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Operative und interventionelle Gefäßmedizin pp 1–14Cite as

Aneurysmatische Gefäßerkrankungen: Terminologie, Ätiologie und Lokalisation

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Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Bei einem Aneurysma handelt es sich um eine umschriebene Erweiterung eines Gefäßes. In diesem Kapitel werden die Ursachen der verschieden Formen und Lokalisationen von Aneurysmen dargestellt. Da die genetischen und molekularen Grundlagen vor allem am abdominellen Aortenaneurysma (AAA) untersucht worden sind, diesen diese Aneurysmen hier im Fokus. Drei Prozesse stehen hierbei im Vordergrund bei der Ausbildung solcher Aneurysmen: Die Degradation der extrazellulären Matrix, ein chronischer Entzündungsprozess sowie eine Reduktion der mesenchymalen Muskelzellen.

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Literatur

  • Agarwal S (2009) The association of active and passive smoking with peripheral arterial disease: results from NHANES 1999–2004. Angiology 60:335–345 [Im Druck]

    Article  PubMed  Google Scholar 

  • Allen EV, Brown GE (1932) Raynaud’s disease: a critical review of minimal requisites for diagnosis. Am J Med Sci 183(2):187–200

    Article  Google Scholar 

  • Aly S, Jenkins MP, Zaidi FH et al (1998) Duplex scanning and effect of multisegmental arterial disease on its accuracy in lower limb arteries. Eur J Vasc Endovasc Surg 16:345–349

    Article  CAS  PubMed  Google Scholar 

  • Archer SL, Huang JM, Hampl V et al (1994) Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A 91:7583–7587

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Avierinos JF, Gersh BJ, Melton LJ 3rd, Bailey KR, Shub C, Nishimura RA, Tajik AJ, Enriquez-Sarano M (2002) Natural history of asymptomatic mitral valve prolapse in the community. Circulation 106(11):1355–1361

    Article  PubMed  Google Scholar 

  • Aydin MA, Koschyk DH, Karck M, Cremer J, Haverich A, Berger J, Nienaber CA, Meinertz T, von Kodolitsch Y (2002) Prädiktoren der Aneurysmaentwicklung nach chirurgischer Korrektur einer Aortenisthmusstenose. Z Kardiol 91(suppl1):I/338 (A)

    Google Scholar 

  • Aydin A, Mortensen K, Rybczynski M, Sheikhzadeh S, Willmann S, Bernhardt AM, Hillebrand M, Stritzke J, Baulmann J, Schunkert H, Keil U, Hense HW, Meisinger C, Robinson PN, Berger J, Willems S, Meinertz T, von Kodolitsch Y (2011) Central pulse pressure and augmentation index in asymptomatic bicuspid aortic valve disease. Int J Cardiol 147(3):466–468

    Article  PubMed  Google Scholar 

  • Baldwin ZK, Ceraldi CC (2003) Ergotism associated with HIV antiviral protease inhibitor therapy. J Vasc Surg 37(3):676–678

    Article  PubMed  Google Scholar 

  • Baril DT, Carroccio A, Palchik E, Ellozy SH, Jacobs TS, Teodorescu V, Marin ML (2006) Endovascular treatment of complicated aortic aneurysms in patients with underlying arteriopathies. Ann Vasc Surg 20(4):464–471

    Article  PubMed  Google Scholar 

  • Beasley JM, Ange BA, Anderson CA, Miller ER 3rd, Erlinger TP, Holbrook JT, Sacks FM, Appel LJ (2009) Associations between macronutrient intake and self-reported appetite and fasting levels of appetite hormones: results from the optimal macronutrient intake trial to prevent heart disease. Am J Epidemiol 169:893–900

    Article  PubMed  PubMed Central  Google Scholar 

  • Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ (1998) Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK). Am J Med Genet 77(1):31–37

    Article  CAS  PubMed  Google Scholar 

  • Bekanntmachungen (2007) Beschluss des Gemeinsamen Bundesausschusses gem. § 91 Abs. 4 SGB V vom 15. August 2006. Deutsches Ärzteblatt

    Google Scholar 

  • Belch JJ, Newman P, Drury JK, McKenzie F, Capell H, Leiberman P, Forbes CD, Prentice CR (1983) Intermittent epoprostenol (prostacyclin) infusion in patients with Raynaud’s syndrome: a double-blind controlled trial. Lancet 1:313–315

    Article  CAS  PubMed  Google Scholar 

  • Bergqvist D, Jivegard L, Holm J (1995) When is urgent revascularisation necessary for the lower limb ischemia? Eur J Vasc Endovasc Surg 9:448–453

    Article  PubMed  Google Scholar 

  • Bernhagen J, Krohn R, Lue H, Gregory JL, Zernecke A, Koenen RR, Dewor M, Georgiev I, Schober A, Leng L, Kooistra T, Fingerle-Rowson G, Ghezzi P, Kleemann R, McColl SR, Bucala R, Hickey MJ, Weber C (2007) MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med 13:587–596

    Article  CAS  PubMed  Google Scholar 

  • Bernhardt A, Treede H, Rybczynski M, Sheikzadeh S, Detter C, von Kodolitsch Y, Reichenspurner H (2011) Mitral valve surgery in patients with Marfan syndrome. J Thorac Cardiovasc Surg (under review)

    Google Scholar 

  • Bernhardt AM, Treede H, Rybczynski M, Sheikzadeh S, Kersten JF, Meinertz T, von Kodolitsch Y, Reichenspurner H (2011b) Comparison of aortic root replacement in patients with Marfan syndrome. Eur J Cardiothorac Surg 40:1052–1057

    PubMed  Google Scholar 

  • Bettoni L, Geri A, Airo P, Danieli E, Cavazzana I, Antonioli C, Chiesa L, Franceschini F, Grottolo A, Zambruni A, Radaeli E, Cattaneo R (2002) Systemic sclerosis therapy with iloprost: a prospective observational study of 30 patients treated for a median of 3 years. Clin Rheumatol 21(3):244–250

    Article  CAS  PubMed  Google Scholar 

  • Bock I (2003) Die Behandlung der arteriellen Verschlusserkrankung durch femorodistale Bypassimplantation – ein follow up nach 270 Bypassimplantationen. Inauguraldissertation, Lübeck

    Google Scholar 

  • Böckler D, Lang W, Debus ES, Flessenkämper I, Florek HJ, Noppeney T, Schmitz-Rixen T, Nöldecke S, Hupp T, Eckstein H (2009) Randomisierte Studien mit EBM-Level 1 beweisen es. Gefässchirurgie 14:350–361

    Article  Google Scholar 

  • Bole PV, Munda R, Purdy RT, Lande A, Gomez R, Clauss RH, Kazarian KK, Mersheimer WL (1976) Traumatic pseudoaneurysms: a review of 32 cases. J Trauma 16:63–70

    Article  CAS  PubMed  Google Scholar 

  • Bollinger A, Schlumpf M (1976) Finger blood flow in healthy subjects of different age and sex and in patients with primary Raynaud’s disease. Acta Chir Scand Suppl 465:42–47

    CAS  PubMed  Google Scholar 

  • Bollinger A, Mahler F, Meier B (1977) Velocity patterns in nailfold capillaries of normal subjects and patients with Raynaud’s disease and acrocyanosis. Bibl Anat 16:142–145

    PubMed  Google Scholar 

  • Boon RA, Horrevoets AJ (2009) Key transcriptional regulators of the vasoprotective effects of shear stress. Hamostaseologie 29:39–40

    CAS  PubMed  Google Scholar 

  • Botta L, Russo V, La Palombara C, Rosati M, Di Bartolomeo R, Fattori R (2009) Stent graft repair of descending aortic dissection in patients with Marfan syndrome: an effective alternative to open reoperation? J Thorac Cardiovasc Surg 138(5):1108–1114

