Skip to main content
SpringerLink
Log in

Bioactivity of Essential Oils and Their Components

  • Chapter
Flavours and Fragrances

5.10 Conclusions

The present review demonstrates that EOs and their components have many functional properties and exert their action in mammals as well as in other organisms (insects, fungi, bacteria and viruses). The synergistic effect of EO components is a promising field that could lead to the optimisation of a given bioactivity. This phenomenon has been observed in many activities, such as those of antimicrobials, antioxidants, analgesics and semiochemicals. EOs are complex mixtures of components that show higher activities than their isolated components; their final activities are due to the combine effects of several minor components. Thus, EOs contain multifunctional components that exert their activities through different mechanisms. EOs and their components may have new applications against various diseases of different origins (cancer, fungal, bacterial or viral), because some of these complex diseases require multiple components and multifunctional therapies.

The natural product industry is actively seeking natural therapeutics, preservatives, repellents and other agents that can replace synthetic compounds. The scientific literature has identified new applications and uses of both traditional and exotic EOs. These applications can ultimately assist growers and rural communities in the developing world to increase interest in their products.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Rauha J-P, Remes S, Heinonen M, Hopia A, Kahkonen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P (2000) Int J Food Microbiol 56:3

    Article  CAS  Google Scholar 

  2. Zygadlo JA, Juliani HR (2000) Curr Top Phytochem 3:203

    CAS  Google Scholar 

  3. Anonymous (2003) Alberta Agriculture, Food and Rural Development, Edmonton

    Google Scholar 

  4. Lawrence BM (1993) In: Janick J, Simon JE (eds) New Crops. Wiley, New York, p 620

    Google Scholar 

  5. Simon JE, Juliani HR, Letchamo W, Smith M, Goliath J, Graven E, Lewinsohn E, Lewinsohn D, Deschamps C, Dudareva N, Morales M, Picerksky E, Gang D, Rotter D, Raskin I, Vieira R, Ranarivelo L, Rasoanaivo P, Acqueye D (2002) New Aromatic Essential Oils. 5th National Symposium. New Crops and New Uses: Strength in Diversity, Atlanta, Georgia, 10–13 November

    Google Scholar 

  6. Essawi T, Srour M (2000) J Ethnopharmacol 70:343

    Article  CAS  Google Scholar 

  7. Lee HC, Cheng SS, Chang ST (2005) J Sci Food Agric 85:2047

    Article  CAS  Google Scholar 

  8. Griffin SG, Wyllie SG, Markham JL, Leach DN (1999) Flavour Fragrance J 14:322

    Article  CAS  Google Scholar 

  9. Dorman HJD, Deans SG (2000) J Appl Microbiol 88:308

    Article  CAS  Google Scholar 

  10. Kalemba D, Kunicka A (2003) Curr Med Chem 10:813

    Article  CAS  Google Scholar 

  11. Daferera DJ, Ziogas BN, Polissiou MG (2000) J Agric Food Chem 48:2576

    Article  CAS  Google Scholar 

  12. Gulluce M, Sokmen M, Daferera D, Agar G, Ozkan H, Kartal N, Polissiou M, Sokmen A, Sahin F (2003) J Agric Food Chem 51:3958

    Article  CAS  Google Scholar 

  13. Bagamboula CF, Uyttendaele M, Debevere J (2004) Food Microbiol 21:33

    Article  CAS  Google Scholar 

  14. Ultee A, Bennik MHJ, Moezelaar R (2002) Appl Environ Microb 68:1561

    Article  CAS  Google Scholar 

  15. Lambert RJW, Skandamis PN, Coote PJ, Nychas G-JE (2001) J Appl Microbiol 91:453

    Article  CAS  Google Scholar 

  16. Salgueiro LR, Cavaleiro C, Goncalves MJ, da Cunha AP (2003) Planta Med 69:80

    Article  CAS  Google Scholar 

  17. Tepe B, Daferera D, Sokmen M, Polissiou M, Sokmen A (2004) J Agric Food Chem 52:1132

    CAS  Google Scholar 

  18. Friedman M, Henika PR, Mandrell RE (2002) J Food Protect 65:1545

    CAS  Google Scholar 

  19. Aligiannis N, Kalpoutzakis E, Mitaku S, Chinou IB (2001) J Agric Food Chem 49:4168

    Article  CAS  Google Scholar 

  20. Chang ST, Chen PF, Chang SC (2001) J Ethnopharmacol 77:123

    Article  CAS  Google Scholar 

  21. Ali N, Mohtar M, Shaari K, Rahmanii M, Ali AM, bin Jantan I (2002) J Essent Oil Res 14:135

    CAS  Google Scholar 

  22. Simic A, Sokovic MD, Ristic M, Grujic-Jovanovic S, Vukojevic J, Marin PD (2004) Phytother Res 18:713

    Article  CAS  Google Scholar 

  23. Ranasinghe L, Jayawardena B, Abeywickrama K (2002) Lett Appl Microbiol 35:208

    Article  CAS  Google Scholar 

  24. Wang SY, Chen PF, Chang ST (2005) Bioresource Technol 96:813

    Article  CAS  Google Scholar 

  25. Sokovic M, Tzakou O, Pitarokili D, Couladis M (2002) Nahrung-Food 46:317

    Article  CAS  Google Scholar 

  26. Baydar H, Sagdic O, Ozkan G, Karadogan T (2004) Food Control 15:169

    Article  CAS  Google Scholar 

  27. Aligiannis N, Kalpoutzakis E, Chinou IB, Mitakou S, Gikas E, Tsarbopoulos A (2001) J Agric Food Chem 49:811

    Article  CAS  Google Scholar 

  28. Karaman S, Digrak M, Ravid U, Ilcim A (2001) J Ethnopharmacol 76:183

    Article  CAS  Google Scholar 

  29. Hernandez T, Canales M, Avila JG, Garcia AM, Martinez A, Caballero J, de Vivar AR, Lira R (2005) J Ethnopharmacol 96:551

    Article  CAS  Google Scholar 

  30. Skocibusic M, Bezic N (2004) Phytother Res 18:967

    Article  CAS  Google Scholar 

  31. Biavati B, Ozcan M, Piccagilia R (2004) Ann Microbiol 54:393

    CAS  Google Scholar 

  32. dos Santos FJB, Arimateia J, Lopes D, Cito AMGL, de Oliveira EH, de Lima SG, Reis FD (2004) J Essent Oil Res 16:504

    Google Scholar 

  33. Chorianopoulos N, Kalpoutzakis E, Aligiannis N, Mitaku S, Nychas GJ, Haroutounian SA (2004) J Agric Food Chem 52:8261

    CAS  Google Scholar 

  34. Mirjana S, Nada B (2004) J Essent Oil Res 16:387

    CAS  Google Scholar 

  35. Marino M, Bersani C, Comi G (2001) Int J Food Microbiol 67:187

    Article  CAS  Google Scholar 

  36. Sonboli A, Fakhari A, Kanani MR, Yousefzadi M (2004) Z Naturforsch C 59:777

    CAS  Google Scholar 

  37. Couladis M, Tzakou O, Kujundzic S, Sokovic M, Mimica-Dukic N (2004) Phytother Res 18:40

    Article  CAS  Google Scholar 

  38. Bassole IHN, Ouattara AS, Nebie R, Ouattara CAT, Kabore ZI, Traore SA (2003) Phytochemistry 62:209

    Article  CAS  Google Scholar 

  39. Dadalioglu I, Evrendilek GA (2004) J Agric Food Chem 52:8255

    CAS  Google Scholar 

  40. Tzakou O, Pitarokili D, Chinou IB, Harvala C (2001) Planta Med 67:81

    Article  CAS  Google Scholar 

  41. Cha JD, Jeong MR, Jeong SI, Moon SE, Kim JY, Kil BS, Song YH (2005) Planta Med 71:186

    Article  CAS  Google Scholar 

  42. Tepe B, Donmez E, Unlu M, Candan F, Daferera D, Vardar-Unlu G, Polissiou M, Sokmen A (2004) Food Chem 84:519

    Article  CAS  Google Scholar 

  43. Kalpoutzakis E, Aligiannis N, Mentis A, Mitaku S, Charvala C (2001) Planta Med 67:880

    Article  CAS  Google Scholar 

  44. Mourey A, Canillac N (2002) Food Control 13:289

    Article  CAS  Google Scholar 

  45. Unlu M, Daferera D, Donmez E, Polissiou M, Tepe B, Sokmen A (2002) J Ethnopharmacol 83:117

    Article  CAS  Google Scholar 

  46. Viljoen A, van Vuuren S, Ernst E, Klepser M, Demirci B, Baser H, van Wyk BE (2003) J Ethnopharmacol 88:137

    Article  CAS  Google Scholar 

  47. Kordali S, Cakir A, Mavi A, Kilic H, Yildirim A (2005) J Agric Food Chem 53:1408

    Article  CAS  Google Scholar 

  48. Pitarokili D, Tzakou O, Loukis A, Harvala C (2003) J Agric Food Chem 51:3294

    Article  CAS  Google Scholar 

  49. Belletti N, Ndaguimana M, Sisto C, Guerzoni ME, Lanciotti R, Gardini F (2004) J Agric Food Chem 52:6932

    Article  CAS  Google Scholar 

  50. Araujo C, Sousa MJ, Ferreira MF, Leao C (2003) J Food Protect 66:625

    CAS  Google Scholar 

  51. Ngassapa O, Runyoro DKB, Harvala E, Chinou IB (2003) Flavour Fragrance J 18:221

    Article  CAS  Google Scholar 

  52. Martins AP, Salgueiro L, Goncalves MJ, da Cunha AP, Vila R, Canigueral S, Mazzoni V, Tomi F, Casanova J (2001) Planta Med 67:580

