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Structure, Evolution and Functional Roles of Plant Glutathione Transferases

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Glutathione in Plant Growth, Development, and Stress Tolerance

Abstract

Plant cytosolic glutathione transferases (EC 2.5.1.18, GSTs) are essential enzymes involved in multiple and diverse functions which are crucial to xenobiotic detoxification, hormone signalling, redox homeostasis, plant metabolism, growth regulation and adaptation to abiotic and biotic stresses. GSTs are capable of catalysing the conjugation of reduced glutathione (γ-L-Glu-L-Cys-Gly; GSH), via the sulphydryl group, to electrophilic centres on a vast number of molecules, both endogenous and xenobiotic, including herbicides, leading to their detoxification. Recent progress of plant proteomics, genomics and transcriptomics projects has allowed the identification, classification and evolutionary analysis of a large number of GST isoenzymes and has provided new knowledge and insights into their in planta function and catalytic role. This chapter focuses on plant GSTs and attempts to give an overview of their evolution, catalytic function and structural biology.

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Acknowledgements

FSA and NEL extend their appreciation to the International Scientific Partnership Program (ISPP) at King Saud University for funding this research work through ISPP# 0071.

Author information

Authors and Affiliations

  1. Laboratory of Enzyme Technology, Department of Biotechnology, School of Food, Biotechnology and Development, Agricultural University of Athens, 75 Iera Odos Street, GR-11855, Athens, Greece

    Evangelia Chronopoulou, Fotini Pouliou, Fereniki Perperopoulou, Nikolaos Georgakis, Elisavet Ioannou & Nikolaos E. Labrou

  2. Department of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia

    Farid S. Ataya

  3. Laboratory of Genetics and Plant Breeding, School of Agriculture, Forestry and Natural Environment Aristotle University of Thessaloniki, P.O. Box 261, Thessaloniki, GR-54124, Greece

    Irini Nianiou-Obeidat

  4. Institute of Applied Biosciences, CERTH, 6th km Charilaou-Thermis Road, P.O. Box 361, Thermi, GR-57001, Thessaloniki, Greece

    Panagiotis Madesis

Authors
  1. Evangelia Chronopoulou
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  2. Farid S. Ataya
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  3. Fotini Pouliou
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  4. Fereniki Perperopoulou
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  5. Nikolaos Georgakis
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  6. Irini Nianiou-Obeidat
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  7. Panagiotis Madesis
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  8. Elisavet Ioannou
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  9. Nikolaos E. Labrou
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Corresponding author

Correspondence to Nikolaos E. Labrou .

Editor information

Editors and Affiliations

  1. Department of Genetics and Plant Breeding, Bangladesh Agricultural University, Mymensingh, Bangladesh

    Mohammad Anwar Hossain

  2. Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh

    Mohammad Golam Mostofa

  3. Department of Plant Breeding, CEBAS-CSIC, Murcia, Murcia, Spain

    Pedro Diaz-Vivancos

  4. Department of Botany, University of Otago, Dunedin, Otago, New Zealand

    David J Burritt

  5. Department of Applied Biological Science, Kagawa University, Kagawa, Japan

    Masayuki Fujita

  6. RIKEN Center for Sustainable Resource Science, Signaling Pathway Research Unit, Yokohama, Japan

    Lam-Son Phan Tran

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Chronopoulou, E. et al. (2017). Structure, Evolution and Functional Roles of Plant Glutathione Transferases. In: Hossain, M., Mostofa, M., Diaz-Vivancos, P., Burritt, D., Fujita, M., Tran, LS. (eds) Glutathione in Plant Growth, Development, and Stress Tolerance. Springer, Cham. https://doi.org/10.1007/978-3-319-66682-2_9

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