Abstract
We have reported that sericin is useful for improving mammalian cell culture. However, the mechanism of how sericin induces cell proliferation and suppresses cell death has not been elucidated. In this study, we performed proteome analysis in order to identify up- or down-regulated proteins by sericin treatment. Proteome analysis using two-dimensional electrophoresis detected six proteins, suggesting some of them might be involved in the proliferative and anti-apoptotic effect of sericin.
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This work was partly supported by Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists.
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Yanagihara, K. et al. (2010). Involvement of SRC- and MAP Kinase-Signalings in the Effect of Sericin on Cellular Proliferation and Survival. In: Noll, T. (eds) Cells and Culture. ESACT Proceedings, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3419-9_75
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DOI: https://doi.org/10.1007/978-90-481-3419-9_75
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Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-3418-2
Online ISBN: 978-90-481-3419-9
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