    Article  CAS  Google Scholar 

  53. Tepe B, Sokmen M, Sokmen A, Daferera D, Polissiou M (2005) J Food Eng 69:335

    Article  Google Scholar 

  54. Oumzil H, Ghoulami S, Rhajaoui M, Ilidrissi A, Fkih-Tetouani S, Faid M, Benjouad A (2002) Phytother Res 16:727

    Article  CAS  Google Scholar 

  55. Sibanda S, Chigwada G, Poole M, Gwebu ET, Noletto JA, Schmidt JM, Rea AI, Setzer WN (2004) J Ethnopharmacol 92:107

    Article  CAS  Google Scholar 

  56. Duru ME, Ozturk M, Ugur A, Ceylan O (2004) J Ethnopharmacol 94:43

    Article  CAS  Google Scholar 

  57. Bouzouita N, Kachouri F, Hamdi M, Chaabouni MM, Ben Aissa R, Zgoulli S, Thonart R, Carlier A, Marlier M, Lognay GC (2005) J Essent Oil Res 17:584

    CAS  Google Scholar 

  58. Baser KHC, Demirci B, Demirci F, Kocak S, Akinci C, Malyer H, Guleryuz G (2002) Planta Med 68:941

    Article  CAS  Google Scholar 

  59. Soylu EM, Yigitbas H, Tok FM, Soylu S, Kurt S, Baysal O, Kaya AD (2005) Z Pflanzenk Pflanzen 112:229

    Google Scholar 

  60. Bezic N, Skocibusic M, Dunkic V, Radonic A (2003) Phytother Res 17:1037

    Article  CAS  Google Scholar 

  61. Zhu SY, Yang Y, Yu HD, Yue Y, Zou GL (2005) J Ethnopharmacol 96:151

    Article  CAS  Google Scholar 

  62. Alvarez-Castellanos PP, Bishop CD, Pascual-Villalobos MJ (2001) Phytochemistry 57:99

    Article  CAS  Google Scholar 

  63. Demetzos C, Angelopoulou D, Perdetzoglou D (2002) Biochem Syst Ecol 30:651

    Article  CAS  Google Scholar 

  64. Setzer WN, Vogler B, Schmidt JM, Leahy JG, Rives R (2004) Fitoterapia 75:192

    Article  CAS  Google Scholar 

  65. Tabanca N, Kirimer N, Demirci B, Demirci F, Baser KHC (2001) J Agric Food Chem 49:4300

    Article  CAS  Google Scholar 

  66. Yu HH, Kim YH, Kil BS, Kim KJ, Jeong SI, You YO (2003) Planta Med 69:1159

    Article  CAS  Google Scholar 

  67. Kim KJ, Kim YH, Yu HH, Jeong SI, Cha JD, Kil BS, You YO (2003) Planta Med 69:274

    Article  CAS  Google Scholar 

  68. Senatore F, Formisano C, Arnold NA, Piozzi F (2005) J Essent Oil Res 17:419

    CAS  Google Scholar 

  69. Yu JQ, Lei JC, Yu HD, Cai X, Zou GL (2004) Phytochemistry 65:881

    Article  CAS  Google Scholar 

  70. Iscan G, Kirimer N, Kurkcuoglu M, Husnu CanBaser K, Demirci F (2002) J Agric Food Chem 50:3943

    Article  CAS  Google Scholar 

  71. Viljoen AM, Subramoney S, van Vuuren SF, Baser KHC, Demirci B (2005) J Ethnopharmacol 96:271

    Article  CAS  Google Scholar 

  72. Sonboli A, Eftekhar F, Yousefzadi M, Kanani MR (2005) Z Naturforsch C 60:30

    CAS  Google Scholar 

  73. Delaquis PJ, Stanich K, Girard B, Mazza G (2002) Int J Food Microbiol 74:101

    Article  CAS  Google Scholar 

  74. Vardar-Unlu G, Candan F, Sokmen A, Daferera D, Polissiou M, Sokmen M, Donmez E, Tepe B (2003) J Agric Food Chem 51:63

    Article  CAS  Google Scholar 

  75. bin Jantan I, Yassin MSM, Chin CB, Chen LL, Sim NL (2003) Pharm Biol 41:392

    Google Scholar 

  76. Prashar A, Hili P, Veness RG, Evans CS (2003) Phytochemistry 63:569

    Article  CAS  Google Scholar 

  77. Sokovic MD, Ristic M, Grubisic D (2004) Pharm Biol 42:328

    CAS  Google Scholar 

  78. Staniszewska M, Kula J, Wieczorkiewicz M, Kusewicz D (2005) J Essent Oil Res 17:579

    CAS  Google Scholar 

  79. Oyedeji OA, Afolayan A (2005) S Afr J Bot 71:114

    CAS  Google Scholar 

  80. Parveen M, Hasan MK, Takahashi J, Murata Y, Kitagawa E, Kodama O, Iwahashi H (2004) J Antimicrob Chemother 54:46

    Article  CAS  Google Scholar 

  81. Al-Burtamani SKS, Fatope MO, Marwah RG, Onifade AK, Al-Saidi SH (2005) J Ethnopharmacol 96:107

    Article  CAS  Google Scholar 

  82. Jo C, Park BJ, Chung SH, Kim CB, Cha BS, Byun MW (2004) Food Sci Biotechnol 13:384

    Google Scholar 

  83. Jirovetz L, Buchbauer G, Stoyanova AS, Georgiev EV, Damianova ST (2003) J Agric Food Chem 51:3854

    CAS  Google Scholar 

  84. Haznedaroglu MZ, Karabay U, Zeybek U (2001) Fitoterapia 72:829

    Article  CAS  Google Scholar 

  85. Lis-Balchin M, Ochocka RJ, Deans SG, Asztemborska M, Hart S (1999) J Essent Oil Res 11:393

    CAS  Google Scholar 

  86. Aligiannis N, Kalpoutzakis E, Kyriakopoulou I, Mitaku S, Chinou IB (2004) Flavour Fragrance J 19:320

    Article  CAS  Google Scholar 

  87. Rotman A, Ahumada O, Demo MS, Oliva MD, Turina AV, Lopez ML, Zygadlo JA, (2003) Flavour Fragrance J 18:211

    Article  CAS  Google Scholar 

  88. de Carvalho PM, Rodrigues RFO, Sawaya ACHF, Marques MOM, Shimizu MT (2004) J Ethnopharmacol 95:297