    Article  PubMed  Google Scholar 

  • Brossmann J, Müller-Hülsbeck S, Heller M et al (1998) Perkutane Thrombektomie und mechanische Thrombolyse. Fortschr Röntgenstr 169:344–354

    Article  CAS  Google Scholar 

  • Caglayan E, Huntgeburth M, Karasch T, Weihrauch J, Hunzelmann N, Krieg T, Erdmann E, Rosenkranz S (2006) Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud’s disease. Arch Intern Med 166(2):231–233

    Article  CAS  PubMed  Google Scholar 

  • Calligaro KD, Dougherty MJ (2005) Renal Artery Aneurysms and arteriovenous Fistulae. In: Rutherford RB (Hrsg) Vascular surgery, Bd 6. Elsevier Saunders, Philadelphia, S 1861–1870

    Google Scholar 

  • Cerwinka WH, Cooper D, Krieglstein CF et al (2002) Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol 282:1111–1117

    Article  Google Scholar 

  • Chelland Campbell S, Moffatt RJ, Stamford BA (2008) Smoking and smoking cessation – the relationship between cardiovascular disease and lipoprotein metabolism: a review. Atherosclerosis 201:225–235

    Article  PubMed  CAS  Google Scholar 

  • Chen HW, Lii CK, Ku HJ, Wang TS (2009) Cigarette smoke extract induces expression of cell adhesion molecules in HUVEC via actin filament reorganization. Environ Mol Mutagen 50:96–104

    Article  CAS  PubMed  Google Scholar 

  • Choudhary AS, Evans RJ, Naik DK, Tripathi RK, Wickremesekera JK (2009) Surgical management of extracranial carotid artery aneurysms. ANZ J Surg 79:281–287

    Article  PubMed  Google Scholar 

  • Cistulli PA, Gotsopoulos H, Sullivan CE (2001) Relationship between craniofacial abnormalities and sleep-disordered breathing in Marfan’s syndrome. Chest 120:1455–1460

    Article  CAS  PubMed  Google Scholar 

  • Coffman JD, Cohen RA (1988) Role of alpha-adrenoceptor subtypes mediating sympathetic vasoconstriction in human digits. Eur J Clin Invest 18(3):309–313

    Article  CAS  PubMed  Google Scholar 

  • Collod G, Babron MC, Jondeau G, Coulon M, Weissenbach J, Dubourg O, Bourdarias JP, Bonaiti-Pellie C, Junien C, Boileau C (1994) A second locus for Marfan syndrome maps to chromosome 3p24.2–p25. Nat Genet 198:264–268

    Google Scholar 

  • Costantini V, Lend M (2002) Treatment of acute occlusion of peripheral arteries. Thromb Res 106:285–294

    Article  Google Scholar 

  • Cotrufo M, Della Corte A (2009) The association of bicuspid aortic valve disease with asymmetric dilatation of the tubular ascending aorta: identification of a definite syndrome. J Cardiovasc Med (Hagerstown) 10(4):291–297

    Article  Google Scholar 

  • Curci JA, Baxter BT, Thompson RW (2005) Arterial aneurysms: etiologic considerations. In: Rutherford RB (Hrsg) Vascular surgery, Bd 6. Elsevier Saunders, Philadelphia, S 475–492

    Google Scholar 

  • Cyron CJ, Wilson JS, Humphrey JD (2014) Mechanobiological stability: a new paradigm to understand the enlargement of aneurysms? J R Soc Interface 11:20140680

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, García-Cardeña G, Gimbrone MA Jr (2004) Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. PNAS 101:14871–14876

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA Jr (2007) Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2. Circ Res 101:723–733

    Article  CAS  PubMed  Google Scholar 

  • Davis FM, Rateri DL, Daugherty A (2014) Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies. Heart 100:1498–1505

    Article  CAS  PubMed  Google Scholar 

  • Davis FM, Rateri DL, Daugherty A (2015) Abdominal aortic aneurysm: novel mechanisms and therapies. Curr Opin Cardiol 30:566–573

    Article  PubMed  Google Scholar 

  • De Paepe A, Devereux RB, Dietz HC, Hennekam RC, Pyeritz RE (1996) Revised diagnostic criteria for the Marfan syndrome. Am J Med Genet 62(4):417–426

    Article  PubMed  Google Scholar 

  • Debus ES, Kölbel T, Böckler D, Eckstein H (2010) Abdominelle Aortenaneurysmen. Gefässchirurgie 15:154–168

    Article  Google Scholar 

  • Dedow E, Bangemann U, Koenig H (2002) Die Ergebnisse der intraartieriellen rTPA Lyse verschlossener femoro-distaler Bypasse. In: Hepp W (Hrsg) Akuter Extremitäten-Arterienverschluß. Steinkopff, Darmstadt

    Google Scholar 

  • Deguchi J et al (2009) Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II. Lab Invest 89:315–326

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Der akute Gefäßverschluß – was ist zu tun? www.gefaesschirurgie.de

  • Dimmeler S, Zeiher AM (1999) Nitric oxide-an endothelial cell survival factor. Cell Death Differ 6:964–968

    Article  CAS  PubMed  Google Scholar 

  • Dobrin PB, Baker WH, Gley WC (1984) Elastolytic and collagenolytic studies of arteries. Implications for the mechanical properties of aneurysms. Arch Surg 119:405–409

    Article  CAS  PubMed  Google Scholar 

  • Dormandy J, Heeck L, Vig S (1999) Acute limb ischemia. Semin Vasc Surg 12:148–153

    CAS  PubMed  Google Scholar 

  • Dotter CT, Roesch J, Seaman A (1974) Selective clot lysis with low-dose streptokinase. Radiology 111:31–37

    Article  CAS  PubMed  Google Scholar 

  • Dowd PM, Martin MF, Cooke ED, Bowcock SA, Jones R, Dieppe PA, Kirby JD (1982) Treatment of Raynaud’s phenomenon by intravenous infusion of prostacyclin (PGI2). Br J Dermatol 106(1):81–89

    Article  CAS  PubMed  Google Scholar 

  • Duda SH, Tepe G, Luz O, Ouriel K, Dietz K, Hahn U, Pereira P, Marsalek P, Ziemer G, Erley CM, Claussen CD (2001) Peripheral artery occlusion: treatment with abciximab plus urokinase versus with urokinase alone – a randomized pilot trial (the PROMPT study). Platelet receptor antibodies in order to manage peripheral artery thrombosis. Radiology 221(3):689–96

    Article  CAS  PubMed  Google Scholar 

  • Dziadzio M, Denton CP, Smith R, Howell K, Blann A, Bowers E, Black CM (1999) Losartan therapy for Raynaud’s phenomenon and scleroderma: clinical and biochemical findings in a fifteen-week, randomized, parallel-group, controlled trial. Arthritis Rheum 42(12):2646–2655

    Article  CAS  PubMed  Google Scholar 

  • Eadie MJ (2001) Clinically significant drug interactions with agents specific for migraine attacks. CNS Drugs 15(2):105–118

    Article  CAS  PubMed  Google Scholar 

  • Eckstein HH (1998) Akute Extremitätenischämie. Chirurg 69:786–800

    Article  CAS  PubMed  Google Scholar 

  • El Menyar AA (2006) Drug-induced myocardial infarction secondary to coronary artery spasm in teenagers and young adults. J Postgrad Med 52(1):51–56

    PubMed  Google Scholar 

  • Elkind MS (2009) Inflammatory markers and stroke. Curr Cardiol Rep 11:12–20

    Article  PubMed  Google Scholar 

  • Elmore JR, Keister BF, Franklin DP, Youkey JR, Carey DJ (1998) Expression of matrix metalloproteinases and TIMPs in human abdominal aortic aneurysms. Ann Vasc Surg 12:221–228

