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Cultured Skin Fibroblasts from Hereditary Colorectal Cancer Patients: Susceptibility Mechanisms, Genetics, and Biomarkers

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Hereditary Colorectal Cancer

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Abstract

The present studies illustrate the utility of biomarkers that occur systemically in skin fibroblasts of patients with hereditary adenomatosis of the colon and rectum, an autosomal dominant trait. These biomarkers provide insight into the initiated cell phenotype, susceptibility mechanisms, genetic alterations during colorectal cancer, and potential therapeutic approaches.

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Authors
  1. Levy Kopelovich
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Editors and Affiliations

  1. Second Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663, Japan

    Joji Utsunomiya M. D. (Professor and Chairman) (Professor and Chairman)

  2. Department of Preventive Medicine, Creighton University School of Medicine, Hereditary Cancer Center, California at 24th Street, Omaha, NE, 68178, USA

    Henry T. Lynch M. D. (Professor and Chairman) (Professor and Chairman)

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© 1990 Springer Japan

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Kopelovich, L. (1990). Cultured Skin Fibroblasts from Hereditary Colorectal Cancer Patients: Susceptibility Mechanisms, Genetics, and Biomarkers. In: Utsunomiya, J., Lynch, H.T. (eds) Hereditary Colorectal Cancer. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68337-7_58

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  • DOI: https://doi.org/10.1007/978-4-431-68337-7_58

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68339-1

  • Online ISBN: 978-4-431-68337-7

  • eBook Packages: Springer Book Archive

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