Abstract
The objective of this chapter is to systematically review the evidence for the effectiveness of qigong in supportive cancer care. Fifteen databases were searched from inception through May 2009. Controlled trials testing qigong in patients with cancer of any origin that assessed clinical outcome measures were considered. The selection of studies, data extraction, and validations were performed independently by two reviewers. Risk of bias was assessed using Cochrane criteria. Six randomized clinical trials (RCTs) and 5 non-randomized controlled clinical trials (CCTs) met our inclusion criteria. The six RCTs tested the effects of qigong as supportive cancer care compared with usual care or herbal medicine and showed no significant differences in most outcome measures. All of the 5 CCTs showed favourable effects of qigong. Two trials suggested effectiveness in prolonging life of cancer patients while one failed to do so. All of the CCTs had a high risk of bias. Collectively, the existing trial evidence does not show convincingly that qigong is effective for supportive cancer care. Future studies should be of high quality with a particular emphasis on designing an adequate control intervention.
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American Cancer Society. Cancer facts and figures 2008. http://www.cancer.org/downloads/STT/ 2008CAFFfinalsecured.pdf. Accessed 15 June 2009 2009:18.
Chen KW. An analytic review of studies on measuring effects of external qi in China. Altern Ther Health Med. 2004;10:38–50.
Chen K, Yeung R. Exploratory studies of qigong therapy for cancer in China. Integr Cancer Ther. 2002;1:345–70.
Courneya KS. Exercise in cancer survivors: an Overview of research. Med Sci Sports Exerc. 2003;35:1846–52.
Dy GK, Bekele L, Hanson LJ et al. Complementary and alternative medicine use by patients enrolled onto phase I clinical trials. J Clin Oncol. 2004;22:4810–5.
Egger M, Smith GD. Bias in location and selection of studies. BMJ. 1998;316:61–66.
Ernst E, Pittler MH. Alternative therapy bias. Nature. 1997;385:480.
Ernst E, Pittler M, Wider B et al. Oxford handbook of complementary medicine. Oxford, UK: Oxford University Press; 2008.
Frenkel M, Ben-Arye E, Baldwin CD et al. Approach to communicating with patients about the use of nutritional supplements in cancer care. South Med J. 2005;98:289–94.
Fu JZ, Fu SL, Qin JT. Effect of qigong and anticancer body-bulding herbs on the prognosis of postoperative patients with cardiac adenocarcinoma. Third World Conference on Medical Qigong 1996.
Fu JZ, Wang SM. Qigong plus herbal medicine in treating late-stage stomach cancer in the elderly. In: Lin ZP editors. Understanding of true qi cultivation and sublimation. Beijing, China: Chinese Publisher of Constructive Materials; 1995. 155–57.
Fu JZ, Zou ZK. Qigong combined with chemotherapy in the treatment of gastric cancer. In: Lin ZP editors. Understanding of true qi cultivation and sublimation. Beijing, China: Chinese Publisher of Constructive Materials; 1995. 157–8.
Hong EY. The effect of Yudongkong exercise in fatigue, difficulty of daily activities and symptoms of side effect in advanced gastric cancer patients receiving chemotherapy (Doctorial dissertation). Seoul, Korea: Yonsei University; 2003. 83.
Jones BM. Changes in cytokine production in healthy subjects practicing Guolin qigong: a pilot study. BMC Complement Altern Med. 2001;1:8.
Julian PTH, Douglas GA. Assessing risk of bias in included studies. In: Julian PT, Green S editors. Cochrane handbook for systematic reviews of interventions. West Sussex, England: Wiley-Blackwell; 2008. 187–241.
Kemp CA. Qigong as a therapeutic intervention with older adults. J Holist Nurs. 2004;22: 351–73.
Lam SWY. A randomized, controlled trial of Guolin qigong in patients receiving transcatheter arterial chemoembolisation for unresectable hepatocellular carcinoma (Master). Hong Kong: University of Hong Kong; 2004. 130.
Lee S. Chinese hypnosis can cause qigong induced mental disorders. BMJ. 2000;320:803.