    Article  CAS  Google Scholar 

  89. Canillac N, Mourey A (2001) Food Microbiol 18:261

    Article  CAS  Google Scholar 

  90. Martins AP, Salgueiro LR, Goncalves MJ, da Cunha AP, Vila R, Caniguerl SC (2003) Planta Med 69:77

    Article  CAS  Google Scholar 

  91. Hammer KA, Carson CF, Riley TV (2003) J Appl Microbiol 95:853

    Article  CAS  Google Scholar 

  92. Cakir A, Kordali S, Kilic H, Kaya E (2005) Biochem Syst Ecol 33:245

    Article  CAS  Google Scholar 

  93. Cheng SS, Lin HY, Chang ST (2005) J Agric Food Chem 53:614

    Article  CAS  Google Scholar 

  94. Cakir A, Kordali S, Zengin H, Izumi S, Hirata T (2004) Flavour Fragrance J 19:62

    Article  CAS  Google Scholar 

  95. Juliani HR, Biurrun F, Koroch AR, Oliva MM, Demo MS, Trippi VS, Zygadlo JA (2002) Planta Med 68:762

    Article  CAS  Google Scholar 

  96. Martins AP, Salgueiro UR, Goncalves MJ, Vila R, Canigueral S, Tomi F, Casanova J (2005) J Essent Oil Res 17:239

    CAS  Google Scholar 

  97. Chang ST, Wang SY, Wu CL, Chen PF, Kuo YH (2000) Holzforschung 54:241

    Article  CAS  Google Scholar 

  98. Cheng SS, Wu CL, Chang HT, Kao YT, Chang ST (2004) J Chem Ecol 30:1957

    Article  CAS  Google Scholar 

  99. Inoue Y, Shiraishi A, Hada T, Hirose K, Hamashima H, Shimada J (2004) FEMS Microbiol Lett 237:325

    CAS  Google Scholar 

  100. Wang SY, Wu CL, Chug FH, Chien SC, Kuo YH, Shyur LF, Chang ST (2005) Holzforschung 59:295

    Article  CAS  Google Scholar 

  101. Yayli N, Yasar A, Gulec C, Usta A, Kolayli S, Coskuncelebi K, Karaoglu S (2005) Phytochemistry 66:1741

    Article  CAS  Google Scholar 

  102. Lago JHG, de Avila P, de Aquino EM, Moreno PRH, Ohara MT, Limberger RP, Apel MA, Henriques AT (2004) Flavour Fragrance J 19:448

    Article  CAS  Google Scholar 

  103. Barrero AF, del Moral LFQ, Lara A, Herrador MM (2005) Planta Med 71:67

    Article  CAS  Google Scholar 

  104. Solis C, Becerra J, Flores C, Robledo J, Silva M (2004) J Chil Chem Soc 49:157

    Article  CAS  Google Scholar 

  105. Becerra J, Flores C, Mena J, Aqueveque P, Alarcon J, Bittner M, Hernandez V, Hoeneisen M, Ruiz E, Silva M (2002) Bol Soc Chil Quim 47:151

    CAS  Google Scholar 

  106. Inoue Y, Hada T, Shiraishi A, Hirose K, Hamashima H, Kobayashi S (2005) Antimicrob Agents Chemother 49:1770

    Article  CAS  Google Scholar 

  107. Cotoras M, Garcia C, Lagos C, Folch C, Mendoza L (2001) Bol Soc Chil Quim 46:433

    CAS  Google Scholar 

  108. Cotoras M, Folch C, Mendoza L (2004) J Agric Food Chem 52:2821

    Article  CAS  Google Scholar 

  109. Kim JW, Huh JE, Kyung SH, Kyung KH (2004) Food Sci Biotechnol 13:235

    CAS  Google Scholar 

  110. Kim JW, Kim YS, Kyung KH (2004) J Food Protect 67:499

    CAS  Google Scholar 

  111. Burt S (2004) Int J Food Microbiol 94:223

    Article  CAS  Google Scholar 

  112. Mastelic J, Politeo O, Jerkovic I, Radosevic N (2005) Chem Nat Compd 41:35

    Article  CAS  Google Scholar 

  113. Rivera-Carriles K, Argaiz A, Palou E, Lopez-Malo A (2005) J Food Protect 68:602

    CAS  Google Scholar 

  114. Ultee A, Slump RA, Steging G, Smid EJ (2000) J Food Protect 63:620

    CAS  Google Scholar 

  115. Aggarwal KK, Khanuja SPS, Ahmad A, Kumar TRS, Gupta VK, Kumar S (2002) Flavour Fragrance J 17:59

    Article  CAS  Google Scholar 

  116. Cimanga K, Kambu K, Tona L, Apers S, De Bruyne T, Hermans N, Totte J, Pieters L, Vlietinck AJ (2002) J Ethnopharmacol 79:213

    Article  CAS  Google Scholar 

  117. Cox SD, Mann CM, Markham JL (2001) J Appl Microbiol 91:492

    Article  CAS  Google Scholar 

  118. Carson CF, Mee BJ, Riley TV (2002) Antimicrob Agents Chemother 46:1914

    Article  CAS  Google Scholar 

  119. Cox SD, Mann CM, Markham JL, Bell HC, Gustafson JE, Warmington JR, Wyllie SG (2000) J Appl Microbiol 88:170

    Article  CAS  Google Scholar 

  120. Walsh SE, Maillard J-Y, Russell AD, Catrenich CE, Charbonneau DL, Bartolo RG (2003) J Appl Microbiol 94:240

    Article  CAS  Google Scholar 

  121. Lucini EI (2004) PhD Thesis, Universidad Nacional de Córdoba, Argentina

    Google Scholar 

  122. Holley RA, Patel D (2005) Food Microbiol 22:273

    Article  CAS  Google Scholar 

  123. Rios JL, Recio MC (2005) J Enthopharmacol 100:80

    Article  CAS  Google Scholar 

  124. Jasim SAA, Naji MA (2003) J Appl Microbiol 95:412

    Article  CAS  Google Scholar 

  125. Schnitzler P, Schon K, Reichling J (2001) Pharmazie 56:343

    CAS  Google Scholar 

  126. De Logu A, Loy G, Pellerano ML, Bonsignore L, Schivo ML (2000) Antivir Res 48:177

    Article  Google Scholar 

  127. Valenti D, De Logu A, Loy G, Sinico C, Bonsignore L, Cottiglia F, Garau D, Fadda AM (2001) J Liposome Res 11:73

    Article  CAS  Google Scholar 

  128. Sinico C, De Logu A, Lai F, Valenti D, Manconi M, Loy G, Bonsignore L, Fadda AM (2005) Eur J Pharm Biopharm 59:161

    Article  CAS  Google Scholar 

  129. Garcia CC, Talarico L, Almeida N, Colombres S, Duschatzky C, Damonte EB (2003) Phytother Res 17:1073

    Article  CAS  Google Scholar 

  130. Duschatzky CB, Possetto ML, Talarico LB, García CC, Michis F, Almeida NV, De Lampasona MP, Schuff C, Damonte EB (2005) Antivir Chem Chemother 16:247

