, Carassius auratus. Gen. Comp. Endocrinol., 37, 246 (1979).
Stacey, N.E., Cook, A.F. and Peter, R.E. Spontaneous and gonadotropin-induced ovulation in the goldfish, Carassius auratus L.: Effects of external factors. J. Fish. Biol. 15, 349 (1979).
Lin, H.R., Van Der Kraak, G., Liang, J.Y., Peng, C., Li, G.Y., Lu, L.Z., Zhou, X.J., Chang, M.L. and Peter, R.E. The effects of LHRH analogue and drugs which block the effects of dopamine on gonadotropin secretion and ovulation in fish cultured in China. In “Proceedings of the International Symposium on the Aquaculture of Carp and Related Species”, R. Billard (Ed.), I.N.R.A. Publications, Versailles, France, 1986 (in press).
Anon (Cooperative Team for Hormonal Application in Pisciculture). A new highly effective ovulating agent for fish reproduction. Practical application of LH-RH analogue for the induction of spawning of farm fishes. Sci. Sinica., 20, 469 (1977).
Fukien-Kiangsu-Chekiang-Shanghai Cooperative Group. A further investigation on the stimulatory effect of a synthetic analogue of hypothalamic luteinizing hormone releasing hormone (LRH-A) on spawning in “domestic fishes”. Acta Biochim. Biophys. Sin., 9, 15 (1977).
Jiang, R., Huang, S. and Zhao, W. Changes of serum gonadotropin levels before and behind induced spawning in grass carp and silver carp. J. Fish. China, 4, 129 (1980).
Chang, J.P. and Peter, R.E. Effects of pimozide and des Gly10, [D-Ala6] luteinizing hormone-releasing hormone ethylamide on serum gonadotropin concentrations, germinal vesicle migration, and ovulation in female goldfish, Carassius auratus. Gen. Comp. Endocrinol., 52, 30 (1983).
Chang, J.P., Peter, R.E., Nahorniak, C.S. and Sokolowska, M. Effects of catecholaminergic agonists and antagonists on serum gonadotropin concentrations and ovulation in goldfish: Evidence for specificity of dopamine inhibition of gonadotropin secretion. Gen. Comp. Endocrinol., 55, 351 (1984).
Sokolowska, M., Peter, R.E., Nahorniak, C.S., Pan, C.H., Chang, J.P., Crim, L.W. and Weil, C. Induction of ovulation in goldfish, Carassius auratus, by pimozide and analogues of LH-RH. Aquaculture, 36, 71 (1984).
Sokolowska, M., Peter, R.E., Nahorniak, C.S. and Chang, J.P. Seasonal effects of pimozide and des Gly10 [D-Ala6] LH-RH ethylamide on gonadotropin secretion in goldfish. Gen. Comp. Endocrinol., 57, 472 (1985).
Sokolowska, M., Peter, R.E. and Nahorniak, C.S. The effects of different doses of pimozide and [D-Ala6, Pro9-N ethylamide]-LHRH (LHRH-A) on gonadotropin release and ovulation in female goldfish. Can. J. Zool., 63, 1252 (1985).
Weil, C., Fostier, A., Horvath, L., Marlot, S. and Berscenyi, M. Profiles of plasma gonadotropin and 17β-estradiol in the common carp, Cyprinus carpio L., as related to spawning induced by hypophysation or LH-RH treatment. Reprod. Nutr. Dev., 20, 1041 (1980).
Billard, R., Alagarswami, K., Peter, R.E. and Breton, B. Potentialisation par le pimozide des effets du LHRH-A sur la secretion gonadotrope hypohysaire, l’ovulation et la spermiation chez la Carpe commune (Cyprinus carpio). C.R. Acad. Sci. Paris, Serie III, 296, 181 (1983).
Billard, R., Bieniarz, K., Peter, R.E., Sokolowska, M., Weil, C. and Crim, L.W. Effects of LHRH and LHRH-A on plasma GtH levels and maturation/ovulation in the common carp, Cyprinus carpio, kept under various environmental conditions. Aquaculture, 41, 245 (1984).
Lin, H.R., Liang, J.Y., Peng, C., Li, G.Y., Liu, L.Z., Zhou, X.J., Chang, M.L., Van Der Kraak, G. and Peter, R.E. Pimozide and reserpine potentiate the effects of LHRH-A on gonadotropin secretion and ovulation in cultivated fishes in China. In “Proceedings of the Asian Symposium on Freshwater Fish Culture”, China Society of Fisheries. The Academic Publisher of China, Beijing, P.R. China (1986).
