Abstract
Systemic fungal infections are diagnosed at an increasing frequency during intensive chemotherapy for acute leukemias. This observation may be due to earlier diagnoses but also to more intensive antileukemic and antimicrobial chemotherapy. Hence, antifungal therapy is applied to patients with fever of unknown origin after nonresponse to antibiotic combination treatment. The other use of antifungal agents, however, may be hampered by a possible myelosuppressive effect, especially of 5-flucytosine, which may be more pronounced following intensive antileukemic treatment.
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© 1990 Springer-Verlag Berlin Heidelberg
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Essink, M.E., Hiddemann, W., von Eiff, M., Büchner, T., van de Loo, J. (1990). Effect of Antifungal Therapy on Hematological Recovery After Intensive Antileukemic Chemotherapy. In: Büchner, T., Schellong, G., Hiddemann, W., Ritter, J. (eds) Acute Leukemias II. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74643-7_100
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DOI: https://doi.org/10.1007/978-3-642-74643-7_100
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-50984-4
Online ISBN: 978-3-642-74643-7
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