    Article  CAS  PubMed  Google Scholar 

  • El-Sabrout R, Cooley DA (2000) Extracranial carotid artery aneurysms: Texas Heart Institute experience. J Vasc Surg 31:702–712

    Article  CAS  PubMed  Google Scholar 

  • Evans JM, O’Fallon WM, Hunder GG (1995) Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis. A population-based study. Ann Intern Med 122:502–507

    Article  CAS  PubMed  Google Scholar 

  • Faggioli G, Ferri M, Rapezzi C, Tonon C, Manzoli L, Stella A (2009) Atherosclerotic aortic lesions increase the risk of cerebral embolism during carotid stenting in patients with complex aortic arch anatomy. J Vasc Surg 49:80–85

    Article  PubMed  Google Scholar 

  • Faivre L, Collod-Beroud G, Loeys BL, Child A, Binquet C, Gautier E, Callewaert B, Arbustini E, Mayer K, Arslan-Kirchner M, Kiotsekoglou A, Comeglio P, Marziliano N, Dietz HC, Halliday D, Beroud C, Bonithon-Kopp C, Claustres M, Muti C, Plauchu H, Robinson PN, Ades LC, Biggin A, Benetts B, Brett M, Holman KJ, De Backer J, Coucke P, Francke U, De Paepe A, Jondeau G, Boileau C (2007) Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study. Am J Hum Genet 281(3):454–466

    Article  CAS  Google Scholar 

  • Fillinger MF, Raghavan ML, Marra SP, Cronenwett JL, Kennedy FE (2002) In vivo analysis of mechanical wall stress and abdominal aortic aneurysm rupture risk. J Vasc Surg 36:589–597

    Article  PubMed  Google Scholar 

  • Foresta C, Caretta N, Corona G, Fabbri A, Francavilla S, Jannini E, Maggi M, Bettocchi C, Lenzi A (2009) Clinical and metabolic evaluation of subjects with erectile dysfunction: a review with a proposal flowchart. Int J Androl 32(3):198–211

    Article  CAS  PubMed  Google Scholar 

  • Friedman EA, Harris PA, Wood AJ, Stein CM, Kurnik D (2007) The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud’s phenomenon. Clin Pharmacol Ther 81(4):503–509

    Article  CAS  PubMed  Google Scholar 

  • Fries R, Shariat K, von Wilmowsky H, Bohm M (2005) Sildenafil in the treatment of Raynaud’s phenomenon resistant to vasodilatory therapy. Circulation 112:2980–2985

    CAS  PubMed  Google Scholar 

  • Fusco MR, Harrigan MR (2010) Cerebrovascular dissections: a review part II. Blunt cerebrovascular injury. Neurosurgery 68(2):517–553

    Article  Google Scholar 

  • Gambaryan S, Kobsar A, Hartmann S et al (2008) NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity. J Thromb Haemost 6:1376–1384

    Article  CAS  PubMed  Google Scholar 

  • Gardinali M, Pozzi MR, Bernareggi M, Montani N, Allevi E, Catena L, Cugno M, Bottasso B, Stabilini R (2001) Treatment of Raynaud’s phenomenon with intravenous prostaglandin E1 alpha-cyclodextrin improves endothelial cell injury in systemic sclerosis. J Rheumatol 28(4):786–794

    CAS  PubMed  Google Scholar 

  • Geerts CC, Bots ML, Grobbee DE, Uiterwaal CS (2008) Parental smoking and vascular damage in young adult offspring: is early life exposure critical? The atherosclerosis risk in young adults study. Arterioscler Thromb Vasc Biol 28:2296–2302

    Article  CAS  PubMed  Google Scholar 

  • Geisbusch P, Kotelis D, von Tengg-Kobligk H, Hyhlik-Durr A, Allenberg JR, Bockler D (2008) Thoracic aortic endografting in patients with connective tissue diseases. J Endovasc Ther 15(2):144–149

    Article  PubMed  Google Scholar 

  • Giannoglou G, Giannakoulas G, Hatzitolios AI, Rudolf J (2008) Rupture risk of abdominal aortic aneurysms. The role of computational mechanics. Herz 33:354–361

    Article  PubMed  Google Scholar 

  • Gott VL, Greene PS, Alejo DE, Cameron DE, Naftel DC, Miller DC et al (1999) Replacement of the aortic root in patients with Marfan’s syndrome. N Engl J Med 340(17):1307–13

    Article  CAS  PubMed  Google Scholar 

  • Gray JR, Davies SJ (1996) A clinical severity grading scale for Marfan syndrome. J Med Genet 33(9):758–759

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gross J, Lapiere CM (1962) Collagenolytic activity in amphibian tissues: a tissue culture assay. Proc Natl Acad Sci U S A 48:1014–1022

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Habashi JP, Judge DP, Holm TM, Cohn RD, Loeys BL, Cooper TK, Myers L, Klein EC, Liu G, Calvi C, Podowski M, Neptune ER, Halushka MK, Bedja D, Gabrielson K, Rifkin DB, Carta L, Ramirez F, Huso DL, Dietz HC (2006) Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science 312:117–121

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Halter G, Orend KH, Sunder-Plassmann L (2003) Die akute Extremitätenischämie. Chirurg 74:1118–1127

    Article  CAS  PubMed  Google Scholar 

  • Hellenthal FA, Geenen IL, Teijink JA, Heeneman S, Schurink GW (2008) Histological features of human abdominal aortic aneurysm are not related to clinical characteristics. Cardiovasc Pathol 18(5):286–293

    Article  PubMed  Google Scholar 

  • Henke PK (2009) Contemporary management of acute limb ischemia: factors associated with amputation and in-hospital mortality. Semin Vasc Surg 22:34–40

    Article  PubMed  Google Scholar 

  • Hepp W (2002) Akuter Extremitäten-Arterienverschluß. Steinkopff, Darmstadt

    Book  Google Scholar 

  • Herskowitz MM, Gillego V, Ward M, Wright G (2002) Cocaine-induced mesenteric ischemia: treatment with intra-arterial papaverine. Emerg Radiol 9(3):172–174

    Article  PubMed  Google Scholar 

  • Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, Eagle KA, Hermann LK, Isselbacher EM, Kazerooni EA, Kouchoukos NT, Lytle BW, Milewicz DM, Reich DL, Sen S, Shinn JA, Svensson LG, Williams DM (2010) 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: a report of the American college of cardiology foundation/American heart association task force on practice guidelines, American association for thoracic surgery, American college of radiology, American stroke association, society of cardiovascular anesthesiologists, society for cardiovascular angiography and interventions, society of interventional radiology, society of thoracic surgeons, and society for vascular medicine. Circulation 121(13):e266–e369

    Article  PubMed  Google Scholar 

  • Hirsch AT, Haskal ZJ, Hertzer NR (2006) ACC/AHA guidelines for the management of patients with peripheral arterial disease. J Vasc Interv Radiol 17:1383–1387

    Article  PubMed  Google Scholar 

  • Hirschl M, Katzenschlager R, Francesconi C, Kundi M (2004) Low level laser therapy in primary Raynaud’s phenomenon – results of a placebo controlled, double blind intervention study. J Rheumatol 31(12):2408–2412

    PubMed  Google Scholar 

  • Homme JL, Aubry MC, Edwards WD, Bagniewski SM, Shane Pankratz V, Kral CA, Tazelaar HD (2006) Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases. Am J Surg Pathol 30(9):1159–1168

    Article  PubMed  Google Scholar 

  • Homme JL, Aubry MC, Edwards WD, Bagniewski SM, Shane Pankratz V, Kral CA, Tazelaar HD (2008) Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases. Am J Surg Pathol 30(9):1159–1168

