Overview
- Timely State-of-the-science on CRISPR and gene editing, an exciting and controversial frontier in regenerative medicine
- Contributed by top experts in this rapidly-evolving field
- One of the first books to connect genetically modified foods to this area
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1016)
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About this book
This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.
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Keywords
Table of contents (9 chapters)
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Front Matter
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Introduction to the CRISPR Revolution
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Front Matter
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CRISPR in Model Systems
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Front Matter
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Editors and Affiliations
About the editor
For years, Stephen Tsang has been culturing embryonic stem (ES) cells and created the first mouse model for a recessive form of retinitis pigmentosa by applying homologous recombination to ES cell technology. Two elements define his laboratory. First, by leveraging his genetics clinical practice, in which over 1000 retinal patients are cared for, he brings an array of clinical resources to his research, including stem cells and live imaging data. Second, he and his students are recognized authorities in a broad array of state-of-the-art technologies. Most recently, he was invited as a Moderator for the Gene Editing/Rewriting the Genome session during the 65th American Society of Human Genetics Annual Meeting.
Bibliographic Information
Book Title: Precision Medicine, CRISPR, and Genome Engineering
Book Subtitle: Moving from Association to Biology and Therapeutics
Editors: Stephen H. Tsang
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-63904-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-63903-1Published: 21 November 2017
Softcover ISBN: 978-3-319-87667-2Published: 05 September 2018
eBook ISBN: 978-3-319-63904-8Published: 11 November 2017
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: IX, 178
Number of Illustrations: 4 b/w illustrations, 15 illustrations in colour
Topics: Regenerative Medicine/Tissue Engineering, Stem Cells, Ophthalmology, Human Genetics, Agriculture