Abstract
Insulin and glucagon are generally acknowledged to be the most important hormones responsible for the moment-to-moment control of plasma glucose concentrations in man [41]. This is due to their immediate antagonistic effects on the liver; insulin suppresses hepatic glucose output and glucagon stimulates hepatic glucose output. Moreover, secretion of these hormones is reciprocally regulated by glucose; an increase in arterial glucose stimulates insulin secretion and suppresses glucagon secretion, whereas a decrease in arterial glucose suppresses insulin secretion and stimulates glucagon secretion [15].
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© 1989 Springer-Verlag Berlin Heidelberg
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Gerich, J.E. (1989). Abnormal Glucagon Secretion in Type 2 (Noninsulin-Dependent) Diabetes Mellitus: Causes and Consequences. In: Creutzfeldt, W., Lefèbvre, P.J. (eds) Diabetes Mellitus: Pathophysiology and Therapy. Bayer AG Centenary Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74255-2_10
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DOI: https://doi.org/10.1007/978-3-642-74255-2_10
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