    Google Scholar 

  • Husmann MJ, Barton M, Jacomella V, Silvestro V, Amann-Vesti B (2006) Long-term effects of endovascular angioplasty on orthostatic vasocutaneous autoregulation in patients with peripheral atherosclerosis. J Vasc Surg 44(5):993–997

    Article  PubMed  Google Scholar 

  • Jahnke TH (2010) Management akuter Extremitätenischämien. In: Lindhoff-Last E, Debus ES, Kellersmann R, Tepe G (Hrsg) Handbuch Interdisziplinäre Angiologie, Kap. 12. Springer, Berlin/Heidelberg/New York

    Google Scholar 

  • Jamieson GG, Ludbrook J, Wilson A (1971) Cold hypersensitivity in Raynaud’s phenomenon. Circulation 44:254–264

    Article  CAS  PubMed  Google Scholar 

  • Jivegard L, Holm J, Schersten T (1998) Acute limb ischemia due to arterial embolism or thrombosis: influence of limb ischemia versus pre-existing cardiac disease on postoperative mortality rate. J Cardiovasc Surg 29:32–36

    Google Scholar 

  • Jülke M, Leu HJ (1985) Extraaortale arterielle Aneurysmen. Analyse von 163 Aneurysmen bei 142 Patienten. Schweiz Med Wochenschr 115:10–13

    PubMed  Google Scholar 

  • Juvonen J, Juvonen T, Laurila A, Alakarppa H, Lounatmaa K, Surcel HM, Leinonen M, Kairaluoma MI, Saikku P (1996) Immunohistochemical detection of Chlamydia pneumoniae in abdominal aortic aneurysms. Ann N Y Acad Sci 800:236–238

    Article  CAS  PubMed  Google Scholar 

  • Kalinowski M, Wagner H-J (2003) Adjunctive techniques in percutaneous mechanical thrombectomy. Tech Vasc Interv Radio 6:6–13

    Article  Google Scholar 

  • Kallio K et al (2009) Decreased aortic elasticity in healthy 11-year-old children exposed to tobacco smoke. Pediatrics 123(2):e267–e273

    Article  PubMed  Google Scholar 

  • Kasashima S, Zen Y, Kawashima A, Konishi K, Sasaki H, Endo M, Matsumoto Y, Kawakami K, Kasashima F, Moriya M, Kimura K, Ohtake H, Nakanuma Y (2008) Inflammatory abdominal aortic aneurysm: close relationship to IgG4-related periaortitis. Am J Surg Pathol 32:197–204

    Article  PubMed  Google Scholar 

  • Kasashima S, Zen Y, Kawashima A, Endo M, Matsumoto Y, Kasashima F (2009) A new clinicopathological entity of IgG4-related inflammatory abdominal aortic aneurysm. J Vasc Surg 49:1264–1271 [im Druck]

    Article  PubMed  Google Scholar 

  • Keller G, Zimmer G, Mall G, Ritz E, Amann K (2003) Nephron number in patients with primary hypertension. N Engl J Med 348:101–108

    Article  PubMed  Google Scholar 

  • Khanafer KM, Bull JL, Upchurch GR Jr, Berguer R (2007) Turbulence significantly increases pressure and fluid shear stress in an aortic aneurysm model under resting and exercise flow conditions. Ann Vasc Surg 21:67–74

    Article  PubMed  Google Scholar 

  • Kimmelstiel P, Wilson C (1936) Benign and malignant hypertension and nephrosclerosis. A clinical and pathological study. Am J Pathol 12:45–48

    CAS  PubMed  PubMed Central  Google Scholar 

  • Knoflach M et al (2009) Cardiovascular risk factors and atherosclerosis in young women. Atherosclerosis risk factors in female youngsters (ARFY study). Stroke 40:1063–1069 [im Druck]

    Article  CAS  PubMed  Google Scholar 

  • Knosalla C, Weng YG, Hammerschmidt R, Pasic M, Schmitt-Knosalla I, Grauhan O, Dandel M, Lehmkuhl HB, Hetzer R (2007) Orthotopic heart transplantation in patients with Marfan syndrome. Ann Thorac Surg 83(5):1691–1695

    Article  PubMed  Google Scholar 

  • Koch AE, Haines GK, Rizzo RJ, Radosevich JA, Pope RM, Robinson PG, Pearce WH (1990) Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response. Am J Pathol 137:1199–1213

    CAS  PubMed  PubMed Central  Google Scholar 

  • Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccinini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C (2009) Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat Med 15:97–103

    Article  CAS  PubMed  Google Scholar 

  • Kretschmer G, Teufelsbauer H (2009) Akuter peripherer Arterienverschluß (ALI). www.meduniwien.at

  • Kroger K (2006) Systemische und regionale Fibrinolyse peripherer arterieller Verschlüsse. Hamostaseologie 26:214

    CAS  PubMed  Google Scholar 

  • Kubes P, Suzuki M, Granger DN (1991) Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A 88:4651–4655

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kuhnert SM, Phillips WJ, Davis MD (1999) Lidocaine and mexiletine therapy for erythromelalgia. Arch Dermatol 135(12):1447–1449

    Article  CAS  PubMed  Google Scholar 

  • Kunz R (1980) Aneurysmata bei 35380 Autopsien [Aneurysms in 35,380 autopsies]. Schweiz Med Wochenschr 110:142–148

    CAS  PubMed  Google Scholar 

  • Kyle MV, Belcher G, Hazleman BL (1992) Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud’s phenomenon. J Rheumatol 19(9):1403–1406

    CAS  PubMed  Google Scholar 

  • Larena-Avellaneda A, Debus ES, Daum H, Kindel M, Gross-Fengels W, Imig H (2004) Mycotic aneurysms affecting both lower legs of a patient with Candida endocarditis – endovascular therapy and open vascular surgery. Ann Vasc Surg 18:130–133

    Article  PubMed  Google Scholar 

  • Lederle FA, Nelson DB, Joseph AM (2003) Smokers’ relative risk for aortic aneurysm compared with other smoking-related diseases: a systematic review. J Vasc Surg 38:329–334

    Article  PubMed  Google Scholar 

  • LeRoy EC, Medsger TA (1992) Raynaud’s phenomenon: a proposal for classification. Clin Exp Rheumatol 10(5):485–488

    CAS  PubMed  Google Scholar 

  • Levi N, Schroeder TV (1997) Arteriosclerotic femoral artery aneurysms. A short review. J Cardiovasc Surg 38:335–338

    CAS  Google Scholar 

  • Levien TL (2006) Phosphodiesterase inhibitors in Raynaud’s phenomenon. Ann Pharmacother 40(7–8):1388–1393

    Article  CAS  PubMed  Google Scholar 

  • Lin Z, Kumar A, SenBanerjee S, Staniszewski K, Parmar K, Vaughan DE, Gimbrone MA Jr, Balasubramanian V, García-Cardeña G, Jain MK (2005) Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function. Circ Res 96:e48–e57

    Article  CAS  PubMed  Google Scholar 

  • Ljungberg LU, Persson K (2008) Effect of nicotine and nicotine metabolites on angiotensin-converting enzyme in human endothelial cells. Endothelium 15:239–245

    Article  CAS  PubMed  Google Scholar 

  • Loeys BL, Chen J, Neptune ER, Judge DP, Podowski M, Holm T, Meyers J, Leitch CC, Katsanis N, Sharifi N, Xu FL, Myers LA, Spevak PJ, Cameron DE, De Backer J, Hellemans J, Chen Y, Davis EC, Webb CL, Kress W, Coucke P, Rifkin DB, De Paepe AM, Dietz HC (2005) A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat Genet 37:275–281

