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Frontotemporal Dementia

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Dementias

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Abstract

The principles for classification of organic dementia are based on our present knowledge of its etiology, clinical picture, and pathological characteristics such as the type and predominant location of the brain damage. This paper concerns the clinical and pathological findings in dementia cases with primary degenerative changes within the frontal and temporal lobes and the possibility to differentiate this frontotemporal dementia (FTD) from Alzheimer’s disease (AD) and other dementias. The importance of localized cortical atrophy within the frontal and temporal lobes in dementia was pointed out by Arnold Pick more than 100 years ago [1]. The neuropathological characteristics of this condition were given by Alzheimer [2], who described the ballooned cells and argentophilic inclusion bodies. The clinicopathological entity of this “Pick’s disease” or “lobar atrophy” was delineated by Onari and Spatz [3] and Schneider [4], and further elaborated in a series of important contributions [5–9].

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Authors
  1. L. Gustafson
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  2. A. Brun
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology, University of Pavia, Viale Taramelli 14, 27100, Pavia, Italy

    Stefano Govoni

  2. IRCCS “S. Giovanni di Dio”, “S. Cuore-Fatebenefratelli” Institute, Via Pilastroni 4, 25125, Brescia, Italy

    Stefano Govoni

  3. Consultant Office of Research Policy and Strategy Coordination of WHO, University of Milan, Italy

    Carla Liana Bolis

  4. Geriatric Research Group, Via Romanino 1, 25122, Brescia, Italy

    Marco Trabucchi

  5. Department of Neurosciences, University of Rome “Tor Vergata”, Rome, Italy

    Marco Trabucchi

  6. Alzheimer’s Unit, IRCCS “S. Giovanni di Dio”, “S. Cuore-Fatebenefratelli” Institute, Via Pilastroni 4, 25125, Brescia, Italy

    Marco Trabucchi

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© 1999 Springer-Verlag Italia

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Gustafson, L., Brun, A. (1999). Frontotemporal Dementia. In: Govoni, S., Bolis, C.L., Trabucchi, M. (eds) Dementias. Springer, Milano. https://doi.org/10.1007/978-88-470-2149-5_7

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  • DOI: https://doi.org/10.1007/978-88-470-2149-5_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0048-3

  • Online ISBN: 978-88-470-2149-5

  • eBook Packages: Springer Book Archive

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