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ß-barrel Channel Proteins as Tools in Nanotechnology

Biology, Basic Science and Advanced Applications

  • Book
  • © 2014

Overview

Authors:
  1. Marco Fioroni

    1. Sustainable Momentum, Aachen, Germany

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  2. Tamara Dworeck

    1. Department of Biology, RWTH Aachen University, Aachen, Germany

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  3. Francisco Rodriguez-Ropero

    1. Center of Smart Interfaces, Technische Universität Darmstadt, Darmstadt, Germany

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  • Gives a comprehensible report on how to use beta-barrel membrane proteins as nano-material components (including all involved steps)
  • Is useful for both experimentalists and theoreticians that want to expand their knowledge toward the rapidly expanding field of membrane protein based bio-nanotechnology
  • Includes a chapter with "wet-lab" information on the beta-barrel membrane protein production (including trouble shootings and suggestions)

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 794)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Introduction

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 1-6

  3. Biology

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 7-40

  4. Biophysical Characterization

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 41-67

  5. Theoretical Considerations and Computational Tools

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 69-93

  6. Biotechnology

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 95-140

  7. Technological Applications

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 141-163

  8. Final Considerations

    • Marco Fioroni, Tamara Dworeck, Francisco Rodríguez-Ropero
    Pages 165-166

  9. Back Matter

    Pages 167-168
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Keywords

About this book

ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

Reviews

From the reviews:

“This book is a good introduction to the problems of OMPs and their use as nanotechnology material. Because the book considers the aspects of concept design, theoretical considerations, production traps, and the biological characterization of OMP, it should be useful for graduate students and researchers in the field of nanotechnology.” (Alexander Tzanov, Computing Reviews, March, 2014)

Authors and Affiliations

  • Sustainable Momentum, Aachen, Germany

    Marco Fioroni

  • Department of Biology, RWTH Aachen University, Aachen, Germany

    Tamara Dworeck

  • Center of Smart Interfaces, Technische Universität Darmstadt, Darmstadt, Germany

    Francisco Rodriguez-Ropero

Bibliographic Information

  • Book Title: ß-barrel Channel Proteins as Tools in Nanotechnology

  • Book Subtitle: Biology, Basic Science and Advanced Applications

  • Authors: Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-94-007-7429-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 2014

  • Hardcover ISBN: 978-94-007-7428-5Published: 13 November 2013

  • Softcover ISBN: 978-94-024-0756-3Published: 23 August 2016

  • eBook ISBN: 978-94-007-7429-2Published: 04 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 168

  • Number of Illustrations: 16 b/w illustrations, 29 illustrations in colour

  • Topics: Protein Structure, Gene Expression, Biotechnology, Computational Biology/Bioinformatics

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