    Article  CAS  PubMed  Google Scholar 

  • Loeys BL, Dietz HC, Braverman AC, Callewaert BL, De Backer J, Devereux RB, Hilhorst-Hofstee Y, Jondeau G, Faivre L, Milewicz DM, Pyeritz RE, Sponseller PD, Wordsworth P, De Paepe AM (2010) The revised Ghent nosology for the Marfan syndrome. J Med Genet 47(7):476–485

    Article  CAS  PubMed  Google Scholar 

  • Lopez-Candales A, Holmes DR, Liao S, Scott MJ, Wickline SA, Thompson RW (1997) Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms. Am J Pathol 150:993–1007

    CAS  PubMed  PubMed Central  Google Scholar 

  • Maegdefessel L, Dalman RL, Tsao PS (2014) Pathogenesis of abdominal aortic aneurysms: microRNAs, proteases, genetic associations. Annu Rev Med 65:49–62

    Article  CAS  PubMed  Google Scholar 

  • Maga P, Kuzdzal J, Nizankowski R, Szczeklik A, Sladek K (2007) Long-term effects of thoracic sympathectomy on microcirculation in the hands of patients with primary Raynaud disease. J Thorac Cardiovasc Surg 133(6):1428–1433

    Article  PubMed  Google Scholar 

  • Mahler F, Meier B, Frey R, Bollinger A, Anliker M (1977) Reaction of red blood cell velocity in nailfold capillaries to local cold in patients with vasospastic disease. Bibl Anat 16:155–158

    PubMed  Google Scholar 

  • Mahler F, Saner H, Boss CH, Annaheim M (1987) Local cold exposure for capillaroscopic examination of patients with Raynaud’s syndrome. Microvasc Res 33:422–427

    Article  CAS  PubMed  Google Scholar 

  • Manow ML, Paulsen N, Rybczynski M, Mir T, Bernhardt AM, Treede H, Ohm G, Fuisting B, Rehder U, Meier F, Vogler M, Meinertz T, Overlack K, von Kodolitsch Y (2010) Analysis of costs and profits of ambulatory care of Marfan patients after initiation of a novel German legal directive (section sign 116 b SGB V). Med Klin (Munich) 105(8):529–537

    Article  Google Scholar 

  • Marcucci M et al (2007) The role of cross-over bypass graft in the treatmment of acute ischemia of the lower limb. G Chir 28:277–280

    CAS  PubMed  Google Scholar 

  • Marfan Hilfe (Deutschland) e.V. (2007) Marfan-Syndrom: Ein Ratgeber für Patienten, Angehörige und Betreuende. Steinkopff, Darmstadt

    Book  Google Scholar 

  • Maricq HR, Spencer-Green G, LeRoy EC (1975) Abnormal capillary patterns and systemic disease in scleroderma (progressive systemic sclerosis). Bibl Anat 13:248–249

    CAS  PubMed  Google Scholar 

  • Maricq HR, LeRoy EC, D’Angelo WA, Medsger TA, Rodnan GP, Sharp GC, Wolfe JF (1980) Diagnostic potential of in vivo capillary microscopy in scleroderma and related disorders. Arthritis Rheum 23(2):183–189

    Article  CAS  PubMed  Google Scholar 

  • Meli M, Gitzelmann G, Koppensteiner R, Amann-Vesti BR (2006) Predictive value of nailfold capillaroscopy in patients with Raynaud’s phenomenon. Clin Rheumatol 25(2):153–158

    Article  PubMed  Google Scholar 

  • Milewicz DM, Guo DC, Tran-Fadulu V, Lafont AL, Papke CL, Inamoto S, Kwartler CS, Pannu H (2008) Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction. Annu Rev Genomics Hum Genet 9:283–302

    Article  CAS  PubMed  Google Scholar 

  • Miller DC (2003) Valve-sparing aortic root replacement in patients with the Marfan syndrome. J Thorac Cardiovasc Surg 125(4):773–778

    Article  PubMed  Google Scholar 

  • Miller DV, Isotalo PA, Weyand CM, Edwards WD, Aubry M-C, Tazelaar HD (2006) Surgical pathology of noninfectious ascending aortitis: a study of 45 cases with emphasis on an isolated variant. Am J Surg Pathol 30:1150–1158

    Article  PubMed  Google Scholar 

  • Mizuguchi T, Collod-Beroud G, Akiyama T, Abifadel M, Harada N, Morisaki T, Allard D, Varret M, Claustres M, Morisaki H, Ihara M, Kinoshita A, Yoshiura K, Junien C, Kajii T, Jondeau G, Ohta T, Kishino T, Furukawa Y, Nakamura Y, Niikawa N, Boileau C, Matsumoto N (2004) Heterozygous TGFBR2 mutations in Marfan syndrome. Nat Genet 36:855–860

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Moore WS (2006) Vascular and endovascular surgery: a comprehensive review, 7. Aufl. Saunders Elsevier, Philadelphia

    Google Scholar 

  • Mosorin M, Juvonen J, Biancari F, Satta J, Surcel HM, Leinonen M, Saikku P, Juvonen T (2001) Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study. J Vasc Surg 34:606–610

    Article  CAS  PubMed  Google Scholar 

  • Naqi SA, Khan HM, Akhtar S, Shah TA (2006) Femoral pseudoaneurysm in drug addicts – excision without revascularization is a viable option. Eur J Vasc Endovasc Surg 31:585–587

    Article  CAS  PubMed  Google Scholar 

  • Newman KM, Ogata Y, Malon AM, Irizarry E, Gandhi RH, Nagase H, Tilson MD (1994) Identification of matrix metalloproteinases 3 (stromelysin-1) and 9 (gelatinase B) in abdominal aortic aneurysm. Arterioscler Thromb 14:1315–1320

    Article  CAS  PubMed  Google Scholar 

  • Ni M, Wang Y, Zhang M, Zhang PF, Ding SF, Liu CX, Liu XL, Zhao YX, Zhang Y (2009) Atherosclerotic plaque disruption induced by stress and lipopolysaccharide in apolipoprotein E knockout mice. Am J Physiol Heart Circ Physiol 296(5):H1598–H1606

    Article  CAS  PubMed  Google Scholar 

  • Nishio E, Fukushima K, Shiozaki M et al (1996) Nitric oxide donor SNAP induces apoptosis in smooth muscle cells through cGMP-independent mechanism. Biochem Biophys Res Commun 221:163–168

    Article  CAS  PubMed  Google Scholar 

  • Nordon IM, Hinchliffe RJ, Holt PJ, Morgan R, Jahangiri M, Loftus IM, Thompson MM (2009) Endovascular management of chronic aortic dissection in patients with Marfan syndrome. J Vasc Surg 50(5):987–991

    Article  PubMed  Google Scholar 

  • Norgren L, Watt W, Dormandy J, Nehler M, Harris K, Fowkes F (2007) Inter-society consensus for the management of peripheral arterial disease (TASC II). Eur J Vasc Endovasc Surg 33(Suppl 1):1–75

    Article  Google Scholar 

  • Norwood MG, Lloyd GM, Moore S, Patel N, Panditi S, Sayers RD (2004) The changing face of femoral artery false aneurysms. Eur J Vasc Endovasc Surg 27:385–388

    Article  CAS  PubMed  Google Scholar 

  • Ohman MK, Shen Y, Obimba CI, Wright AP, Warnock M, Lawrence DA, Eitzman DT (2008) Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 117:798–805

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Otto F (1996) Femorocrurale Gefäßrekonstruktion bei fortgeschrittener peripherer arterieller Verschlußerkrankung. Inauguraldissertation, Lübeck

