Skip to main content
SpringerLink
Log in
Book cover

Encyclopedia of Ophthalmology pp 1815–1816Cite as

Toxic Anterior Segment Syndrome

  • Reference work entry
  • First Online:

  • 56 Accesses

Synonyms

TASS

Definition

Sterile inflammatory reaction of unknown incidence that can occur after anterior segment surgery.

Etiology

Administration of solutions of inappropriate chemical composition during anterior segment surgery. Various entities have been shown to cause toxic anterior segment syndrome. These include, but are not limited to, endotoxin; denatured ophthalmic viscosurgical devices; preservatives such as benzalkonium chloride, bisulfites, and metabisulfites; heavy metal residue; fine-matter particulates; and substances introduced into the anterior chamber that are at a pH or concentration that is toxic to the endothelial cells. In addition, residue of materials used in the cleaning and sterilization of ophthalmic instruments are a cause of toxic anterior segment syndrome.

Occurrence

After administration of solutions of inappropriate chemical composition during surgery, a sterile anterior chamber inflammation develops 12–48 h after surgery. Endophthalmitis as a...

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   1,199.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   1,599.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Further Reading

  • Cutler Peck CM, Brubaker J, Clouser S, Danford C, Edelhauser HE, Mamalis N (2010) Toxic anterior segment syndrome: common causes. J Cataract Refract Surg 36(7):1073–1080

    Article  PubMed  Google Scholar 

  • Johnston J (2006) Toxic anterior segment syndrome – more than sterility meets the eye. AORN J 84(6):969–984

    Article  PubMed  Google Scholar 

  • Mamalis N (2010) Toxic anterior segment syndrome update. J Cataract Refract Surg 36(7):1067–1068

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, University of Regensburg Medical Center, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany

    Wolfgang Herrmann

  2. Department of Ophthalmology, Goethe-University Frankfurt am Main, Frankfurt am Main, Germany

    Thomas Kohnen

Authors
  1. Wolfgang Herrmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Thomas Kohnen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Wolfgang Herrmann .

Editor information

Editors and Affiliations

  1. Department of Ophthalmology and Optometry, Medical University Vienna, Vienna, Austria

    Ursula Schmidt-Erfurth

  2. Department of Ophthalmology, Goethe University of Frankfurt am Main, Frankfurt am Main, Germany

    Thomas Kohnen

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Germany

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Herrmann, W., Kohnen, T. (2018). Toxic Anterior Segment Syndrome. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69000-9_341

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69000-9_341

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68292-9

  • Online ISBN: 978-3-540-69000-9

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation