Abstract
Protein binding sites are regions where interactions between a protein and ligand take place. Identification of binding sites is a functional issue especially in structure-based drug design. This paper aims to present a novel feature of protein binding pockets based on the complexity of corresponding weighted Delaunay triangulation. The results demonstrate that candidate binding pockets obtain less relative Von Neumann entropy which means more random scattering of voids inside them.
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Forouzesh, N., Kazemi, M.R., Mohades, A. (2014). Structure-Based Analysis of Protein Binding Pockets Using Von Neumann Entropy. In: Basu, M., Pan, Y., Wang, J. (eds) Bioinformatics Research and Applications. ISBRA 2014. Lecture Notes in Computer Science(), vol 8492. Springer, Cham. https://doi.org/10.1007/978-3-319-08171-7_27
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DOI: https://doi.org/10.1007/978-3-319-08171-7_27
Publisher Name: Springer, Cham
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