    Google Scholar 

  • Ouriel K, Shorten CK, DeWeese JA, Green RM, Francis CW, Azodo MV, Gutierrez OH, Manzione JV, Cox C, Marder VJ (1994) A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia. J Vasc Surg 19(6):1021–1030

    Article  CAS  PubMed  Google Scholar 

  • Ouriel K, Veith FJ, Sasahara AA (1998) A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or peripheral arterial surgery (TOPAS) investigators. N Engl J Med 338(16):1105–1111

    Article  CAS  PubMed  Google Scholar 

  • Pacifico L et al (2008) Nonalcoholic fatty liver disease and carotid atherosclerosis in children. Pediatr Res 63:423–427

    Article  CAS  PubMed  Google Scholar 

  • Park YM, Febbraio M, Silverstein RL (2009) CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima. J Clin Invest 119:136–145

    CAS  PubMed  Google Scholar 

  • Parmar KM, Nambudiri V, Dai G, Larman HB, Gimbrone MA Jr, García-Cardeña G (2005) Statins exert endothelial atheroprotective effects via the KLF2 transcription factor. J Biol Chem 280:26714–26719

    Article  CAS  PubMed  Google Scholar 

  • Parmar KM, Larman HB, Dai G, Zhang Y, Wang ET, Moorthy SN, Kratz JR, Lin Z, Jain MK, Gimbrone MA Jr, García-Cardeña G (2006) Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. J Clin Invest 116:49–58

    Article  CAS  PubMed  Google Scholar 

  • Plate G, Jansson I, Forssell C, Weber P, Oredsson S (2006) Thrombolysis for acute lower limb Ischaemla – a prospective, randomised, multicentre study comparing two strategies. Eur J Vasc Endovasc Surg 31:651–660

    Article  CAS  PubMed  Google Scholar 

  • Ponnuswamy P, Ostermeier E, Schroettle A, Chen J, Huang PL, Ertl G, Nieswandt B, Kuhlencordt PJ (2009) Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase. Am J Pathol 174:2400–2410

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Powell JT, Bashir A, Dawson S, Vine N, Henney AM, Humphries SE, Greenhalgh RM (1990) Genetic variation on chromosome 16 is associated with abdominal aortic aneurysm. Clin Sci (Lond) 78:13–16

    Article  CAS  Google Scholar 

  • Pyeritz RE, McKusick VA (1979) The Marfan syndrome: diagnosis and management. N Engl J Med 300:772–777

    Article  CAS  PubMed  Google Scholar 

  • Rademaker M, Cooke ED, Almond NE, Beacham JA, Smith RE, Mant TG, Kirby JD (1989) Comparison of intravenous infusions of iloprost and oral nifedipine in treatment of Raynaud’s phenomenon in patients with systemic sclerosis: a double blind randomized study. BMJ 298:561–564

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Radomski MW, Palmer RM, Moncada S (1987) The anti-aggregating properties of vascular endothelium: interactions between prostacyclin. Br J Pharmacol 92(3):639–646

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Raghunath M, Nienaber CA, von Kodolitsch Y (1997) 100 Jahre Marfan-Syndrom – eine Bestandsaufnahme. Dtsch Ärztebl 94:A–821–A30

    Google Scholar 

  • Raparia K, Molina CP, Quiroga-Garza G et al (2013) Inflammatory aortic aneurysm: possible manifestation of IgG4-related sclerosing disease. Int J Clin Exp Pathol 6:469–475

    CAS  PubMed  PubMed Central  Google Scholar 

  • Rapp JH, Pan XM, Neumann M, Hong M, Hollenbeck K, Liu J (2008) Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition. Stroke 39:2354–2361

    Article  CAS  PubMed  Google Scholar 

  • Rasmussen TE, Hallett JW Jr, Metzger RL, Richardson DM, Harmsen WS, Goronzy JJ, Weyand CM (1997) Genetic risk factors in inflammatory abdominal aortic aneurysms: polymorphic residue 70 in the HLA-DR B1 gene as a key genetic element. J Vasc Surg 25:356–364

    Article  CAS  PubMed  Google Scholar 

  • Riccardi MT, Chialà A, Lannone F, Grattagliano V, Covelli M, Lapadula G (2007) Treatment of digital ulcers in systemic sclerosis with endothelin-1 receptor antagonist (bosentan). Reumatismo 59(2):135–139

    CAS  PubMed  Google Scholar 

  • Rusch NJ, Shepherd JT, Vanhoutte PM (1981) The effect of profound cooling on adrenergic neurotransmission in canine cutaneous veins. J Physiol 311:57–65

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rustin MH, Almond NE, Beacham JA, Brooks RJ, Jones DP, Cooke ED, Dowd PM (1987) The effect of captopril on cutaneous blood flow in patients with primary Raynaud’s phenomenon. Br J Dermatol 117(6):751–758

    Article  CAS  PubMed  Google Scholar 

  • Rutherford RB (2009) Clinical staging of acute limb ischemia as the basis for choice of revascularization method: when and how to intervene. Semin Vasc Surg 22:5–9

    Article  PubMed  Google Scholar 

  • Rutherford RB, Baker JD, Ernst C et al (1997) Recommended standards for reports dealing with lower extremity Ischemia: revised version. J Vasc Surg 26:517–528

    Article  CAS  PubMed  Google Scholar 

  • Rybczynski M, Koschyk D, Aydin MA, Robinson PN, Brinken T, Franzen O, Berger J, Hofmann T, Meinertz T, von Kodolitsch Y (2007) Tissue Doppler imaging identifies myocardial dysfunction in adults with Marfan syndrome. Clin Cardiol 30:19–24

    Article  PubMed  Google Scholar 

  • Rybczynski M, Koschyk D, Karmeier A, Gessler N, Sheikhzadeh S, Bernhardt AM, Habermann CR, Treede H, Berger J, Robinson PN, Meinertz T, von Kodolitsch Y (2010a) Frequency of sleep apnea in adults with the Marfan syndrome. Am J Cardiol 105(12):1836–1841

    Article  PubMed  Google Scholar 

  • Rybczynski M, Mir TS, Sheikhzadeh S, Bernhardt AM, Schad C, Treede H, Veldhoen S, Groene EF, Kuhne K, Koschyk D, Robinson PN, Berger J, Reichenspurner H, Meinertz T, von Kodolitsch Y (2010b) Frequency and age-related course of Mitral valve dysfunction in the Marfan syndrome. Am J Cardiol 106(7):1048–1053

    Article  PubMed  Google Scholar 

  • S3-Leltlinien zur Diagnostik und Therapie der peripheren arteriellen Verschlusskrankheit (PAVK). AWMF-Register Nr. 065/003 Entwicklungsstufe 3 Deutsche Gesellschaft für Angiologie Gesellschaft für Gefäßmedizin. Bearbeitungsstand 27.4.2009

    Google Scholar 

  • Sakata N, Tashiro T, Uesugi N, Kawara T, Furuya K, Hirata Y, Iwasaki H, Kojima M (2008) IgG4-positive plasma cells in inflammatory abdominal aortic aneurysm: the possibility of an aortic manifestation of IgG4-related sclerosing disease. Am J Surg Pathol 32:553–559

    Article  PubMed  Google Scholar 

  • Sato Y, Hatakeyama K, Marutsuka K, Asada Y (2008) Incidence of asymptomatic coronary thrombosis and plaque disruption: comparison of non-cardiac and cardiac deaths among autopsy cases. Thromb Res 124(1):19–23

    Article  PubMed  CAS  Google Scholar 

  • Schwarzberg H (1998) Lokale Fibrinolyse peripher arterieller Gefäßverschlüsse. Fortschr Röntgenstr 169:227–235

    Article  Google Scholar 

  • SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA Jr, García-Cardeña G, Jain MK (2004) KLF2 is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med 199:1305–1315