    CAS  Google Scholar 

  131. Schuhmacher A, Reichling J, Schnitzler P (2003) Phytomedicine 10:504

    Article  CAS  Google Scholar 

  132. Minami M, Kita M, Nakaya T, Yamamoto T, Kuriyama H, Imanishi J (2003) Microbiol Immunol 47:681

    CAS  Google Scholar 

  133. Marongiu B, Porcedda S, Caredda A, De Gioannis B, Vargiu L, La Colla P (2003) Flavour Fragrance J 18:390

    Article  CAS  Google Scholar 

  134. Burke BE, Baillie JE, Olson RD (2004) Biomed Pharmacother 58:245

    Article  CAS  Google Scholar 

  135. Chiang LC, Ng LT, Cheng PW, Chiang W, Lin CC (2005) Clin Exp Pharmacol P 32:811

    Article  CAS  Google Scholar 

  136. Yang ZC, Wang BC, Yang XS, Wang Q (2005) Colloids Surf B 43:198

    Article  CAS  Google Scholar 

  137. Armaka M, Papanikolaou E, Sivropoulou A, Arsenakis M (1999) Antivir Res 43:79

    Article  CAS  Google Scholar 

  138. Farag RS, Shalaby AS, El-Baroty GA, Ibrahim NA, Ali MA, Hassan EM (2004) Phytother Res 18:30

    Article  CAS  Google Scholar 

  139. Ruberto G, MT Baratta (2000) Food Chem 69:167

    Article  CAS  Google Scholar 

  140. Madsen HL, Bertelsen G (1995) Trends Food Sci Technol 6:271

    Article  CAS  Google Scholar 

  141. Rice-Evans CA, NJ Miller, G, Paganga (1996) Free Radical Biol Med 20:933

    Article  CAS  Google Scholar 

  142. Dragland S, Senoo H, Wake K, Holte K, Blomhoff R (2003) J Nutr 133:1286

    CAS  Google Scholar 

  143. Pietta PG (2000) J Nat Prod 63:1035

    Article  CAS  Google Scholar 

  144. Kwang-Geun L, Takayuki S (2001) Food Chem 74:443

    Article  Google Scholar 

  145. Sanchez-Moreno C (2002) Food Sci Technol Int 8:121

    Article  CAS  Google Scholar 

  146. Choi HS, Song HS, Ukeda H, Sawamura M (2000) J Agric Food Chem 48:4156

    Article  CAS  Google Scholar 

  147. Re R, Pellegrini R, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Free Radical Biol Med 26:1231

    Article  CAS  Google Scholar 

  148. Benzie IFF, JJ Strain (1996) Anal Biochem 239:70

    Article  CAS  Google Scholar 

  149. Dorman HJD, Figueiredo AC, Barroso JG, Deans SG (2000) Flavour Fragrance J 15:12

    Article  CAS  Google Scholar 

  150. Grassmann J, Hippeli S, Vollmann R, Elstner EF (2003) J Agric Food Chem 51:7576

    Article  CAS  Google Scholar 

  151. Koleva TA, van Beek JP, Linssen H, de Groot A, Evstatieva LN (2002) Phytochem Anal 13:8

    Article  CAS  Google Scholar 

  152. Sacchetti G, Maietti S, Muzzoli M, Scaglianti M, Manfredini S, Radice M, Bruni R (2005) Food Chem 91:621

    Article  CAS  Google Scholar 

  153. Burits M, Bucar F (2000) Phytother Res 14:323

    Article  CAS  Google Scholar 

  154. Foti MC, Ingold KU (2003) J Agric Food Chem 51:2758

    Article  CAS  Google Scholar 

  155. El-Ghorab AH, Mansour AF, El-Massry KF (2004) Flavour Fragrance J 19:54

    Article  CAS  Google Scholar 

  156. Ruberto G, Baratta MT, Deans SG, Dorman HJD (2000) Planta Med 66:687

    Article  CAS  Google Scholar 

  157. Singh G, Marimuthu R, De Heluani CS, Catalan C (2005) J Food Sci 70:M141

    Article  CAS  Google Scholar 

  158. Kim HJ, Chen F, Wu CQ, Wang X, Chung HY, Jin ZY (2004) J Agric Food Chem 52:2849

    Article  CAS  Google Scholar 

  159. Mimica-Dukic N, Bozin B, Sokovic M, Simin N (2004) J Agric Food Chem 52:2485

    Article  CAS  Google Scholar 

  160. Menut C, Bessiere JM, Samate D, Djibo AK, Buchbauer G, Schopper B (2000) J Essent Oil Res 12:207

    CAS  Google Scholar 

  161. Teissedre P L, Waterhouse AL (2000) J Agric Food Chem 48:3801

    Article  CAS  Google Scholar 

  162. Juliani HR, Simon JE, Ramboatiana MMR, Behra O, Garvey AS, Raskin I (2004) Acta Hortic 629:77

    Google Scholar 

  163. Lee KG, Shibamoto T (2001) Food Chem 74:443

    Article  CAS  Google Scholar 

  164. Lee KG, Shibamoto T (2001) Food Chem Toxicol 39:1199

    Article  CAS  Google Scholar 

  165. Sacchetti G, Medici A, Maietti S, Radice N, Muzzoli M, Manfredini S, Braccioli E, Bruni R (2004) J Agric Food Chem 52:3486

    Article  CAS  Google Scholar 

  166. Mimica-Dukic N, Bozin B, Sokovic M, Mihajlovic B, Matavulj M (2003) Planta Med 69:413

    Article  CAS  Google Scholar 

  167. Candan F, Unlu M, Tepe B, Daferera D, Polissiou M, Sokmen A, Akpulat HA (2003) J Ethnopharmacol 87:215

    Article  CAS  Google Scholar 

  168. Lee KG, Shibamoto T (2001) J Agric Food Chem 81:1573

    Article  CAS  Google Scholar 

  169. Lado C, Then M, Varga I, Szoke E, Szentmihalyi K (2004) Z Naturforsch C 59:354

    CAS  Google Scholar 

  170. Puertas-Mejia M, Hillebrand S, Stashenko E, Winterhalter P (2002) Flavour Fragrance J 17:380

    Article  CAS  Google Scholar 

  171. Agnaniet H, Makani T, Akagah A, Menut C, Bessiere JM (2005) Flavour Fragrance J 20:34

    Article  CAS  Google Scholar 

  172. Tepe B, Sokmen M, Akpulat HA, Daferera D, Polissiou M, Sokmen A (2005) J Food Eng 66:447

    Article  Google Scholar 

  173. Sokmen A, Gulluce M, Akpulat HA, Daferera D, Tepe B, Polissiou M, Sokmen M, Sahin F (2004) Food Control 15:627

    Article  CAS  Google Scholar 

  174. Sokmen M, Serkedjieva J, Daferera D, Gulluce M, Polissiou M, Tepe B, Akpulat HA, Sahin F, Sokmen A (2004) J Agric Food Chem 52:3309

    Article  CAS  Google Scholar 

  175. Sawa T, Nakao M, Akaike T, Ono K, Maeda H (1999) J Agric Food Chem 47:397

    Article  CAS  Google Scholar 

  176. Karioti A, Hadjipavlou-Litina D, Mensah MLK, Fleischer TC, Skaltsa H (2004) J Agric Food Chem 52:8094

    CAS  Google Scholar 

  177. Yildirim A, Cakir A, Mavi A, Yalcin M, Fauler G, Taskesenligil Y (2004) Flavour Fragrance J 19:367

    Article  CAS  Google Scholar 

  178. Anonymous (1983) Fed Reg 46:5852

    Google Scholar 

  179. Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A, Ghelardini C (2002) Neuroscience Lett 322:146

