Overview
- Historical reminiscence of Professor Sir Anthony Epstein on the discovery of EBV 50 years ago
- 32 comprehensive chapters on EBV virology, tumorigenesis and immune control
- Newest insights on EBV strain variation, the recombinant EBV system and in vivo models of infection
- Comprehensive account of EBV associated diseases, including autoimmune diseases
- Update on EBV specific therapies including adoptive T cell transfer and new vaccine formulations
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 391)
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About this book
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
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Keywords
Table of contents (17 chapters)
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Front Matter
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Lytic EBV Infection
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Front Matter
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Animal Models of EBV Infection
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Front Matter
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Therapy of EBV Associated Diseases
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Epstein Barr Virus Volume 2
Book Subtitle: One Herpes Virus: Many Diseases
Editors: Christian Münz
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-22834-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2015
Hardcover ISBN: 978-3-319-22833-4Published: 14 October 2015
Softcover ISBN: 978-3-319-35834-5Published: 23 August 2016
eBook ISBN: 978-3-319-22834-1Published: 01 October 2015
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VI, 505
Topics: Cancer Research, Immunology, Virology, Infectious Diseases, Animal Models