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Malassezia

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Pathogenic Yeasts

Part of the book series: The Yeast Handbook ((YEASTHDB))

Abstract

Over the last decade, there has been a big increase in our understanding of many aspects of yeasts of the genus Malassezia. The description of several new species and characterisation of the genetic diversity of several other species has now resulted in 13 recognised species, with others that may be defined in the future. Recent studies have also examined the metabolites that are produced by the species of Malassezia, and how they may be related to the disease with which Malassezia has been associated. Although many studies have sought to associate a particular species with a particular disease, this has been controversial and the pattern that is now emerging is that there may be geographic variations in both commensal flora and also species associated with disease. The role of Malassezia in pityriasis versicolor, seborrhoeic dermatitis and, especially atopic eczema, has been studied, and the complex interactions between the organism and the host are being slowly revealed. As further studies continue, we may finally begin to understand how these organisms can exist on the skin as commensals, with minimum immune stimulation, but in some people they are able to either cause or exacerbate various cutaneous conditions.

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  1. Mycology Reference Centre, Department of Microbiology, Leeds General Infirmary, Leeds, LS1 3EX, UK

    H. Ruth Ashbee

  2. Karolinska Institutet, Department of Medicine Solna, Clinical Allergy Research Unit L2:04, Karolinska University Hospital, Solna, 171 76, Stockholm, Sweden

    Annika Scheynius

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  1. Old Medical School, Leeds General Infirmary, Leeds, LS1 3EX, United Kingdom

    Ruth Ashbee

  2. Div. Investigative Science, Imperial College London, South Kensington Campus, London , SW7 2AZ, United Kingdom

    Elaine M. Bignell

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Ashbee, H.R., Scheynius, A. (2010). Malassezia. In: Ashbee, R., Bignell, E. (eds) Pathogenic Yeasts. The Yeast Handbook. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03150-2_10

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