    Article  Google Scholar 

  180. Galeotti N, Ghelardini C, Di Cesare Mannelli L, Mazzanti G, Baghiroli L, Bartolini A, (2000) Planta Med 66:1

    Google Scholar 

  181. Eccles R (1994) J Pharm Pharmacol 46:18

    Google Scholar 

  182. Sidell N, Verity MA, Nord EP (1990) J Cell Physiol 142:410

    Article  CAS  Google Scholar 

  183. Petersen M, Wagner G, Pierau FK (1989) Naunyn Schmiedebergs Arch Pharmacol 339:184

    Article  CAS  Google Scholar 

  184. Swandulla D, Schafer K, Lux HD (1986) Neurosci Lett 68:23

    Article  CAS  Google Scholar 

  185. Swandulla D, Carbone E, Shafer K, Lux HD (1987) Pflugers Arch 409:52

    Article  CAS  Google Scholar 

  186. Hong CZ, Shellock FG (1991) Am J Phys Med Rehabil 70:29

    Article  CAS  Google Scholar 

  187. White JR (1973) Phys Ther 53:956

    CAS  Google Scholar 

  188. Green BG (1992) Somatosens Mot Res 9:235

    CAS  Google Scholar 

  189. Green BG (1996) J Toxicol Cutan Ocul Toxicol 15:277

    CAS  Google Scholar 

  190. Green BG (1991) Somatosens Mot Res 8:301

    Article  CAS  Google Scholar 

  191. Green BG, McAuliffe BL (2000) Phys Behav 68:631

    Article  CAS  Google Scholar 

  192. Cliff MA, Green BG (1994) Physiol Behav 56:1021

    Article  CAS  Google Scholar 

  193. Cliff MA, Green BG (1996) Physiol Behav 59:487

    Article  CAS  Google Scholar 

  194. Green BG (1986) Physiol Behav 38:833

    Article  CAS  Google Scholar 

  195. Bromm B, Scharein E, Darsow U, Ring J (1995) Neurosci Lett 187:157

    Article  CAS  Google Scholar 

  196. Melton FM, Shelley WB (1950) J Invest Dermatol 15:325

    Article  CAS  Google Scholar 

  197. Yosipovitch G, Szolar C, Hui XY, Maibach H (1996) Arch Dermatol Res 288:245

    CAS  Google Scholar 

  198. Laude EA, Morice AH, Grattan TJ (1994) Pulmonary Pharmacol 7:179

    Article  CAS  Google Scholar 

  199. Morice AH, Marshall AE, Higgins KS, Grattan TJ (1994) Thorax 49:1024

    CAS  Google Scholar 

  200. Barocelli E, Calcina F, Chiavarini M, Impicciatore M, Bruni R, Bianchi A, Ballabeni V (2004) Life Sci 76:213

    Article  CAS  Google Scholar 

  201. Peana AT, De Montis MG, Nieddu E, Spano MT, D’Aquila PS, Pippia P (2004) Eur J Pharmacol 485:165

    Article  CAS  Google Scholar 

  202. Letizia CS, Cocchiara J, Lalko J (2003) Food Chem Toxicol 41:943

    Article  CAS  Google Scholar 

  203. Letizia CS, Cocchiara J, Lalko J (2003) Food Chem Toxical 41:965

    Article  CAS  Google Scholar 

  204. Peana AT, D’Aquila PS, Chessa ML, Moretti MD, Serra G, Pippia P (2003) Eur J Pharmacol 460:37

    Article  CAS  Google Scholar 

  205. Peana AT, D’Aquila PS, Panin F, Serra G, Pippia P, Moretti MD (2002) Phytomedicine 9:721

    Article  CAS  Google Scholar 

  206. Santos FA, Rao VSN (2000) Phyt Res 14:240

    Article  CAS  Google Scholar 

  207. Savelev S, Okello E, Perry NS, Wilkins RM, Perry EK (2003) Pharmacol Biochem Behav 75:661

    Article  CAS  Google Scholar 

  208. Santos FA, Rao VS (2001) Dig Dis Sci 46:331

    Article  CAS  Google Scholar 

  209. Ballabeni V, Tognolini M, Chiavarini M, Impicciatore M, Bruni R, Bianchi A, Barocelli E (2004) Phytomedicine 11:596

    Article  CAS  Google Scholar 

  210. Hajhashemi V, Ghannadi A, Sharif B (2003) J Ethnopharmacol 89:67

    Article  Google Scholar 

  211. Amabeoku GJ, Eagles P, Scott G, Mayeng I, Springfield E (2001) J Ethnopharmacol 75:117

    Article  CAS  Google Scholar 

  212. Shinde UA, Phadke AS, Nair AM, Mungantiwar AA, Dikshit VJ, Saraf MN (1999) J Ethnopharmacol 65:21

    Article  CAS  Google Scholar 

  213. Silva J, Abebe W, Sousa SM, Duarte VG, Machado MIL, Matos FJA (2003) J Ethnopharmacol 89:277

    Article  CAS  Google Scholar 

  214. Gulcin I, Buyukokuroglu ME, Oktay M, Kufrevioglu OI (2003) J Ethnopharmacol 86:51

    Article  Google Scholar 

  215. Abena AA, Diatewa M, Gakosso G, Gbeassor M, Hondi Assah T, Ouamba JM (2003) Fitoterapia 74:231

    Article  CAS  Google Scholar 

  216. Zygadlo JA, Juliani HR (2003) In: Majundar DK, Govil JN, Singh VK (eds) Phytochemistry and Pharmacology II, vol 8. Stadium, Houston, p 273

    Google Scholar 

  217. Meister A, Bernhardt G, Christoffel V, Buschauer A (1999) Planta Med 65:512

    Article  CAS  Google Scholar 

  218. Juliani H R, Wang M, Moharram H, Asante-Dartey J, Acquaye D, Koroch AR, Simon JE (2005) In: Wang M, Shengmin S, Hwang LS, Ho CT (eds) Challenges in Chemistry and Biology of Herbal Research. ACS Symposium Series 925. American Chemical Society, Washington, p 126

    Google Scholar 

  219. Shen J, Niijima A, Tanida M, Horii Y, Maeda K, Nagai K (2005) Neurosci Lett 383:188

    Article  CAS  Google Scholar 

  220. Triadafilopoulos G, Tsang HP (1996) Am J Gastroenterol 91:2224

    CAS  Google Scholar 

  221. Van De Graaff KM, Fox SF (1995) Concepts of human anatomy and physiology. Brown, Dubuque

    Google Scholar 

  222. Tanida M, Niijima A, Shen J, Nakamura T, Nagai K (2005) Brain Res 1058:44

    Article  CAS  Google Scholar 

  223. Shen J, Niijima A, Tanida M, Horii Y, Maeda K, Nagai K (2005) Neurosci Lett 380:289

    Article  CAS  Google Scholar 

  224. Coelho-de-Souza A N, Criddle DN, Leal-Cardoso JH (1998) Phytother Res 12:189

    Article  CAS  Google Scholar 

  225. Hajhashemi V, Sadraei H, Ghannadi AR, Mohseni M (2000) J Ethnopharmacol 71:187

    Article  CAS  Google Scholar 

  226. Sadraei H, Asghari GR, Hajhashemi V, Kolagar A, Ebrahimi M (2001) Phytomedicine 8:370

    Article  CAS  Google Scholar 

  227. Cruz T, Cabo MM, Jiménez J, Zarzuelo A (1990) Fitoterapia 61:247

    CAS  Google Scholar 

  228. Al-Zuhair H, el-Sayeh B, Ameen HA, al-Shoora H (1996) Pharmacol Res 34:79

    Article  CAS  Google Scholar 

  229. Astudillo A, Hong E, Bye R, Navarrete A (2004) Phytother Res 18:102

    Article  CAS  Google Scholar 

  230. Magalhaes PJC, Criddle DN, Tavares RA, Melo EM, Mota TL, Leal-Cardoso JH (1998) Phytother Res 12:172

    Article  CAS  Google Scholar 

  231. Sadraei H, Asghari G, Naddafi A (2003) Phytother Res 17:645

    Article  CAS  Google Scholar 

  232. Lis-Balchin M, Patel J, Hart S (1998) Phytother Res 12:215

    Article  CAS  Google Scholar 

  233. Lis-Balchin M, Hart S (1999) Phytother Res 13:540

    Article  CAS  Google Scholar 

  234. Camara CC, Nascimento NRF, Macedo-Filho CL, Almeida FBS, Fonteles MC (2003) Planta Med 69:1080

    Article  CAS  Google Scholar 

  235. Sadraei H, Asghari G, Naddafi A (2003) Phytother Res 17:645

    Article  CAS  Google Scholar 

  236. Hills JM, Aaronson PI (1991) Gastroenterology 101:55

    CAS  Google Scholar 

  237. Van Den Broucke C, Lemli JA (1982) Planta Med 38:188

    Google Scholar 

  238. Uchiyama T, Chess-Williams R (2004) J Smooth Muscle Res 40:237

    Article  Google Scholar 

  239. Micklefield GH, Greving I, May B (2000) Phytother Res 14:20

    Article  CAS  Google Scholar 

  240. Van de Graaf KM, Fox SM (1995) Fundamentals of Anatomy and Physiology, 4th edn. Brown, Dubuque

    Google Scholar 

  241. Cavanagh HMA, Wilkinson JM (2002) Phytother Res 16:301

    Article  CAS  Google Scholar 

  242. Leiss O, von Bergmann K (1985) Gut 26:32

    CAS  Google Scholar 

  243. Avato P, De Ruvo C, Cellamare S, Carotti A, Mazzoccoli M, Siro-Brigiani G (1998) Pharm Biol 36:335

    CAS  Google Scholar 

  244. Trabace L, Avato P, Mazzoccoli M, Siro-Brigiani G (1994) Phytother Res 8:305

    Article  CAS  Google Scholar 

  245. Lin CC, Yen MH, Lo TS, Lin JM (1998) J Ethnopharmacol 60:9

    Article  CAS  Google Scholar 

  246. Sai-Kato K, Umemura T Takagi A, Hasegawa R, Tanimura A, Kurokawa Y (1995) Food Chem Toxicol 33:877

    Article  CAS  Google Scholar 

  247. Conti M, Malandrino S, Magistretti MJ (1992) Jpn J Pharmacol 60:315

    CAS  Google Scholar 

  248. Morita T, Jinno K, Kawagishi H, Arimoto Y, Suganuma H, Inakuma T, Sugiyama K (2003) J Agric Food Chem 51:1560

    Article  CAS  Google Scholar 

  249. Utrilla MP, Navarro MC, Jimenez J, Montilla MP, Martin A (1995) J Nat Prod 58:1749

    Article  CAS  Google Scholar 

  250. Alam K, Nagi MN, Baday OA, Al-shabanah OA, Al-Rikabi AC, Al-Bekairi AM (1999) Pharmacol Res 40:159

    Article  CAS  Google Scholar 

  251. Ozbek H, Ugras S, Dulger H, Bayram I, Tuncer I, Ozturk G, Ozturk A (2003) Fitoterapia 74:317

    Article  CAS  Google Scholar 

  252. Peana A, Satta M, Moretti MDL, Orecchioni M (1994) Planta Med 60:478–479.

    Article  CAS  Google Scholar 

  253. Fahim FA, Esmat AY, Fadel HM, Hassan KF (1999) Int J Food Sci Nutr 50:413

    Article  CAS  Google Scholar 

  254. Matsunaga T, Hasegawa C, Kawasuji T, Suzuki H, Saito H, Sagioka T, Takahashi R, Tsukamoto H, Morikawa T, Akiyama T (2000) Biol Pharm Bull 23:595