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shah PK (2009) Inflammation and plaque vulnerability. Cardiovasc Drugs Ther 23:31–40

    Article  CAS  PubMed  Google Scholar 

  • Sheen VL, Jansen A, Chen MH, Parrini E, Morgan T, Ravenscroft R, Ganesh V, Underwood T, Wiley J, Leventer R, Vaid RR, Ruiz DE, Hutchins GM, Menasha J, Willner J, Geng Y, Gripp KW, Nicholson L, Berry-Kravis E, Bodell A, Apse K, Hill RS, Dubeau F, Andermann F, Barkovich J, Andermann E, Shugart YY, Thomas P, Viri M, Veggiotti P, Robertson S, Guerrini R, Walsh CA (2005) Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome. Neurology 64(2):254–262

    Article  CAS  PubMed  Google Scholar 

  • Shekarriz H, Wenk H, Kaiser M, Köppe K, Müller G, Moubayed P (1996) Korrekturbedürftige Veränderungen der Kniekehlenarterie. Indikation, Verfahrenswahl und Ergebnisse. Gefässchirurgie 1:225–230

    Google Scholar 

  • Shibamura H, Olson JM, van Vlijmen-Van Keulen C, Buxbaum SG, Dudek DM, Tromp G, Ogata T, Skunca M, Sakalihasan N, Pals G, Limet R, MacKean GL, Defawe O, Verloes A, Arthur C, Lossing AG, Burnett M, Sueda T, Kuivaniemi H (2004) Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13. Circulation 109:2103–2108

    Article  PubMed  Google Scholar 

  • Shores J, Berger KR, Murphy EA, Pyeritz RE (1994) Progression of aortic dilatation and benefit of long-term ß-adrenergic blockade in Marfan’s syndrome. N Engl J Med 330:1335–1341

    Article  CAS  PubMed  Google Scholar 

  • Shteinberg D, Halak M, Shapiro S, Kinarty A, Sobol E, Lahat N, Karmeli R (2000) Abdominal aortic aneurysm and aortic occlusive disease: a comparison of risk factors and inflammatory response. Eur J Vasc Endovasc Surg 20:462–465

    Article  CAS  PubMed  Google Scholar 

  • Silverman DI, Burton KJ, Gray J, Bosner MS, Kouchoukos NT, Roman MJ, Boxer M, Devereux RB, Tsipouras P (1995) Life expectancy in the Marfan syndrome. Am J Cardiol 175:157–160

    Article  Google Scholar 

  • Smith CD, McKendry RVR (1982) Controlled trial of nifedipine in the treatment of Raynaud’s phenomon. Lancet 2:1299–1301

    Article  CAS  PubMed  Google Scholar 

  • Sommer G et al (2009) Secretory products form human adiocytes stimulate proinflammatory cytokine secretion from human endothelial cells. J Cell Biochem 106:729–737

    Article  CAS  PubMed  Google Scholar 

  • Spalding KL et al (2008) Dynamics of fat cell turnover in humans. Nature 453:783–787

    Article  CAS  PubMed  Google Scholar 

  • Stanley JC (2002) Mesenteric arterial occlusive and aneurysmal disease. Cardiol Clin 20(611–22):vii

    Google Scholar 

  • Steinberger J, Daniels SR, Eckel RH, Hayman L, Lustig RH, McCrindle B, Mietus-Snyder ML, American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young, Council on Cardiovascular Nursing, Council on Nutrition, Physical Activity, and Metabolism (2009) Progress and challenges in metabolic syndrome in children and adolescents: a scientific statement from the American heart association atherosclerosis, hypertension, and obesity in the young committee of the council on cardiovascular disease in the young; council on cardiovascular nursing; and council on nutrition, physical activity, and metabolism. Circulation 119:628–647

    Article  PubMed  Google Scholar 

  • STILE (1994) Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial. Ann Surg 220(3):251–266

    Article  Google Scholar 

  • Stone JR (2011) Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease. Curr Opin Rheumatol 23:88–94

    Article  CAS  PubMed  Google Scholar 

  • Svensson LG, Kouchoukos NT, Miller DC, Bavaria JE, Coselli JS, Curi MA, Eggebrecht H, Elefteriades JA, Erbel R, Gleason TG, Lytle BW, Mitchell RS, Nienaber CA, Roselli EE, Safi HJ, Shemin RJ, Sicard GA, Sundt TM 3rd, Szeto WY, Wheatley GH 3rd (2008) Expert consensus document on the treatment of descending thoracic aortic disease using endovascular stent-grafts. Ann Thorac Surg 85(1 Suppl):S1–S41

    Article  PubMed  Google Scholar 

  • Szabo Z, Crepeau MW, Mitchell AL, Stephan MJ, Puntel RA, Yin Loke K, Kirk RC, Urban Z (2006) Aortic aneurysmal disease and cutis laxa caused by defects in the elastin gene. J Med Genet 43(3):255–258

    Article  CAS  PubMed  Google Scholar 

  • Tabas I (2009) Macrophage apoptosis in atherosclerosis: consequences on plaque progression and the role of endoplasmic reticulum stress. Antioxid Redox Signal 11(9):2333–2339

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Takagi H, Manabe H, Kawai N, Goto SN, Umemoto T (2009) Circulating matrix metalloproteinase-9 concentrations and abdominal aortic aneurysm presence: a meta-analysis. Interact Cardiovasc Thorac Surg 9:437–440

    Article  PubMed  Google Scholar 

  • Tepe G, Hopfenzitz C, Dietz K, Wiskirchen J, Heller S, Ouriel K, Ziemer G, Claussen CD, Duda SH (2006) Peripheral arteries: treatment with antibodies of platelet receptors and reteplase for thrombolysis-APART trial. Radiology 239(3):892–900

    Article  PubMed  Google Scholar 

  • Thompson RW, Curci JA, Ennis TL et al (2006) Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds. Ann N Y Acad Sci 1085:59–73

    Article  CAS  PubMed  Google Scholar 

  • Tiek J, Fourneau I, Daenens K, Nevelsteen A (2009) The role of thrombolysis in acute infrainguinal bypass occlusion: a prospektive nonrandomized controlled study. Ann Vasc Surg 23(2):179–185

    Article  PubMed  Google Scholar 

  • Tosi S, Marchesoni A, Messina K, Bellintani C, Sironi G, Faravelli C (1987) Treatment of Raynaud’s phenomenon with captopril. Drugs Exp Clin Res 13(1):37–42

    CAS  PubMed  Google Scholar 

  • Tousoulis D, Briasoulis A, Papageorgiou N, Antoniades C, Stefanadis C (2008) Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes. Trends Mol Med 14:441–449

    Article  CAS  PubMed  Google Scholar 

  • Urbonavicius S, Urbonaviciene G, Honore B, Henneberg EW, Vorum H, Lindholt JS (2008) Potential circulating biomarkers for abdominal aortic aneurysm expansion and rupture – a systematic review. Eur J Vasc Endovasc Surg 36:273–280, discussion 281–2

    Article  CAS  PubMed  Google Scholar 

  • Vaglio A, Buzio C (2005) Chronic periaortitis: a spectrum of diseases. Curr Opin Rheumatol 17:34–40

    Article  PubMed  Google Scholar 

  • Vaglio A, Greco P, Corradi D, Palmisano A, Martorana D, Ronda N, Buzio C (2006) Autoimmune aspects of chronic periaortitis. Autoimmun Rev 5:458–464

