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Biodegradable Polymeric Materials

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Regenerative Medicine - from Protocol to Patient

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Abstract

The ability of polymers to be degraded in physiological environments makes them interesting candidates for various medical applications. Degradation and metabolisation or excretion of polymeric implants can avoid a second surgery for the removal of an implant. They follow a distinct pathway for degradation, depending on their structure. Biodegradable materials can serve as a temporary substitute of the extracellular matrix or as matrix in controlled drug release systems, which both can be utilized in Regenerative Therapies.

This chapter gives an overview about polymeric materials established in clinical use such as polyesters, polyurethanes, polyanhydrides, or carbohydrates. It describes further their synthesis and exemplary applications such as surgical sutures. Finally the importance of a continuing development of novel materials for future applications is pointed out, since the number of potential applications in the medical field is expanding rapidly.

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Acknowledgements

We would like to thank the Deutsche Forschungsgemeinschaft (DFG, SFB 760) and the Bundesministerium für Bildung und Forschung (BMBF, FKZ1315848A) for supporting the interdisciplinary research in the field of tissue regeneration.

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  1. Institute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, Kantstr. 55, 14513, Teltow, Germany

    Michael Schroeter & Andreas Lendlein

  2. Julius Wolff Institute, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany

    Britt Wildemann

  3. Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Teltow and Berlin, Germany

    Britt Wildemann & Andreas Lendlein

Authors
  1. Michael Schroeter
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  2. Britt Wildemann
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  3. Andreas Lendlein
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Correspondence to Andreas Lendlein .

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Editors and Affiliations

  1. Department of Cardiac Surgery, University of Rostock, Rostock, Mecklenburg-Vorpomm., Germany

    Gustav Steinhoff

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© 2016 Springer International Publishing Switzerland

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Schroeter, M., Wildemann, B., Lendlein, A. (2016). Biodegradable Polymeric Materials. In: Steinhoff, G. (eds) Regenerative Medicine - from Protocol to Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-28274-9_4

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