Abstract
Despite the enormous number of publications on the subject, there is little solid evidence in man for tumour specific antigens which are both antigenic and immunogenic compared with the ease to which such antigens have been demonstrated for transplantable tumours in experimental animals. The failure to demonstrate such antigens in a recent study of spontaneously occurring tumours in laboratory mice has been interpreted as evidence against the existence of tumour antigens in spontaneous tumours in man. Such data cannot exclude the possibility that there may be weakly immunogenic antigens undetected by the systems under test.
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© 1979 Springer-Verlag Berlin Heidelberg
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Oliver, R.T.D., Lee, S.K. (1979). Histocompatibility Antigens and T Cell Responses to Leukemia Antigens. In: Neth, R., Gallo, R.C., Hofschneider, PH., Mannweiler, K. (eds) Modern Trends in Human Leukemia III. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67057-2_48
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DOI: https://doi.org/10.1007/978-3-642-67057-2_48
Publisher Name: Springer, Berlin, Heidelberg
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