Overview
- Comprehensive overview on GPCRs and the novel neuropeptides discovered with their help
- Most authors are the original discoverers of the respective novel neuropeptides
- First book to also describe the functional significance of the novel neuropeptides
- Includes supplementary material: sn.pub/extras
Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 46)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms.
The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
Bibliographic Information
Book Title: Orphan G Protein-Coupled Receptors and Novel Neuropeptides
Editors: Olivier Civelli, Qun-Yong Zhou
Series Title: Results and Problems in Cell Differentiation
DOI: https://doi.org/10.1007/978-3-540-78351-0
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-78350-3Published: 13 June 2008
Softcover ISBN: 978-3-642-09705-8Published: 19 October 2010
eBook ISBN: 978-3-540-78351-0Published: 15 May 2008
Series ISSN: 0080-1844
Series E-ISSN: 1861-0412
Edition Number: 1
Number of Pages: XV, 259
Topics: Neurobiology, Pharmacology/Toxicology, Endocrinology, Neurosciences, Cell Biology