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Skin Reactivity of the Human Face: Functional Map and Age Related Differences

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Textbook of Aging Skin

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Abstract

The skin of the human face is much more complex and diverse, physiologically, than to be expected. It is imperative to observe and understand the variation that exists among the various regions of face skin. The aim of this chapter was to discuss the findings of studies that assess these regions in terms of biophysical parameters: upper dermis vascularization, stratum corneum turnover, transepidermal water loss, stratum corneum hydration, skin temperature, skin sebum content, and pH. The nasolabial region showed highest values for stratum corneum turnover (in the younger group), transepidermal water loss, skin temperature, and sebum content. Laser Doppler flowmeter (LDF) revealed that upper dermis vascularization was highest in the nasal region. Hydration was highest in the neck, and pH was highest (most alkaline) in the chin. Additionally, this chapter examines studies that evaluated reactivity of the skin of various facial regions in response to hexyl nicotinate and sodium lauryl sulfate. In terms of skin reactivity, induction of nonimmunologic contact urticaria by hexyl nicotinate showed highest values in the chin (of aged group), while sodium lauryl sulfate was nonreactive in the forearm.

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Author information

Authors and Affiliations

  1. Department of Dermatology, University of California, 90 Medical Center Way, Surge 110, San Francisco, CA, 94143-0989, USA

    John Jay P. Cadavona & Howard I. Maibach

  2. Department of Dermatology, Hedi Chaker Hospital, Sfax, Tunisia

    Slaheddine Marrakchi

Authors
  1. John Jay P. Cadavona
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  2. Slaheddine Marrakchi
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  3. Howard I. Maibach
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Corresponding author

Correspondence to John Jay P. Cadavona .

Editor information

Editors and Affiliations

  1. Winton Hill Business Center, The Procter & Gamble Company , Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Margoshes-Miller Consulting, LLC, Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. Department of Dermatology, University of California, San Francisco, California, USA

    Howard I. Maibach

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Cadavona, J.P., Marrakchi, S., Maibach, H.I. (2017). Skin Reactivity of the Human Face: Functional Map and Age Related Differences. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47398-6_17

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  • DOI: https://doi.org/10.1007/978-3-662-47398-6_17

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-47397-9

  • Online ISBN: 978-3-662-47398-6

  • eBook Packages: MedicineReference Module Medicine

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