Abstract
Caffeine (1,3,7-trimethylxanthine) is a naturally occurring, commercially important alkaloid. It is an active psychostimulant which increases alertness and sustains concentration by overcoming fatigue. This makes caffeine one of the most widely consumed dietary chemicals, with the global consumption ranging from 80 to 400 mg caffeine per person per day. During coffee processing, various byproducts like pulp water, husk etc. containing appreciably high content of caffeine are generated and are discarded as wastes. Pulp, husk and other waste products from coffee and tea industries increase toxicity of surrounding landmass due to their caffeine content resulting in soil infertility. Effluents are often discharged into water bodies, contaminating drinking and surface water with caffeine and affecting the saprophytic organisms involved in essential biotransformation in the environment. Decaffeination therefore becomes an important step in coffee processing. In this aspect, microbial cells and enzymes, which are biological and non toxic, have been found to be more beneficial than conventional techniques using chemicals and energy. Several microbial strains and enzyme systems such as N-demethylases and caffeine oxidases have been discovered over the last two decades which serve are potential candidates for development of biodecaffeination techniques. The rarity of strains and the unstable nature of caffeine degrading enzymes are some of the challenges with scope for research and development in the area of biodecaffeination.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
M.R. Adams, J. Dougan, Trop. Sci. 123, 178–196 (1981)
Y. Asano, T. Komeda, H. Yamada, Biosci. Biotechnol. Biochem. 57, 1286–1289 (1993)
Y. Asano, T. Komeda, H. Yamada, Biosci. Biotechnol. Biochem. 58, 2303–2304 (1994)
H. Ashihara, A. Crozier, Trends Plant Sci. 6, 407–413 (2001)
H. Ashihara, A.M. Monteiro, F.M. Gillies, A. Crozier, Plant Physiol. 111, 747–753 (1996)
S. Avallone, B. Guyot, J.M. Brillouet, E. Olguin, J.P. Guiraud, Curr. Microbiol. 42, 252–256 (2001)
R. Blecher, F. Lingens, Hoppe Seylers Z. Physiol. Chem. 358, 807–817 (1977)
W.H. Bradshaw, H.A. Barker, J. Biol. Chem. 235, 3620–3629 (1960)
D. Brand, A. Pandey, S. Roussos, C.R. Soccol, Enzyme Microb. Technol. 27, 127–133 (2000)
D. Brand, A. Pandey, J.A. Rodriguez-Leon, S. Roussos, I. Brand, C.R. Soccol, Biotechnol. Prog. 17, 1065–1070 (2001)
D. Brand, A. Pandey, J.A. Rodriguez-Leon, S. Roussos, I. Brand, C.R. Soccol, Appl. Biochem. Biotechnol. 102–103, 169–177 (2002)
R.C. Bray, in The Enzymes, ed. by P.D. Boyer, H. Lardy, K. Myrback (Academic, New York, 1965), pp. 533–556
R. Bressani, in Coffee Pulp: Composition, Technology, and Utilization, ed. by J.E. Brahan, R. Bressani (Institute of Nutrition of Central America and Panama, Guatemala City, 1987), pp. 83–88
