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Mammalian Cell-Based Biosensors

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Handbook of Cell Biosensors

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Abstract

The chapter deals with the start-of the art of mammalian cell-based biosensors given the main emphasize to optical, electrochemical, impedimetric (ECIS) and quartz microbalance (QMB) sensing. Because fluorescence sensing is the most common detection mode, the corresponding development of reporter gene constructs is dealt in detail. In three-dimensional cell-constructs the scaffold is very important for the structure of the cells, the survival time, the interaction with the neighbor cell or with other kinds of cells therefore a small chapter will deal with the material basis and special properties various scaffolds have (in dependence upon the cell line used).

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Authors and Affiliations

  1. Ernst-Abbe-University Jena, Jena, Germany

    Karl-Heinz Feller

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  1. Karl-Heinz Feller
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Correspondence to Karl-Heinz Feller .

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Editors and Affiliations

  1. UMR CNRS 6144 GEPEA, Université de Nantes, La Roche sur Yon, France

    Gerald Thouand

Section Editor information

  1. Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

    Shimshon Belkin

  2. Faculty of Medicine, Imperial College, London, UK

    Paul Freemont

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Feller, KH. (2021). Mammalian Cell-Based Biosensors. In: Thouand, G. (eds) Handbook of Cell Biosensors. Springer, Cham. https://doi.org/10.1007/978-3-319-47405-2_193-2

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  • DOI: https://doi.org/10.1007/978-3-319-47405-2_193-2

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  • Print ISBN: 978-3-319-47405-2

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Chapter history

  1. Latest

    Mammalian Cell-Based Biosensors
    Published:
    12 June 2021

    DOI: https://doi.org/10.1007/978-3-319-47405-2_193-2

  2. Original

    Mammalian Cell-Based Biosensors
    Published:
    08 May 2021

    DOI: https://doi.org/10.1007/978-3-319-47405-2_193-1

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