Abstract
It is difficult to directly co-register the 3D FMT (Fluorescence Molecular Tomography) image of a small tumor in a mouse whose maximal diameter is only a few mm with a larger CT image of the entire animal that spans about ten cm. This paper proposes a new method to register 2D flat and projected CT image first to facilitate the registration between small 3D FMT images and large CT images. And a novel algorithm Bayesian Iterative Closest Point (BICP) is introduced and validated in 2D affine registration. The visualization of the alignment of the 3D FMT and CT image through 2D registration shows promising results that would lead to automated 3D registration.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Jan, G., David, G.K., Stephen, D.W., Carla, F.B.K., Philip, M.S., Vasilis, N., Tyler, J., Ralph, W.: Use of Gene Expression Profiling to Direct in Vivo Molecular Imaging of Lung Cancer. PNAS 102(40) (2005)
Weissleder, R.: Molecular Imaging: Exploring the Next Frontier (Review). Radiology 212, 609–614 (1999)
Tung, C., Mahmood, U., Bredow, S., et al.: In Vivo Imaging of Proteolytic Enzyme Activity Using a Novel Molecular Reporter. Cancer Res. 60, 4953–4958 (2000)
Ntziachristos, V., Tung, C., Bremer, C., Weissleder, R.: Fluorescence Molecular Tomography Resolves Protease Activity in Vivo. Nat. Med. 8(7), 757–760 (2002)
Ntziachristos, V., Bremer, C., Graves, E.E., Ripoll, J., Weissleder, R.: In Vivo Tomographic Imaging of Near-infrared Fluorescent probes. Mol. Imaging. 1, 82–88 (2002)
Ntziachristos, V., Ripoll, J., Wang, L.V., Weissleder, R.: Looking and Listening to Light: the Evolution of Whole-body Photonic Imaging. Nat. Biotechnol. 23, 313–320 (2005)
Frederik, M., Dirk, V., Paul, S.: Comparative Evaluation of Multiresolution Optimization Strategies for Multimodality Image Registration by Maximization of Mutual Information. Medical Image Analysis 3(4), 373–386 (1999)
Graves, E.E., et al.: A Submillimeter Resolution Fluorescence Molecular Imaging System for Small Animal Imaging. Med. Phys. 30(3), 901–911 (2003)
Barbara, Z., Jan, F.: Image Registration Methods: A Survey. Image and Vision Computing 21, 977–1000 (2003)
Press, W., Teukolsky, S., Vetterling, W., Flannery, B.: Numerical Recipes in C++, 2nd edn. Cambridge University Press, Cambridge (2002)
Rainer, S., Kenneth, P.: Differential Evolution - A Simple and Efficient Adaptive Scheme for Global Optimization over Continuous Spaces. ICSI TECHINCAL Report tr-95-012 (1995)
Kass, M., Witkin, A., Terzopoulos, D.: Snake: Active Contour Models. Int. J. Computer Vision 1(4), 321–331 (1987)
Chenyang, X., Jerry, L.P.: Snakes, Shapes, and Gradient Vector Flow. IEEE Transaction on Image Processing 7(3), 359–369 (1998)
Paul, J.B., Neil, D.M.: A Method for Registration of 3D Shapes. IEEE Transactions on Pattern Analysis and Machine Intelligence 14(2), 239–255 (1992)
Andrieu, C., Freitas, J., Doucet, A.: Robust Full Bayesian Learning for Neural Networks (1999), http://www.cs.berkeley.edu/jfgf/software.html
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 2007 Springer Berlin Heidelberg
About this paper
Cite this paper
Zheng, X., Zhou, X., Sun, Y., Wong, S.T.C. (2007). Registration of 3D FMT and CT Images of Mouse Via Affine Transformation with Bayesian Iterative Closest Points. In: Liu, D., Fei, S., Hou, Z., Zhang, H., Sun, C. (eds) Advances in Neural Networks – ISNN 2007. ISNN 2007. Lecture Notes in Computer Science, vol 4492. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72393-6_135
Download citation
DOI: https://doi.org/10.1007/978-3-540-72393-6_135
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-72392-9
Online ISBN: 978-3-540-72393-6
eBook Packages: Computer ScienceComputer Science (R0)