    CAS  Google Scholar 

  255. Perez S, Zavala MA, Vargas R, Perez C, Perez RM, (1998). Phytother Res 12:S45

    Article  Google Scholar 

  256. Hahn WC, Weinberg RA (2002) J Med 347:1593

    CAS  Google Scholar 

  257. Bradlow HL, Sepkovic DW (2002) Ann N Y Acad Sci 963:247

    Article  CAS  Google Scholar 

  258. Darmon N, Khlar M (2001) Public Health Nutr 4:163

    CAS  Google Scholar 

  259. Greenwald P, Clifford CK, Milner JA (2001) Eur J Cancer 37:948

    Article  CAS  Google Scholar 

  260. da Rocha AB, Lopes RM, Schwartsmann G (2001) Curr Opin Pharmacol 1:364

    Article  Google Scholar 

  261. Trichopoulou A, Lagiou P, Keper H, Trichopoulo D (2000) Cancer Epidemol Biomarkers Prev 9:869

    CAS  Google Scholar 

  262. Sugimura T (2000) Carcinogenesis 21:387

    Article  CAS  Google Scholar 

  263. Crowell PL (1999) J Nutr 129:775S

    CAS  Google Scholar 

  264. Crosignani P, Russo A, Tagliabue G, Berrino F (1996) Int J Cancer 65:309

    Article  Google Scholar 

  265. Tatman D, Mo H (2002) Cancer Lett 175:129

    Article  CAS  Google Scholar 

  266. Elson CE (1995) J Nutr 125:1666s

    CAS  Google Scholar 

  267. Wattenberg LW (1983) Cancer Res 43:2488

    Google Scholar 

  268. Wattenberg LW (1985) Cancer Res 45:1

    Article  CAS  Google Scholar 

  269. Hartman PE, Shankel DM (1990) Environ Mol Mutagen 15:145

    Article  CAS  Google Scholar 

  270. Block KI, Gyllenhaal C, Mead MN (2004) Int Cancer Ther 3:128

    Article  CAS  Google Scholar 

  271. Mo H, Elson CE (2004) Exp Biol Med 229:567

    CAS  Google Scholar 

  272. Dorai T, Aggarwal BB (2004) Cancer Lett 215:129

    Article  CAS  Google Scholar 

  273. Maddocks W (2002) Int J Aromat 12: 30

    Article  Google Scholar 

  274. Guba R (2000) Toxicity myths essential oils and their carcinogenic potential. In: Essential Oils and Cancer. Proceedings of the 4th Wholistic Aromatherapy Conference, San Francisco

    Google Scholar 

  275. Elson CE, Peffley DM, Hentosh P, Mo H (1999) Proc Soc Exp Biol Med 221:294

    Article  CAS  Google Scholar 

  276. Elson CE, Yu SG (1994) J Nutr 124:607

    CAS  Google Scholar 

  277. Matura M, Goossens A, Bordalo O, Garcia-Bravo B, Magnusson K, Wrangsjo K, Karlberg AT (2002) J Am Acad Dermatol 47:709

    Article  Google Scholar 

  278. Flavor and Extract Manufacturers’ Association (1991) D-Limonene monographa. Flavor and Extract Manufacturers’ Association, Washington, p 1

    Google Scholar 

  279. Phillips LR, Malspeis L, Supko JG (1995) Drug Metab Dispos 23:676

    CAS  Google Scholar 

  280. Kaji I, Tatsuta M, Iishi H, Baba M, Inoue A, Kasugai H (2001) Int J Cancer 93:441

    Article  CAS  Google Scholar 

  281. Maltzman TH, Hurt LM, Elson CE, Tanner MA, Gould MN (1989) Carcinogenesis 10:781

    Article  CAS  Google Scholar 

  282. Lu XG, Zhan LB, Feng BA, Qu MY, Yu LH, Xie JH (2004) World J Gastroenterol 10:2140

    CAS  Google Scholar 

  283. Koo HN, Hong SH, Kim CY, Ahn JW, Lee YG, Kim JJ, Lyu YS, Kim HM (2002) Pharm Res 45:469

    Article  CAS  Google Scholar 

  284. Bardon S, Picard K, Martel P (1998) Nutr Cancer 32:1

    Article  CAS  Google Scholar 

  285. Izumi S, Takashima O, Hirata T (1999) Biochem Biophys Comm 259:519

    Article  CAS  Google Scholar 

  286. Hardcastle IR, Rowlands MG, Barber AM, Grimshaw RM, Mohan MK, Nutley BP, Jarman M (1999) Biochem Pharmacol 57:801

    Article  CAS  Google Scholar 

  287. Kawata S, Hagase T, Yamasaki E, Ishiguro H, Matsuzawa Y (1994) J Cancer 69:1015

    CAS  Google Scholar 

  288. Crowell PL (1997) Breast Cancer Res Treat 46:191

    Article  CAS  Google Scholar 

  289. Gelb MH, Tamanoi F, Yokoyama K, Ghomashci F, Esson K, Gould MM (1995) Cancer Lett 91:168.

    Article  Google Scholar 

  290. Crowell PL, Elegbede JA, Elson CE, Lin S, Baltey HH, Vedejs E, Gould MN (1994) Cancer Chemother Pharmacol 35:31

    CAS  Google Scholar 

  291. Crowell PL, Chang RR, Ren Z, Elson CE, Gould MN (1991) J Biol Chem 266:17679

    CAS  Google Scholar 

  292. Crowell PL, Kennan WS, Haag JD, Ahmad S, Vedejs E, Gould MN (1992) Carcinogenesis 13:1261

    Article  CAS  Google Scholar 

  293. Crowell PL, Lin S, Vedejes E, Gould MN (1992) Cancer Chemother Pharmacol 31:205

    Article  CAS  Google Scholar 

  294. Schulz S, Buhiing F, Ansorge S (1994) Eur J Immunol 24:301

    CAS  Google Scholar 

  295. Miquel K, Pradines A, Terce F, Selmi S, Favre G (1998) J Biol Chem 273:26179

    Article  CAS  Google Scholar 

  296. Gana-Weisz M, Halaschek Wiener J, Jansen B, Elad G, Haklai R, Kloog Y (2002) Clin Cancer Res 8:555

    CAS  Google Scholar 

  297. Egozi Y, Weisz B, Gana Weisz M, Ben Baruch G, Kloog Y (1999) Int J Cancer 80:911

    Article  CAS  Google Scholar 

  298. Haklai R, Weisz MG, Elad G, Paz A, Marciano D, Egozi Y, Ben-Baruch G, Kloog Y (1998) Biochemistry 37:1306

    Article  CAS  Google Scholar 

  299. Marciano D, Ben-Baruch G, Marom M, Egozi Y, Haklai R, Kloog Y (1995) J Med Chem 38:1267

    Article  CAS  Google Scholar 

  300. Ura H, Obara T, Shudo R, Itho A, Tanno S, Fujii T, Nishino N, Khogo Y (1998) Mol Carcinog 21:93

    Article  CAS  Google Scholar 

  301. Haag JD, Gould (1994) Cancer Chemother Pharmacol 34:477

    CAS  Google Scholar 

  302. Steams V, Coop A, Singh B, Gallagher A, Yamauchi H, Lieberman R, Pennanen M, Trock B, Hayes DF, Ellis MJ (2004) Clin Cancer Res 10:7583

    Article  Google Scholar 

  303. Chow HH, Salazar D, Hakin IA (2002) Cancer Epidemiol Biomarkers Prev 11:1472

    CAS  Google Scholar 

  304. Vigushin DM, Poon GK, Boddy A, English J, Halbert GW, Pagonis C, Jarman M, Coombes RC (1998) Cancer Chemother Pharmacol 42:11

    Article  Google Scholar 

  305. Azzoli CG, Miller VA, Nig KK, Krug LM, Spriggs DR, Tong WP, Riedel ER, Kris MG (2003) Cancer Chemother Pharmacol 51:493

    CAS  Google Scholar 

  306. Liu G, Oettel K, Bailey H, Van Ummersen L, Tutsch K, Staab MJ, Horvath D, Alberti D, Arzoomanian R, Rezazadeh H, McGovern J, Robinson E, De Mets D, Wilding G (2003) Invest New Drugs 21:367

    Article  CAS  Google Scholar 

  307. Bailey HH, Levy D, Harris LS, Schink JC, Foss F, Beatty P, Wadler S (2002) Gynecol Oncol 85:464

    Article  CAS  Google Scholar 

  308. Meadows SM, Mulkerin D, Berlin J, Bailey H, Kolesar J, Warren D, Thomas JP (2002) Int J Gastrointest Cancer 32:125

    Article  CAS  Google Scholar 

  309. Murren JR, Pizzorno G, DiStasio SA, McKeon A, Peccerillo K, Gollerkari A, McMurray W, Burtness BA, Rutherford T, Li X, Ho PT, Sartorelli A (2002) Cancer Biol Ther 1:130