Lee TI, Chen HH, Yeh ML. Effects of chan-chuang qigong on improving symptom and psychological distress in chemotherapy patients. Am J Chin Med. 2006;34:37–46.
Lee MS, Kim MK, Ryu H. Qi-training (qigong) enhanced immune functions: what is the underlying mechanism?. Int J Neurosci. 2005;115:1099–104.
Lee MS, Pittler MH, Ernst E. Is taichi an effective adjunct in cancer care? A systematic review of controlled clinical trials. Support Care Cancer. 2007;15:597–601.
Luo JF, He CW, Lu HH et al. Analysis of the impact of qigong for patients with nasopharyngeal carcinoma. Chin J Cancer. 1991;10:343–4.
Luo S, Tong T. Effects of vital gate qigong on malignant tumor. 1st World Conf Acad Exch Med Qigong, Beijing, China; 1988.
National Center for Complementary and Alternative Medicine. Cancer and complementary and alternative medicine. http://nccam.nih.gov/health/cancer/camcancer.htm. Accessed 15 June 2009.
Ng BY. Qigong-induced mental disorders: a review. Aust N Z J Psychiatry. 1999;33:197–206.
Oh B, Butow P, Mullan B et al. Medical qigong for cancer patients: pilot study of impact on quality of life, side effects of treatment and inflammation. Am J Chin Med. 2008;36:459–72.
Pittler MH, Abbot NC, Harkness EF et al. Location bias in controlled clinical trials of complementary/alternative therapies. J Clin Epidemiol. 2000;53:485–89.
Richardson MA, Sanders T, Palmer JL et al. Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology. J Clin Oncol. 2000;18:2505–14.
Sancier KM. Medical applications of qigong. Altern Ther Health Med. 1996;2:40–46.
Sancier KM. Therapeutic benefits of qigong exercises in combination with drugs. J Altern Complement Med. 1999;5:383–89.
Sun QZ, Zhao L. Clinical observation of qigong as a therapeutic aid for advanced cancer patients. First World Conference for Academic Exchange of Medical Qigong, Beijing, China; 1988.
Vickers A, Goyal N, Harland Rm et al. Do certain countries produce only positive results? A systematic review of controlled trials. Control Clin Trials. 1998;19:159–66.
Wang CH, Wang BR, Shao MY et al. Clinical study if the routine treatment if cancer coordinated by qigong. 2nd World Conference for Academic Exchange of Medical Qigong, 1993.
Wang Y, Ye M. Analysis of psychological err factors in assessment of therapeutic effect of qigong rehabilitation in cancer patients. Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai. 2002;16:20–22.
Wayne PM, Kaptchuk TJ. Challenges inherent to t’ai chi research: part II-defining the intervention and optimal study design. J Altern Complement Med. 2008;14:191–7.
World Health Organization. Cancer. http://www.who.int/cancer/en/Accessed 15 June 2009.
Yan X, Shen H, Jiang H et al. External qi of Yan Xin qigong differentially regulates the Akt and extracellular signal-regulated kinase pathways and is cytotoxic to cancer cells but not to normal cells. Int J Biochem Cell Biol. 2006;38:2102–13.
Yan X, Shen H, Jiang H et al. External qi of Yan Xin qigong induces G2/M arrest and apoptosis of androgen-independent prostate cancer cells by inhibiting Akt and NF-kappa B pathways. Mol Cell Biochem. 2008;310:227–34.
Zheng RR. Observation of 100 cases with comprehensive qigong therapy for treating later-stage cancer. World Qigong. 1990;3:19.
Acknowledgement
The authors specially thank Dr Tae-young Choi of the Korea Institute of Oriental Medicine (KIOM) for extensively searching the Chinese Databases. MS Lee was supported by KIOM (K09050).
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Lee, M.S., Chen, K.W., Ernst, E. (2010). Supportive Cancer Care with Qigong. In: Cho, W. (eds) Supportive Cancer Care with Chinese Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3555-4_4
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DOI: https://doi.org/10.1007/978-90-481-3555-4_4
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