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Protoanemonin

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Part of the book series: Antibiotics ((ANTIBIOTICS,volume 1))

Abstract

Protoanemonin is an antibiotic substance produced mainly by species of Ranunculaceae. Reports of its presence are in the following references: Boas (1934), Zechner and Wohlmuth (1954), Kipping (1935), Shearer (1938), Baer et al. (1946), Herz et al. (1951), Bernard and Metzger (1960) and Tashkov et al. (1961).

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References

  • Asahina, Y., and A. Fujita: Synthesis and constitution of anemonin. J. Pharm. Soc. Japan 455, 1 (1920). Chem. Abstr. 14, 1384 (1920).

    Google Scholar 

  • Baer, H., M. Holden, and B. C. Seegal: The nature of the antibacterial agent from Anemone Pulsatilla. J. Biol. Chem. 162, 65 (1946).

    PubMed  CAS  Google Scholar 

  • Bernard, M., and M. J. Metzger: Antibiotic substances from Ranunculaceae. Proc. Indiana Acad. Sci. 70, 83 (1960).

    CAS  Google Scholar 

  • Boas, F.: Contributions to the operating physiology of native plants. I. Ber. deut. botan. Ges. 52, 126 (1934). Chem. Abstr. 28, 3443 (1934).

    CAS  Google Scholar 

  • Boas, F., and R. Steube: Über die Wirkung von Anemonin auf Mikroorganismen. Biochem. Z. 279, 417 (1935).

    CAS  Google Scholar 

  • Brodersen, R., and A. Kjaer: The antibacterial action and toxicity of some unsaturated lactones. Acta Pharmacol. Toxicol. 2, 109 (1946).

    Article  Google Scholar 

  • Cavallito, C. J., and J. H. Bailey: Preliminary note on the inactivation of antibiotics. Science 100, 390 (1944).

    Article  PubMed  CAS  Google Scholar 

  • Erickson, R. O.: Protoanemonin as a mitotic inhibitor. Science 108, 533 (1948).

    Article  PubMed  CAS  Google Scholar 

  • Erickson, R. O., and G. U. Rosen: Cytological effects of protoanemonin on the root tip of Zea mays. Ann. J. Bot. 36, 317 (1949).

    Article  CAS  Google Scholar 

  • Herz, W., A. L. Pates, and G. C. Madsen: The antimicrobial principle of Clematis dioscoreifolia. Science 114, 206 (1951).

    Article  PubMed  CAS  Google Scholar 

  • Hill, R., and R. VAN HEYNINGEN: Ranunculin: The precursor of the vesicant substance of the buttercup. J. Chem. Soc. 49, 332 (1951).

    CAS  Google Scholar 

  • Holden, M., B. C. Seegal, and H. Baer: Range of antibiotic activity of protoanemonin. Proc. Soc. Exptl. Biol. Med. 66, 54 (1947).

    CAS  Google Scholar 

  • Kipping, F. B.: Lactone of γ-hydroxyvinylacrylic acid, protoanemonin. Biochem. J. 1935, 1145.

    Google Scholar 

  • Mccawley, E. L., B. A. Rubin, and N. J. Giacomino: A preliminary survey of certain lactone antibiotics. Federation Proc. 5, 191 (1946).

    CAS  Google Scholar 

  • Moriarty, R. M., C. R. Romain, I. L. Karle, and J. Karle: The structure of anemonin. J. Am. Chem. Soc. 87, 3251 (1965).

    Article  CAS  Google Scholar 

  • Rotter, K., and W. Gruber: Antibiotic activity and toxicity of protoanemonin. Mikrobiol. Hochschule Bodenkult. 3, 108 (1949). Chem. Abstr. 47, 7094e (1953).

    CAS  Google Scholar 

  • Shearer, G. D.: Some observations on the poisonous properties of buttercups. Vet. J. 94, 22 (1938).

    CAS  Google Scholar 

  • Thimann, K. V., and W. D. Bonner: Inhibition of plant growth by protoanemonin and coumarin and its prevention by BAL. Proc. Natl. Acad. Sci. U.S. 35, 272 (1949).

    Article  CAS  Google Scholar 

  • Toshkov, As., V. Ivanov, U. Sobeva, T. Gancheva, S. Pangelova, and V. Toneva: Antibacterial, antiviral, antitoxic, and cytopathogenic properties of protoanemonin and anemonin. Antibiotiki 6, 918 (1961). Chem. Abstr. 56, 15612b (1962).

    PubMed  CAS  Google Scholar 

  • Zechner, L., and H. Wohlmuth: Anemonin and protoanemonin. I. New method of isolation of anemonin from Ranunculus acerL. Sci. Pharm. 22, 74 (1954a). Chem. Abstr. 48, 13169c (19

    CAS  Google Scholar 

  • Zechner, L., and H. Wohlmuth: Anemonin and protoanemonin. II. Vermicidal action. Sci. Pharm. 22, 90 (1954b). Chem. Abstr. 48, 13l69d (1954).

    CAS  Google Scholar 

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© 1967 Springer-Verlag Berlin · Heidelberg

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Caltrider, P.G. (1967). Protoanemonin. In: Gottlieb, D., Shaw, P.D. (eds) Mechanism of Action. Antibiotics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46051-7_55

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  • DOI: https://doi.org/10.1007/978-3-642-46051-7_55

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46053-1

  • Online ISBN: 978-3-642-46051-7

  • eBook Packages: Springer Book Archive

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