I.J. Buerge, T. Poiger, M.D. Muller, H.R. Buser, Environ. Sci. Technol. 37, 691–700 (2003)
C. Campa, S. Doulbeau, S. Dussert, S. Hamon, M. Noirot, Food Chem. 79, 419–424 (2004)
J.W. Daly, B.B. Fredholm, Drug Alcohol Depend. 51, 199–206 (1998)
J.R. Feldman, S.N. Katz, in Encyclopedia of Chemical Processing and Design, ed. by J.J. McKetta, vol. 5 (Marcel Dekker Inc, New York, 1977), pp. 424–440
J. Friedman, G.R. Waller, J. Chem. Ecol. 9, 1099–1106 (1983)
S.T. Glassmeyer, E.T. Furlong, D.W. Kolpin, J.D. Cahill, S.D. Zaugg, S.L. Werner, M.T. Meyer, D.D. Kryak, Environ. Sci. Technol. 39, 5157–5169 (2005)
M. Glück, F. Lingens, Appl. Microbiol. Biotechnol. 28, 59–62 (1988)
S. Gokulakrishnan, K. Chandraraj, S.N. Gummadi, Enzyme Microb. Technol. 37, 225–232 (2005)
S.N. Gummadi, D. Santhosh, Cent. Eur. J. Biol. 4, 1–11 (2006)
M. Hakil, S. Denis, G.V. Gonzalez, C. Augur, Enzyme Microb. Technol. 22, 355–359 (1998)
M. Hakil, F. Voisinet, G.V. González, C. Augur, Process Biochem. 35, 103–109 (1999)
W. Hohnloser, B. Osswalt, F. Lingens, Hoppe seyler’s Z. Physiol. Chem. 361, 1763–1766 (1980)
A. Kato, A. Crozier, H. Ashihara, Phytochemistry 48, 777–779 (1998)
M. Kato, K. Mizuno, T. Fujimura, M. Iwama, M. Irie, A. Crozier, H. Ashihara, Plant Physiol. 120, 579–586 (1999)
U. Kela, R. Vijayvargiya, C.P. Trivedi, Life Sci. 27, 2109–2119 (1980)
B.A. Khilman, Mutat. Res. 26, 53–71 (1974)
C. Koshiishi, A. Kato, S. Yama, A. Crozier, H. Ashihara, FEBS Lett. 499, 50–54 (2001)
N. Kumar, S. Pandey, A. Bhattacharya, P.S. Ahuja, J. Biosci. 29, 309–317 (2004)
R.H. Kurtzman Jr., S. Schwimmer, Experientia 27, 481–482 (1971)
F. Leifa, A. Pandey, C.R. Soccol, J. Basic Microbiol. 40, 187–197 (2000)
M.M. Lorist, M. Tops, Brain Cogn. 53, 82–94 (2003)
K.M. Madyastha, G.R. Sridhar, B.B.Vadiraja, Y.S. Madhavi, Biochem. Biophys. Res. Commun. 263, 460–464 (1999)
M.J. Martin, F. Pablos, A.G. Gonzalez, Talanta 46, 1259–1264 (1998)
P. Mazzafera, Scientia Agricola 59, 815–821 (2002)
P. Mazzafera, A. Crozier, A.C. Magalhaes, Phytochemistry 30, 3913–3916 (1991)
P. Mazzafera, A. Crozier, G. Sandbergs, J. Agric. Food Chem. 42, 7423–7427 (1994)
W.J. Middelhoven, C.M. Bakker, Eur. J. Appl. Microbiol. Biotechnol. 15, 214–217 (1982)
K. Mizuno, M. Kato, F. Irino, N. Yoneyama, T. Fujimura, H. Ashihara, FEBS Lett. 547, 56–60 (2003)
B.R. Mohapatra, N. Harris, R. Nordin, A. Mazumdar, J. Biotechnol. 125, 319–327 (2006)
A. Nehlig, Neurosci. Biobehav. Rev. 23, 563–576 (1999)
A. Nehlig, J. Daval, G. Debry, Brain Res. Rev. 17, 139–170 (1992)
O.A. Ogunseitan, World J. Microbiol. Biotechnol. 12, 251–256 (1996)
X. Pan, G. Niu, H. Liu, Chem. Eng. Process 42, 129–133 (2003)
A. Pandey, C.R. Soccol, P. Nigam, D. Brand, R. Mohan, S. Roussos, Biochem. Eng. J. 6, 153–162 (2000)
A. Putrament, H. Baranowska, T. Bilinski, W. Prazmo, Mol. Gen. Genet. 118, 373–379 (1972)
