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Intensive Chemotherapy with Autologous Bone Marrow Transplantation in Small Cell Carcinoma of the Lung

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Small Cell Lung Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 97))

Abstract

In spite of improvements in response rate with combination chemotherapy, median survival is poor in both limited and extensive disease. The best figures for median survival are 18 months in limited disease and 12 months in extensive disease. In large trials, where less selection may have taken place, the survival figures are worse, usually something like 15 months and 9 months, respectively. The adoption of the strategy of using “non-cross-resistant” chemotherapy has made little impact on these dismal figures. Approximately 20% of patients with limited disease will live 2 years from diagnosis, representing 5% of all patients. Furthermore, relapses are frequently seen beyond 2 years.

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Authors and Affiliations

  1. Department of Medical Oncology, Guy’s Hospital, St. Thomas Street, London, SE1, 9RT, England

    P. G. Harper & R. L. Souhami

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  1. P. G. Harper
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  2. R. L. Souhami
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Editors and Affiliations

  1. Innere Klinik und Poliklinik (Tumorforschung) Westdeutsches Tumorzentrum, Universitätsklinikum Essen, Hufelandstrasse 55, 4300, Essen, Federal Republic of Germany

    Siegfried Seeber

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© 1985 Springer-Verlag Berlin · Heidelberg

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Harper, P.G., Souhami, R.L. (1985). Intensive Chemotherapy with Autologous Bone Marrow Transplantation in Small Cell Carcinoma of the Lung. In: Seeber, S. (eds) Small Cell Lung Cancer. Recent Results in Cancer Research, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82372-5_13

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  • DOI: https://doi.org/10.1007/978-3-642-82372-5_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82374-9

  • Online ISBN: 978-3-642-82372-5

  • eBook Packages: Springer Book Archive

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