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Ocular Surface Disease pp 61–79Cite as

Diagnosis and Management of Ocular Involvement in Sjögren’s Syndrome

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Abstract

Evaluation of a patient with dry eye symptoms and possible Sjögren’s syndrome (SS) requires a complete review of systems and a thorough ocular surface examination that includes staining of the conjunctiva. SS patients may have a variety of clinical presentations, and it is important to have a low threshold for referring dry eye patients to a rheumatologist for a SS workup. A stepwise approach to the management of ocular surface disease is advised starting with topical anti-inflammatory therapy, autologous serum tears, and scleral lenses for the more advanced cases. For SS patients undergoing surgery, aggressive ocular surface treatment preoperatively and careful postoperative monitoring is the key to ensuring a successful outcome. In advanced cases of SS with corneal melting or perforation, aggressive local therapy, treatment of the underlying systemic disease with early immunosuppressive therapy, and close collaboration with a rheumatologist are critical to controlling the disease.

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Acknowledgments

Financial Disclosure: Dr. Vivino is a consultant and/or participant in clinical trials for Immco Diagnostics, Inc.

Conflict of Interest: Dr. Vivino is a consultant and/or participant in clinical trials for Immco Diagnostics, Inc.

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Authors and Affiliations

  1. Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, 51 N. 39th Street, Philadelphia, PA, 19104, USA

    Vatinee Y. Bunya MD, Nicole M. Fuerst MD, Stephen E. Orlin MD, Mina Massaro-Giordano MD & Michael E. Sulewski MD

  2. Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, USA

    Frederick B. Vivino MD, MS

Authors
  1. Vatinee Y. Bunya MD
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  2. Nicole M. Fuerst MD
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  3. Stephen E. Orlin MD
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  4. Mina Massaro-Giordano MD
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  5. Frederick B. Vivino MD, MS
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  6. Michael E. Sulewski MD
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Corresponding author

Correspondence to Vatinee Y. Bunya MD .

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Editors and Affiliations

  1. Cornea Service, Illinois Eye and Ear Infirmary, Chicago, Illinois, USA

    Ali R. Djalilian

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Bunya, V.Y., Fuerst, N.M., Orlin, S.E., Massaro-Giordano, M., Vivino, F.B., Sulewski, M.E. (2018). Diagnosis and Management of Ocular Involvement in Sjögren’s Syndrome. In: Djalilian, A. (eds) Ocular Surface Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-15823-5_5

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  • DOI: https://doi.org/10.1007/978-3-319-15823-5_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15822-8

  • Online ISBN: 978-3-319-15823-5

  • eBook Packages: MedicineMedicine (R0)

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