S. Ramarethinam, N. Rajalakshmi, Indian J. Exp. Biol. 42, 575–580 (2004)
J.A. Ribeiro, A.M. Sebastião, A.D. Mendonça, Prog. Neurobiol. 68, 377–392 (2003)
J.B.U. Rojas, J.A.J. Verreth, S. Amato, E.S. Huisman, Bioresour. Technol. 89, 267–274 (2003)
S. Roussos, L. Hannibal, M.A. Aquiahuatl, M.R.T. Hernandes, S. Marakis, J. Food Sci. Technol. 31, 316–319 (1994)
S. Roussos, M.D.L. Angeles-Aquiahuatl, M.D.R. Trejo-Hernandez, I. Gaime-Perraud, E. Favela, M. Ramakrishna, M. Raimbault, V. Viniegra-Gonzalez, Appl. Microbiol. Biotechnol. 42, 756–762 (1995)
D. Salmones, G. Mata, K.N. Waliszewski, Bioresour. Technol. 93, 537–544 (2005)
V.R. Sarath Babu, S. Patra, M.S. Thakur, N.G. Karanth, M.C. Varadaraj, Enzyme Microb. Technol. 37, 617–624 (2005)
S. Schwimmer, R.H. Khurtzman Jr., E. Heftmann, Arch. Biochem. Biophys. 147, 109–113 (1971)
O.F.P. Sideso, A.C. Marvier, N.A. Katerelos, P.W. Goodenough, Int. J. Food Sci. Technol. 36, 693–698 (2001)
M.B. Silvarolla, P. Mazzafera, M.M.A. Lima, Genet. Mol. Biol. 23, 213–215 (2000)
I.L. Sin, Biochim. Biophys. Acta 410, 12–20 (1975)
A. Smith, Food Chem. Toxicol. 40, 1243–1255 (2002)
S.T. Smith, K.V. Rajagopalan, P. Handler, J. Biol. Chem. 242, 4108–4117 (1967)
C.V. Sundarraj, S. Dhala, Appl. Microbiol. 13, 432–436 (1965)
C.V. Tagliari, R.K. Sanson, A. Zanette, T.T. Franco, C.R. Soccol, Braz. J. Microbiol. 34, 102–104 (2003)
G. Theodoridis, P. Manesiotis, J. Chromatogr. A 948, 163–169 (2002)
G.D. Vogels, C.V.D. Drift, Bacteriol. Rev. 40, 403–468 (1976)
S.S.M. Waldhauser, J.A. Kretschmar, T.W. Baumann, Phytochemistry 44, 853–859 (1996)
B.A. Weinberg, B.K. Bealer, The World of Caffeine: The Science and Culture of the World’s Most Popular Drug (Routledge, New York, 2001)
P.A. White, J.B. Rasmussen, Mutat. Res. 410, 223–236 (1998)
C.A. Woolfolk, J. Bacteriol. 123, 1088–1106 (1975)
C.A. Woolfolk, B.S. Woolfolk, H.R. Whiteley, J. Biol. Chem. 245, 3167–3178 (1970)
D.M. Yamoka-Yano, P. Mazzafera, J. Allelopathy 5, 23–34 (1998)
D.M. Yamoka-Yano, P. Mazzafera, Rev. Microbiol. 30, 62–70 (1999)
Acknowledgements
Authors acknowledge Department of Science and Technology, Government of India and Indian Institute of Technology for financial support to carry out research work on microbial caffeine degradation.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media B.V.
About this chapter
Cite this chapter
Dash, S.S., Gummadi, S.N. (2012). Biotechnological Approach to Caffeine Degradation: Current Trends and Perspectives. In: Satyanarayana, T., Johri, B. (eds) Microorganisms in Sustainable Agriculture and Biotechnology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2214-9_20
Download citation
DOI: https://doi.org/10.1007/978-94-007-2214-9_20
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-2213-2
Online ISBN: 978-94-007-2214-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)