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This chapter reviews methodologies that monitor the spatial distribution of cerebral metabolic, hemodynamic, electrical, or magnetic reactions by which areas of the brain are identified that are active during the processing and perception of experimentally induced or clinical pain originating in the human skin.
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Functional imaging techniques applied for the study of cutaneous pain are positron emission tomography (PET), functional magnetic resonance imaging (fMRI), multi-lead electroencephalography (EEG), and magnetoencephalography(MEG). PET measures cerebral blood flow, glucose metabolism, or neurotransmitter kinetics. A very small amount of a labeled compound (called the radiotracer) is intravenously injected into the patient or volunteer. During its uptake and decay in the brain, the radionuclide emits a positron, which, after traveling a short distance, “annihilates” with an electron from the surrounding...
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© 2013 Springer-Verlag Berlin Heidelberg
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Lorenz, J. (2013). Functional Imaging of Cutaneous Pain. In: Gebhart, G.F., Schmidt, R.F. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28753-4_1572
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DOI: https://doi.org/10.1007/978-3-642-28753-4_1572
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