    CAS  Google Scholar 

  310. Hudes GR, Szarka CE, Adams A, Ranganathan S, McCauley RA, Weiner LM, Langer CJ, Litwin S, Yeslow G, Halberr T, Qian M, Gallo JM (2000) Clin Cancer Res 6:307

    Google Scholar 

  311. Ripple GH, Gould MN, Arzoomanian RZ, Alberti D, Feierabend C, Pomplun M, Simon K, Binger K, Tutsch KD, Pomplun M, Wahamaki A, Marnocha R, Wilding G, Bailey HH (2000) Clin Cancer Res 6:390

    CAS  Google Scholar 

  312. Elegbede JA, Flores R, Wang RC (2003) Life Sci 73:2831

    Article  CAS  Google Scholar 

  313. Clark SS, Zhong L, Filiault D, Perman S, Ren Z, Gould M, Yang X (2003) Clin Cancer Res 9:4494

    CAS  Google Scholar 

  314. Sahin MB, Perman SM, Jenkins G, Clark SS (1999) Leukemia 13:1581

    Article  CAS  Google Scholar 

  315. Stayrook KR, McKinzie JH, Burke YD, Burke YA, Crowell PL (1997) Carcinogenesis 18:1655

    Article  CAS  Google Scholar 

  316. Bardon S, Foussard V, Fournel S, Loubat A (2002) Cancer Lett 181:187

    Article  CAS  Google Scholar 

  317. Shi WG, Gould MN (2002) Carcinogenesis 23:131

    Article  CAS  Google Scholar 

  318. Ariazi EA, Satomi Y, Ellis MJ, Haag JD, Shi W, Sattler CA, Gould MN (1999) Cancer Res 59:1917

    CAS  Google Scholar 

  319. Elegbede JA, Flores R, Wang RC (2003) Life Sci 73:2831

    Article  CAS  Google Scholar 

  320. Ferri N, Arnaboldi L, Orlandi A, Yokoyama K, Gree R, Granata A, Hachem A, Paoletti R, Gelb MH, Corsini A (2001) Biochem Pharmacol 62:1637

    Article  CAS  Google Scholar 

  321. Clark SS, Perman SM, Sahin MB, Jenkins GJ, Elegbede JA (2002) Leukemia 16:213

    Article  CAS  Google Scholar 

  322. Reddy BS, Wang CX, Samaha H, Lubert R, Steele VE, Kelloff GJ, Rao CV (1997) Cancer Res 57:420

    CAS  Google Scholar 

  323. Mills JJ, Chari RS, Boyer IJ, Gould MN, Jirtle RL (1995) Cancer Res 55:979

    CAS  Google Scholar 

  324. Jirte RL, Haag JD, Ariazi EA, Gould MN (1993) Cancer Res 53:3849

    Google Scholar 

  325. Lluria-Prevatt M, Morreale J, Gregus J, Alberts DS, Kaper F, Giaccia A, Powell MB (2002) Cancer Epidemiol Biomarkers Prev 11:573

    CAS  Google Scholar 

  326. Stayrook KR, McKinzie JH, Barbhaiya LH, Crowell PL (1998) Anticancer Res 18:823

    CAS  Google Scholar 

  327. Ren Z, Elson CE, Gould MN (1997) Biochem Pharmacol 54:113

    Article  CAS  Google Scholar 

  328. Cates CA, Michael RL, Stayrook KR, Harvey KA, Burke YD, Randall SK, Crowll PL, Crowell DN (1996) Cancer Lett 110:49

    Article  CAS  Google Scholar 

  329. Berchtold CM, Chen KS, Miyamoto S, Gould MN (2005) Cancer Res 65:8558

    Article  CAS  Google Scholar 

  330. Zheng GQ, Kenney PM, Lam LKT (1992) J Nat Prod 55:999

    Article  CAS  Google Scholar 

  331. Miyazawa M, Hisama M (2001) J Agric Food Chem 49:4019

    Article  CAS  Google Scholar 

  332. Rompelberg CJM, Verhagen H, van Bladeren PJ (1993) Food Chem Toxicol 31:637

    Article  CAS  Google Scholar 

  333. Rompelberg CJM, Stenhuis WH, de Vogel N, van Osenbruggen WA, Schouten A, Verhagen H (1995) Mutat Res 346:69

    Article  CAS  Google Scholar 

  334. Rompelberg CJM, Evertz SJCJ, Bruijintjes-Rozier GCDM, van den Heuvel PD, Verhagen H (1996) Food Chem Toxicol 34:33

    Article  CAS  Google Scholar 

  335. Rompelberg CJM, Steenwinkel MJ, van Asten JG, van Delft JH, Baan RA, Verhagen H (1996) Mutat Res 369:87

    Article  CAS  Google Scholar 

  336. Rompelberg CJM, Vogels JT, de Vogel N, Bruijntjes-Rozier GC, Stenhuis WH, Bogaards JJ, Verhagen H (1996) Human Exp Toxicol 15:129

    Article  CAS  Google Scholar 

  337. Yokota H, Hashimoto H, Motoya M, Yuasa A (1988) Biochem Pharmacol 37:799

    Article  CAS  Google Scholar 

  338. Newbeerne P, Smith RL, Doull J, Goodman JI, Munro IC, Portoghese PS, Wagner BM, Weil CS, Woods LA, Adams TB, Lucas CD, Ford RA (1999) Food Chem Toxicol 37:787

    Google Scholar 

  339. Fujisawa S, Atsumi T, Kadoma Y, Sakagami H (2002) Toxicology 177:39

    Article  CAS  Google Scholar 

  340. Nagababu E, Lakshmaiah N (1992) Biochem Pharmacol 43:2393

    Article  CAS  Google Scholar 

  341. Udilova N, Jurek D, Marian B, Gille L, Schulte Hermann R, Nohl H (2003) Food Chem Tox 41:1481

    Article  CAS  Google Scholar 

  342. Gonzalez MJ (1992) Med Hypotheses 38:106

    Article  CAS  Google Scholar 

  343. Yoo CB, Han KT, Cho KS, Ha J, Park HJ, Nam JH, Kil UH, Lee KT (2005) Cancer Lett 225:41

    Article  CAS  Google Scholar 

  344. Francis AR, Shetty TK, Bhattacharya RK (1989) Cancer Lett 45:177

    Article  CAS  Google Scholar 

  345. Abraham SK (2001) Food Chem Toxicol 39:493

    Article  CAS  Google Scholar 

  346. Wattenberg LW, Spamins VL, Barany G (1989) Cancer Res 48:2688

    Google Scholar 

  347. Raphael TJ, Kuttan G (2003) J Exp Clin Cancer Res 22:419

    CAS  Google Scholar 

  348. Shoff SM, Grummer M, Yatvin MB, Elson CE (1991) Cancer Res 51:37

    CAS  Google Scholar 

  349. Yu SG, Hildebrandt LA, Elson CE (1995) J Nutr 125:2763

    CAS  Google Scholar 

  350. Carnesecchi S, Schneider Y, Ceraline J, Duranton B, Gosse F, Seiler N, Raul F (2001) J Pharmacol Exp Ther 298:197

    CAS  Google Scholar 

  351. Carnesecchi S, Bradaia A, Fischer B, Coelho D, Scholler-Guinard M, Gosse F, Raul F (2002) J Pharmacol Exp Ther 303:711

    Article  CAS  Google Scholar 

  352. Carnesecchi S, Goncalves RB, Bradaia A, Zeisel M., Gosse F, Poupon MF, Raul F (2004) Cancer Lett 215:53

    Article  CAS  Google Scholar 

  353. Duncan RE, Lau D, ElSohemy A, Archer MC (2004) Biochem Pharmacol 68:1739

    Article  CAS  Google Scholar 

  354. Mc Anally JA, Jung M, Mo H (2003) Cancer Lett 202:181

    Article  CAS  Google Scholar 

  355. Clegg RJ, Middieton B, Bell D, White DA (1982) J Biol Chem 257:2294

    CAS  Google Scholar 

  356. Budavari S (1996) The Merk Index, 12th edn. Merck Research Laboratories Division of Merck & Co, Whitehouse Station, p 208

