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Components and Mechanisms in Mitochondrial Protein Import

  • Chapter
Cell Organelles

Part of the book series: Plant Gene Research ((GENE))

Abstract

The biogenesis of mitochondrial proteins requires two genetic systems. Less than 5% of mitochondrial proteins are encoded by mitochondrial genes and are synthesized within the organelle. The vast majority of mitochondrial proteins are encoded by nuclear genes and are synthesized as precursor proteins on cytosolic polysomes (Douglas et al., 1986; Rosenberg et al, 1987; Attardi and Schatz, 1988; Pfanner et al., 1988a; Hartl et al., 1989; Pfanner and Neupert, 1989; Lonsdale and Grienenberger, 1992) (Fig. 1). Therefore, several hundred different proteins have to be imported into mitochondria. The transport of precursor proteins into mitochondria comprises a complex series of steps, including targeting, membrane translocation, and assembly of the proteins.

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  1. Institut für Physiologische Chemie, Universität München, D-W-8000, München 2, Federal Republic of Germany

    Nikolaus Pfanner

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  1. Nikolaus Pfanner
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  1. Botanisches Institut, Ludwig-Maximilians-Universität, Munich, Germany

    Reinhold G. Herrmann

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© 1992 Springer-Verlag/Wien

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Pfanner, N. (1992). Components and Mechanisms in Mitochondrial Protein Import. In: Herrmann, R.G. (eds) Cell Organelles. Plant Gene Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9138-5_11

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  • DOI: https://doi.org/10.1007/978-3-7091-9138-5_11

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9140-8

  • Online ISBN: 978-3-7091-9138-5

  • eBook Packages: Springer Book Archive

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