Kaul, M. and Rishi, K.K. Induced spawning of the indian major carp, Cirrhina mrigala (Ham.), with LHRH analogue or pimozide. Aquaculture 54, 45 (1986).
Kouril, J., Dart, T., Hamackova, J. and Flegel, M. Induced ovulation in tench (Tinca tinca L.) by various LHRH synthetic analogues: effect of site of administration and temperature. Aquaculture 54, 37 (1986).
Chang, J.P. and Peter, R.E. Effects of dopamine on gonadotropin release in female goldfish, Carassius auratus. Neuro-endocrinology, 36, 351 (1983).
Chang, J.P., Peter, R.E. and Crim, L.W. Effects of dopamine and apomorphine on gonadotropin release from the transplanted pars distalis in goldfish. Gen. Comp. Endocrinol., 55, 347 (1984).
Chang, J.P., MacKenzie, D.S., Gould, D.R. and Peter, R.E. Effects of dopamine and norepinephrine on in vitro spontaneous and gonadotropin-releasing hormone-induced gonadotropin release by dispersed cells or fragments of the goldfish pituitary. Life Sci., 15, 2027 (1984).
Peter, R.E., Chang, J.P., Nahorniak, C.S., Omeljaniuk, R.J., Sokolowska, M., Shih, S.H. and Billard, R. Interactions of catecholamines and GnRH in regulation of gonadotropin secretion in teleost fish. Rec. Progr. Horm. Res., 42, 513 (1986).
Peter, R.E. Structure-activity studies on gonadotropin-releasing hormone in teleosts, amphibians, reptiles, birds and mammals. In “Comparative Endocrinology: Developments and Directions”, C.L. Ralph (Ed.), Alan R. Liss, New York, 1986, p. 75.
Donaldson, E.M., Hunter, G.A., Van Der Kraak, G. and Dye, H.M. Application of LH-RH and LH-RH analogues to the induced final maturation and ovulation of coho salmon (Oncorhynchus kisutch). In “Proceedings of the International Symposium on Reproductive Physiology of Fish”, C.J.J. Richter and H.J.Th. Goos (Eds.), Pudoc, Wageningen, The Netherlands, 1982, pp. 177–180.
Van Der Kraak, G., Dye, H.M., Donaldson, E.M. and Hunter, G.A. Plasma gonadotropin, 17β -estradiol and 17β 20α dihydroxy-4-pregnen-3-one levels during luteinizing hormone releasing hormone analogue and gonadotropin induced ovulation in coho salmon (Oncorhynchus kisutch). Can. J. Zool., 63, 824 (1985).
Crim, L.W., Evans, D.M. and Vickery, B.H. Manipulation of the seasonal reproductive cycle of the landlocked Atlantic salmon (Salmo salar) by LHRH analogues administered at various stages of gonadal development. Can. J. Fish. Aquat. Sci., 40, 61 (1983).
Crim, L.W., Sutterlin, A.M., Evans, D.M. and Weil, C. Accelerated ovulation by pelleted LHRH analogue treatment of spring-spawning rainbow trout (Salmo gairdneri) held at low temperature. Aquaculture, 35, 299 (1983).
Crim, L.W. and Glebe, B.D. Advancement and synchrony of ovulation in Atlantic salmon with pelleted LHRH analog. Aqua-culture, 43, 47 (1984).
Crim, L.W., Glebe, B.D. and Scott, A.P. The influence of LHRH analog on oocyte development and spawning in female Atlantic salmon, Salmo salar. Aquaculture (in press).
Scott, A.P., Sumpter, J.P. and Hardiman, P.A. Hormone changes during ovulation in the rainbow trout (Salmo gairdneri Richardson). Gen. Comp. Endocrinol., 49, 128 (1983).
Weil, C. and Crim, L.W. Administration of LHRH analogues in various ways: effect on the advancement of spermiation in prespawning landlocked salmon, Salmo salar. Aquaculture, 35, 103 (1983).
Fitzpatrick, M.S., Suzumoto, B.K. and Schreck, C.B. Luteinizing hormone-releasing hormone analogue induces precocious ovulation in adult coho salmon (Oncorhynchus kisutch). Aquaculture, 43, 67 (1984).