    Google Scholar 

  357. Cavalieri E, Mariotto S, Fabrizi C, Carcereri de Prati A, Gottardo R, Leone S, Berra LV, Lauro GM, Ciampa AR, Suzuki H (2004) Res Commun 315:589

    CAS  Google Scholar 

  358. Hernandez Ceruelos A, Madrigal Bujaidar E, de la Cruz C (2002) Toxicol Lett 135:103

    Article  CAS  Google Scholar 

  359. Surth YJ (2003) Nat Rev Cancer 3:768

    Article  CAS  Google Scholar 

  360. Bharti AC, Aggarwal BB (2002) Biochem Pharmacol 64:883

    Article  CAS  Google Scholar 

  361. Kim JH, Lee HJ, Kim GS, Choi DH, Lee SS, Kang JK, Chae C, Paik NW, Cho MH (2004) Cancer Lett 213:139

    Article  CAS  Google Scholar 

  362. Zeytinoglu H, Incesu Z, Baser KHC (2003) Phytomedicine 10:292

    Article  CAS  Google Scholar 

  363. Russin WA, Hoesly JD, Elson CE, Tanner MA, Gould MN (1989) Carcinogenesis 10:2161

    Article  CAS  Google Scholar 

  364. Ka H, Park HJ, Jung HJ, Choi JW, Cho KS, Ha J, Lee KT (2003) Cancer Lett 196:143

    Article  CAS  Google Scholar 

  365. Wright MM, Henneberry AL, Lagace TA, Ridgway ND, McMaster CR (2001) J Biol Chem 276:25254

    Article  CAS  Google Scholar 

  366. Imai T, Yasuhara K, Tamura T, Takizawa T, Ueda, Hirose M (2002) Cancer Lett 175:9

    Article  CAS  Google Scholar 

  367. Idaomar M, El Hamss R, Bakkali F, Mezzoug N, Zhiri A, Baudoux D, Munoz Serrano A, Liemans V, Alonso-Moraga A (2002) Mutat Res 512:61

    Google Scholar 

  368. Letizia CS, Cocchiara J, Lalko J, Api AM (2003) Food Chem Toxicol 41:43

    Google Scholar 

  369. Sasaki YF, Imanishi H, Phta T, Shirasu Y (1989) Mutat Res 226:103

    Article  CAS  Google Scholar 

  370. Bickers D, Greim H, Hanifin JH, Rogers AE, Saurat JH, Sipes LG, Smith RL, Tagami H (2003) Food Chem Toxicol 41:919

    Article  CAS  Google Scholar 

  371. Van Duuren BL, Blazej T, Goldschmidt BM, Katz C, Melchionne S, Sivak A (1971) J Natl Cancer Inst 46:1039

    Google Scholar 

  372. De Vincenzi M, Silano M, Maialetti F, Scazzocchio B (2000) Fitoterapia 71:725

    Article  Google Scholar 

  373. Burkey JL, Sauer JM, McQueen CA, Sipes IG (2000) Mutat Res 453:25

    CAS  Google Scholar 

  374. Abdo KM, Cunningham ML, Snell ML, Herbert RA, Travlos GS, Eldridge SR, Bucher JR (2001) Food Chem Toxicol 39:303

    Article  CAS  Google Scholar 

  375. Smith RL, Adams TB, Doull J, Feron VJ, Goodman JI, Marnett LJ, Portoghese PS, Waddell WJ, Wagner BM, Rogers AE, Caldwell J, Sipes IG (2004) Food Chem Toxicol 40:851

    Article  Google Scholar 

  376. Burguiere L, Marion-Poll F, Cork A (2001) J Insect Physiol 47:509

    Article  CAS  Google Scholar 

  377. Borg-Karlson AK, Unelius CR, Valterova I and Nilsson LA (1996) Phytochemistry 41:1477

    Article  CAS  Google Scholar 

  378. Bengtsson M, Backman AC, Liblikas I, Ramirez MI, Borg-Karlson AK, Ansebo L, Anderson P, Lofqvist J, Witzgall P (2001) J Agric Food Chem 49:3736

    Article  CAS  Google Scholar 

  379. Pureswaran DS, Gries R, Borden JH (2004) Chemoecology 14:59

    Article  CAS  Google Scholar 

  380. Allison JD, Borden JH, Seybold SJ (2004) Chemoecology 14:123

    Article  CAS  Google Scholar 

  381. Gadi V, Reddy P, Guerrero A (2004) Trends Plant Sci 9:253

    Article  CAS  Google Scholar 

  382. Bichao H, Borg-Karlson AK, Araujo J, Mustaparta H (2003) J Comp Physiol A 189:203

    CAS  Google Scholar 

  383. Stranden M, Rostelien T, Liblikas I, Almaas TJ, Borg-Karlson AK, Mustaparta H (2003) Chemoecology 13:143

    Article  CAS  Google Scholar 

  384. Rostelien T, Borg-Karlson AK, Faldt J, Jacobsson U, Mustaparta H (2000) Chem Senses 25:141

    Article  CAS  Google Scholar 

  385. Mozuraitis R, Stranden M, Ramirez MI, Borg-Karlson AK, Mustaparta H (2002) Chem Senses 27:505

    Article  CAS  Google Scholar 

  386. Reisenman CE, Christensen TA, Francke W, Hildebrand JG (2004) J Neurosci 24:2602

    Article  CAS  Google Scholar 

  387. Allison JD, Morewood WD, Borden JH, Hein KE, Wilson IM (2003) Environ Entomol 32:23

    Article  CAS  Google Scholar 

  388. Mühlbauer RC, Lozano A, Palacio S, Reinli A, Felix R (2003) Bone 32:372

    Article  CAS  Google Scholar 

  389. Yamaguchi K, Shinohara C, Kojima S, Sodeoka M, Tsuji T (1999) Biosci Biotechnol Biochem 63:731

    Article  CAS  Google Scholar 

  390. Perry NSL, Bollen C, Perry EK, Ballard C (2003) Pharmacol Biochem Behav 75:651

    Article  CAS  Google Scholar 

  391. Wei Chen S, Min L, Jing Li W, Xi Kong W, Fang Li J, Jing Zhang Y (2004) Pharmacol Biochem Behav 79:377

    Article  CAS  Google Scholar 

  392. Broughan C (2002) Int J Aromather 12:92

    Article  Google Scholar 

  393. Svoboda KP, Karavia AN, McFarlane V (2002) Int J Aromather 12:67

    Google Scholar 

  394. Alexander M (2002) Int J Aromather 12:49

    Article  Google Scholar 

  395. Standen MD, Myers SP (2004) Int J Aromather 14:150

    Article  CAS  Google Scholar 

  396. Vale TG, Matos FJA, de Lima TCM, Viana GSB (1999) J Ethnopharmacol 167:127

    Article  Google Scholar 

  397. Aloisi AM, Ceccarelli I, Masi F, Scaramuzzino A (2002) Behav Brain Res 136:127

    Article  CAS  Google Scholar 

  398. Ceccarelli I, Lariviere WR, Fiorenzani P, Sacerdote P, Aloisi AM (2004) Brain Res 1001:78

    Article  CAS  Google Scholar 

  399. Spinella M (2001) Epilepsy Behav 2:524

    Article  Google Scholar 

  400. Orafidiya LO, Agbani EO, Oyedele AO, Babalola OO, Onayemi O, Aiyedun FF (2004) Int J Aromather 14:15

    Article  CAS  Google Scholar 

  401. Rosa MSS, Mendonca Filho RR, Bizzo HR, Rodrigues IA, Soares RMA, Souto Padron T, Alviano CS, Lopes AHCS (2003) Antimicrob Agents Chemother 1895

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. New Use Agriculture and Natural Plant Products Program, Cook College, Rutgers University, 59 Dudley Rd, New Brunswick, NJ, 08901, USA

    Adolfina R. Koroch & H. Rodolfo Juliani

  2. Instituto Multidisciplinario de Biologia Vegetal (IMBIV-CONICET), National University of Córdoba, Argentina

    Julio A. Zygadlo

Authors
  1. Adolfina R. Koroch
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Rodolfo Juliani
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Julio A. Zygadlo
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. FB Chemie, Institut für Lebensmittelchemie, Universität Hannover, Wunstorferstraße 14, 30453, Hannover, Germany

    Ralf Günter Berger

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Koroch, A.R., Rodolfo Juliani, H., Zygadlo, J.A. (2007). Bioactivity of Essential Oils and Their Components. In: Berger, R.G. (eds) Flavours and Fragrances. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49339-6_5

Download citation

Publish with us

Policies and ethics

Search

Navigation