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Helicobacter pylori Research pp 543–574Cite as

Probiotics as an Alternative Therapy for Helicobacter pylori-Associated Diseases

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Abstract

Probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit to the host. Probiotics are not part of the current treatment therapies prescribed for Helicobacter pylori eradication, but there are numerous studies, most of them using probiotics as adjuvants to therapy, showing a reduction of side effects in the greater majority of cases. The probiotics administered vary hugely in the composition of microorganisms used, as well as the duration and mode of administration, which renders the comparison difficult. However, the most used probiotics for H. pylori infection are composed of Lactobacillus, Bifidobacterium, Saccharomyces, and Streptococcus. The mode of action of these probiotics relies on competition for nutrients and for adhesion to cell receptors, antimicrobial activity, and modulation of the immune system and microbiota.

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Authors and Affiliations

  1. Laboratoire de Bactériologie, Université de Bordeaux, Bordeaux, France

    Filipa F. Vale

  2. INSERM U853, Bordeaux, France

    Filipa F. Vale

  3. Host-Pathogen Interaction Unit, Research Institute for Medicines (iMed-ULIsboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal

    Filipa F. Vale

  4. Biochemistry and Human Biology Department, Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal

    Jorge M. B. Vítor

  5. Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, Av. Padre Cruz, 1649-016, Lisboa, Portugal

    Mónica Oleastro

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  1. Filipa F. Vale
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  2. Jorge M. B. Vítor
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  3. Mónica Oleastro
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Correspondence to Filipa F. Vale .

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  1. Division of Microbiology;Dept of Biology, Friedrich Alexander Univ;Erlangen-Nuremb, Erlangen, Bayern, Germany

    Steffen Backert

  2. Dept of Medicine-Gastroenteology, Baylor College of Medicine, Houston, USA

    Yoshio Yamaoka

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Vale, F.F., Vítor, J.M.B., Oleastro, M. (2016). Probiotics as an Alternative Therapy for Helicobacter pylori-Associated Diseases. In: Backert, S., Yamaoka, Y. (eds) Helicobacter pylori Research. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55936-8_24

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