Abstract
Red cell acid phosphatase (ACP1) is well established as a useful genetic marker in population studies, in paternity testing, and in the forensic analysis of bloodstains. One interesting biochemical property of this marker is its striking activity increase in the presence of certain alcohols (1–3). This property has been exploited to enhance the sensitivity of ACP1 detection in electrophoretic typing systems (4). We describe here important features of this enhancement phenomenon.
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References
Tsuboi KK, Hudson PB (1953) “Acid phosphatase. I. Human red cell phosphomono-esterase; general properties.” Arch Biochem Biophys 43: 339–357.
Luffman JE, Harris H (1967) “A comparison of some properties of human red cell acid phosphatase in different phenotypes.” Ann Hum Genet 30: 387–401.
Tanizaki MM, Bittencourt HMS, Chaimovich H (1977) “Activation of low molecular weight acid phosphatase from bovine brain by purines and glycerol.” Biochem Biophys Acta 43: 116–123.
Sensabaugh GF, Golden VL (1976) “Erythrocyte acid phosphatase typing on starch gels containing glycerol.” Forensic Serology News 2: 1–2.
Swallow DM, Povey S, Harris H (1973) “Activity of the red ”cell“ acid phosphatase locus in other tissues.” Ann Hum Genet 37: 31–38.
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© 1986 Springer-Verlag Berlin Heidelberg
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Golden, V.L., Sensabaugh, G.F. (1986). Characterization of the Phosphotransferase Activity of Red Cell Acid Phosphatase (ACP1). In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_25
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DOI: https://doi.org/10.1007/978-3-642-71150-3_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16500-2
Online ISBN: 978-3-642-71150-3
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