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Liver Metastases

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Induction Chemotherapy

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Abstract

The worldwide incidence of cancer is increasing, and with it the incidence of metastatic disease to the liver. The commonest treatable liver metastasis is from cancer of the colon or rectum. Traditionally, only 20–30% of patients presenting with colorectal liver metastases were eligible for surgical resection with curative intent. Refinements in imaging, anaesthesia, surgical techniques and chemotherapeutic regimes have led to an expansion in eligibility for resection. Preoperative chemotherapy can downstage tumours for curative resection and results from recent studies are encouraging. Here we provide an overview of the current status of induction chemotherapy for liver metastases.

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Author information

Authors and Affiliations

  1. Department of Surgery, St George Hospital, The University of New South Wales, Pitney Building Level 3, Kogarah, NSW, 2217, Australia

    Miriam Rebecca Habib & David Lawson Morris

Authors
  1. Miriam Rebecca Habib
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  2. David Lawson Morris
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Correspondence to David Lawson Morris .

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Editors and Affiliations

  1. Abt. Onkologische Chirurgie, Medias Klinikum GmbH & Co. KG, Krankenhausstr. 1, Burghausen, 84489, Germany

    Karl Reinhard Aigner

  2. Inkerman Street 16, Mosman, 2088, New South Wales, Australia

    Frederick O. Stephens

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© 2011 Springer-Verlag Berlin Heidelberg

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Habib, M.R., Morris, D.L. (2011). Liver Metastases. In: Aigner, K., Stephens, F. (eds) Induction Chemotherapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18173-3_23

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  • DOI: https://doi.org/10.1007/978-3-642-18173-3_23

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  • Print ISBN: 978-3-642-18172-6

  • Online ISBN: 978-3-642-18173-3

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