Sower, S.A., Iwamoto, R.N., Dickhoff, W.W. and Gorbman, A. Ovulatory and steroidal responses in coho salmon and steelhead trout following administration of salmon gonadotropin and D-Ala6, des Gly10 gonadotropin-releasing hormone ethylamide (GnRHa). Aquaculture, 43, 35 (1984).
Billard, R., Reinaud, P., Hollenbecq, M.G. and Breton, B. Advancement and synchronisation of spawning in Salmo gairdneri and S. trutta following administration of LRH-A combined or not with pimozide. Aquaculture, 43, 57 (1984).
Van Der Kraak, G., Donaldson, E.M. and Chang, J.P. Dopamine involvement in the regulation of gonadotropin secretion in coho salmon. Can. J. Zool. 64, 1245 (1986).
Schreck, C.B. and Fitzpatrick, M. Induced maturation in salmon. In “Research Information Bulletin” No. 83–51, U.S. Fish & Wildlife Service.
Lacanilao, F. and Marte, C.L. Sexual maturation of milkfish in floating cages. Asian Aquaculture, 3, 4 (1980).
Kuo, C-M. A review of induced breeding of milkfish. In “Reproduction and Culture of Milkfish”, C-S. Lee and I-C. Liao (Eds.), Published by The Oceanic Institute and Tungkang Marine Laboratory, Hawaii, 1985, p. 57.
Lee, C.-S., Tamaru, C.S., Banno, J.E., Kelley, C.D., Bocek, A. and Wyban, J.A. Induced maturation and spawning of milkfish, Chanos chanos Forsskal, by hormone implantation. Aquaculture, 52, 199 (1986).
Crim, L.W. and Evans, D.M. The influence of testosterone and/ or LHRH analogue on precocious sexual development in the juvenile rainbow trout. Biol. Reprod. 29, 137 (1983).
Marte, C.L., Sherwood, N.M., Crim, L.W. and Harvey, B. Induced spawning of maturing milkfish (Chanos chanos, Forskal) with gonadotropin-releasing hormone (GnRH) analogues administered in various ways. Aquaculture (in press).
Harvey, B., Nacario, J., Crim, L.W., Juario, J.V. and Marte, C.L. Induced spawning of sea bass, Lates calcarifer and rabbitfish, Siganus guttatus after implantation of pelleted LHRH analogue. Aquaculture, 47, 53 (1985).
Lin, H.R., Peng, C., Lu, L.Z., Zhou, X.J., Van Der Kraak, G. and Peter, R.E. Induction of ovulation in the loach (Paramisgurnus dabryanus) using pimozide and [D-Ala6, Pro9- N-ethylamide]-LHRH. Aquaculture, 46, 333 (1985).
Lin, H.R., Peng, C., Van Der Kraak, G., Peter, R.E. and Breton, B. Effects of [D-Ala6, Pro9-NHEt]LHRH and catecholaminergic drugs on gonadotropin secretion and ovulation in the Chinese loach (Paramisgurnus dabryanus). Gen. Comp. Endocrinol, (in press).
De Leeuw, R., Goos, H.J.Th., Richter, C.J.J. and Edig, E.H. Pimozide-LHRHa-induced breeding of the African catfish, Clarias gasiepinus (Burchell). Aquaculture, 44, 295 (1985).
De Leeuw, R., Resink, J.W., Rooyakkers, E.J.M. and Goos, H.J.Th. Pimozide modulates the luteinizing hormone-releasing hormone effect on gonadotropin release in the African catfish, Clarias lazera. Gen. Comp. Endocrinol., 58, 120 (1985).
Pankhurst, N.W., Van Der Kraak, G. and Peter, R.E. Effects of human chorionic gonadotropin, Des-Gly10 (D-Ala6) LHRH-ethylamide and pimozide on oocyte final maturation, ovulation and levels of plasma sex steroids in the walleye (Stizostedion vitreum). Fish Physiol. Biochem., 1, 45 (1986).
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Crim, L.W., Peter, R.E., Van Der Kraak, G. (1987). The Use of LHRH Analogs in Aquaculture. In: Vickery, B.H., Nestor, J.J. (eds) LHRH and Its Analogs. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3229-6_32
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DOI: https://doi.org/10.1007/978-94-009-3229-6_32
Publisher Name: Springer, Dordrecht
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