    Article  PubMed  Google Scholar 

  • van de Laar IM, Oldenburg RA, Pals G, Roos-Hesselink JW, de Graaf BM, Verhagen JM, Hoedemaekers YM, Willemsen R, Severijnen LA, Venselaar H, Vriend G, Pattynama PM, Collee M, Majoor-Krakauer D, Poldermans D, Frohn-Mulder IM, Micha D, Timmermans J, Hilhorst-Hofstee Y, Bierma-Zeinstra SM, Willems PJ, Kros JM, Oei EH, Oostra BA, Wessels MW, Bertoli-Avella AM (2011) Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. Nat Genet 43:121–126

    Article  PubMed  CAS  Google Scholar 

  • Verloes A, Sakalihasan N, Koulischer L, Limet R (1995) Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees. J Vasc Surg 21:646–655

    Article  CAS  PubMed  Google Scholar 

  • Vine N, Powell JT (1991) Metalloproteinases in degenerative aortic disease. Clin Sci (Lond) 81:233–239

    Article  CAS  Google Scholar 

  • von Kodolitsch Y, Rybczinsky M (2004) Cardiovascular aspects of the Marfan syndrome – a systematic review. In: Robinson PN, Godfrey M (Hrsg) Marfan syndrome: a primer for clinicians and scientists. Eurekah.com and Kluwer Academic/Plenum Publishers, New York, S 45–69

    Chapter  Google Scholar 

  • von Kodolitsch Y, Rybczynski M (2006) Marfan-Syndrom: Sport und Fitness. In: Marfan-Syndrom. Ein Ratgeber für Patienten, Angehörige und Betreuende. Marfan Hilfe (Deutschland) e.V. Steinkopff, Darmstadt

    Google Scholar 

  • von Kodolitsch Y, Raghunath M, Karck M, Haverich A, Nienaber CA (1998) The Marfan syndrome: therapeutic approach to cardiovascular manifestations. Z Kardiol 87:173–184

    Article  Google Scholar 

  • von Kodolitsch Y, Rybczynski M, Trivic V, Hofmann T, Meinertz T (2002) In Kompetenzzentren behandeln: Lebensqualität und Lebenserwartung beim Marfan-Syndrom verbessern. Klinikarzt 31:201–206

    Google Scholar 

  • von Kodolitsch Y, Arslan-Kirchner M, Vogler M, Rybczynski M (2008a) Das Marfan-Syndrom – eine Übersicht. Internist Prax 48:233

    Google Scholar 

  • von Kodolitsch Y, Rybczynski M, Detter C, Robinson PN (2008b) Diagnosis and management of Marfan syndrome. Future Cardiol 4(1):85–96

    Article  Google Scholar 

  • von Kodolitsch Y, Rybczynski M, Bernhardt A, Mir TS, Treede H, Dodge-Khatami A, Robinson PN, Sheikhzadeh S, Reichenspurner H, Meinertz T (2010) Marfan syndrome and the evolving spectrum of heritable thoracic aortic disease: do we need genetics for clinical decisions? Vasa 39(1):17–32

    Article  Google Scholar 

  • Wang Y, Ait-Oufella H, Herbin O et al (2010) TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice. J Clin Invest 120:422–432

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wang Q, Liu Z, Ren J et al (2015) Receptor-interacting protein kinase 3 contributes to abdominal aortic aneurysms via smooth muscle cell necrosis and inflammation. Circ Res 116:600–611

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wenk H (1998) Akuter Arterienverschluß bei arteriosklerotisch vorgeschädigtem Gefäß. Chirurg 69:585

    Article  CAS  PubMed  Google Scholar 

  • Wenk H (2000) Die lokoregionale Lyse – heute eine Conditio sine qua non? In: Metz L, Kortmann H (Hrsg) Hersfelder Gefäßdialog 1998. Steinkopf, Darmstadt

    Google Scholar 

  • Wenk H (2001) Abdominalgefäße. In: Hartel W, Keminger K, Rehner M, Reith HB, Schreiber HW (Hrsg) Visceralchirurgie. Einhorn, Reinbek bei Hamburg

    Google Scholar 

  • Wenk H, Schmid A (2008) Gefäßchirurgie. In: Henne-Bruns D, Dürig M, Kremer B (Hrsg) Chirurgie. Thieme, Stuttgart

    Google Scholar 

  • Weyand CM, Wagner AD, Bjornsson J, Goronzy JJ (1996) Correlation of the topographical arrangement and the functional pattern of tissue-infiltrating macrophages in giant cell arteritis. J Clin Invest 98:1642–1649

    Article  PubMed  PubMed Central  Google Scholar 

  • Wigley FM, Wise RA, Seibold JR, McCloskey DA, Kujala G, Medsger TA Jr, Steen VD, Varga J, Jimenez S, Mayes M, Clements PJ, Weiner SR, Porter J, Ellman M, Wise C, Kaufman LD, Williams J, Dole W (1994) Intravenous iloprost infusion in patients with Raynaud phenomenon secondary to systemic sclerosis. A multicenter, placebo-controlled, double-blind study. Ann Intern Med 120(3):199–206

    Article  CAS  PubMed  Google Scholar 

  • Wilson AM, Cooke P (2007) L-arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation 116:188–195

    Article  CAS  PubMed  Google Scholar 

  • Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, Bolger A, Cabell CH, Takahashi M, Baltimore RS, Newburger JW, Strom BL, Tani LY, Gerber M, Bonow RO, Pallasch T, Shulman ST, Rowley AH, Burns JC, Ferrieri P, Gardner T, Goff D, Durack DT (2007) Prevention of infective endocarditis: guidelines from the American heart association: a guideline from the American heart association rheumatic fever, endocarditis, and Kawasaki disease committee, council on cardiovascular disease in the young, and the council on clinical cardiology, council on cardiovascular surgery and anesthesia, and the quality of care and outcomes research interdisciplinary working group. Circulation 116(15):1736–1754

    Article  PubMed  Google Scholar 

  • Wilson WR, Choke EC, Dawson J, Loftus IM, Thompson MM (2008) Plasma matrix metalloproteinase levels do not predict tissue levels in abdominal aortic aneurysms suitable for elective repair. Vascular 16:248–252

    Article  PubMed  Google Scholar 

  • Yusuf K, Murat B, Unal A, Ulku K, Taylan K, Ozerdem O, Erdal Y, Tahsin Y (2007) Inflammatory abdominal aortic aneurysm: predictors of long-term outcome in a case–control study. Surgery 142:123 (Kommentar in Surgery 143: 300)

    Google Scholar 

  • Zeller T, Rastan A, Schwarzwalder U et al (2004) Percutaneous peripheral atherectomy of femoropopliteal stenoses using a new-generation device: six-month results from a single-center experience. J Endovasc Ther 11:676–685

    Article  PubMed  Google Scholar 

  • Zucker S, Jian C (2010) Matrix metalloproteinases and cancer cell invasion/metastasis. In: Bagley RG (Hrsg) The tumor microenvironment (cancer drug discovery and development). Springer, Berlin/Heidelberg/New York, S 531–554

    Google Scholar 

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Authors and Affiliations

  1. Klinik und Poliklinik für Gefäßmedizin, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland

    Axel Larena-Avellaneda

  2. Klinik und Poliklinik für Gefäßmedizin, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland

    Sebastian Debus

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  1. Axel Larena-Avellaneda
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  2. Sebastian Debus
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Correspondence to Axel Larena-Avellaneda or Sebastian Debus .

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  1. Allgemeines Krankenhaus Harburg, Hamburg, Germany

    Eike Sebastian Debus

  2. Radiologie, Allgemeines Krankenhaus Harburg Abt. Diagnostische und Interventionelle, Hamburg, Germany

    Walter Gross-Fengels

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Larena-Avellaneda, A., Debus, S. (2015). Aneurysmatische Gefäßerkrankungen: Terminologie, Ätiologie und Lokalisation. In: Debus, E., Gross-Fengels, W. (eds) Operative und interventionelle Gefäßmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45856-3_15-1

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