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Nerve-Driven Immunity pp 47–96Cite as

Nerve Driven Immunity: Noradrenaline and Adrenaline

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Abstract

Noradrenaline and adrenaline belong to catecholamines, a family of chemical compounds containing a catechol or 3,4-dihydroxyphenyl group and an amine function. Together with dopamine, they are the most abundant and important catecholamines in the human body and are all produced from tyrosine, a non-essential amino acid which is both obtained from dietary proteins or in turn synthesized from the essential amino acid phenylalanine by the enzyme phenylalanine hydroxylase. Noradrenaline is synthesized from dopamine by dopamine β-hydroxylase and is converted to adrenaline by phenylethanolamine N-methyltransferase (Fig. 2.1). The natural stereoisomers are l-(-)-(R)-noradrenaline and adrenaline.

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  1. Center for Research in Medical Pharmacology, University of Insubria, Via Ottorino Rossi n. 9, 21100, Varese, VA, Italy

    Marco Cosentino MD PhD & Franca Marino

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  1. Marco Cosentino MD PhD
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  2. Franca Marino
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  1. School of Behavioral Sciences, The Academic College of TLV Yaffo, Rabenu Yeruham Street 29, Yaffo, 61083, Israel

    Mia Levite

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Cosentino, M., Marino, F. (2012). Nerve Driven Immunity: Noradrenaline and Adrenaline. In: Levite, M. (eds) Nerve-Driven Immunity. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0888-8_2

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