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Multiple Nonhistonel Protein-DNA Complexes in Chromatin Regulate the Cell- and Stage-Specific Activity of an Eukaryotic Gene

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Structure and Function of Eukaryotic Chromosomes

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 14))

Abstract

The general mechanisms underlying cell differentiation are still widely unknown. At present, we are forced to reduce the complexity of problems to more basic questions. In a first approximation, cell differentiation must be considered to be the result of differential expression of the same genomic information present in all cell types of an organism. In regards to this, we have asked the question: “What mechanism during cell differentiation prepares an eukaryotic gene so that it is activated only in a specific cell type and only at the right period of time?”

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Authors and Affiliations

  1. Zentrum für Molekulare Biologie, Universität Heidelberg (ZMBH), Im Neuenheimer Feld 282, 6900, Heidelberg 1, Germany

    M. Theisen

Authors
  1. A. E. Sippel
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  2. U. Borgmeyer
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  3. A. W. Püschel
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  4. R. A. W. Rupp
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  5. A. Stief
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  6. U. Strech-Jurk
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  7. M. Theisen
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Editors and Affiliations

  1. Department of Genetics, Faculty of Sciences, University of Nijmegen, 6525 ED, Toernooiveld, Nijmegen, The Netherlands

    Wolfgang Hennig

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© 1987 Springer-Verlag Berlin Heidelberg

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Sippel, A.E. et al. (1987). Multiple Nonhistonel Protein-DNA Complexes in Chromatin Regulate the Cell- and Stage-Specific Activity of an Eukaryotic Gene. In: Hennig, W. (eds) Structure and Function of Eukaryotic Chromosomes. Results and Problems in Cell Differentiation, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47783-9_16

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  • DOI: https://doi.org/10.1007/978-3-540-47783-9_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-22438-0

  • Online ISBN: 978-3-540-47783-9

  • eBook Packages: Springer Book Archive

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