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Transcytosis of IgG from the Basolateral to the Apical Membrane of Human Thyrocytes in Autoimmune Thyroid Disease

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Thyroid Pathology

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 91))

Abstract

The thyroid is affected by one of the most common organ-specific autoimmune diseases in humans. Three major autoantigens are involved in thyroid autoimmune disease: thyroglobulin (TG), thyroid peroxidase (TPO), and thyroid-stimulating hormone (TSH) receptor. Both hyperthyroidism and the development of goitre in Graves’ disease are caused by stimulating autoantibodies against TSH receptors. Autoantibodies against TG and TPO can be detected in Graves’ disease and Hashimoto’s thyroiditis.

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Authors
  1. K. P. Zimmer
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  2. K. W. Schmid
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  3. W. Böcker
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  4. G. F. W. Scheumann
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  5. H. Dralle
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  6. J. Brämswig
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  7. E. Harms
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Editor information

Editors and Affiliations

  1. Gerhard Domagk Institute of Pathology, University of Münster/Westfalia, Domagkstrasse. 17, 48149, Münster, Germany

    Kurt W. Schmid  & Werner Böcker  & 

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© 1997 Springer-Verlag Berlin Heidelberg

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Zimmer, K.P. et al. (1997). Transcytosis of IgG from the Basolateral to the Apical Membrane of Human Thyrocytes in Autoimmune Thyroid Disease. In: Schmid, K.W., Böcker, W. (eds) Thyroid Pathology. Current Topics in Pathology, vol 91. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60531-4_9

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  • DOI: https://doi.org/10.1007/978-3-642-60531-4_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64446-7

  • Online ISBN: 978-3-642-60531-4

  • eBook Packages: Springer Book Archive

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