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Galanin pp 243–262Cite as

Galanin Systems in Non-mammalian Vertebrates with Special Focus on Fishes

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Part of the book series: Experientia Supplementum ((EXS,volume 102))

Abstract

Galanin is a well characterized multifunctional neuropeptide in mammals. Galanin has been identified from several fishes, amphibians, reptiles and birds. A large set of data is available on galanin-like protein distribution and peptide and/or mRNA sequences in non-mammalian vertebrates. Galanin receptor sequences from fishes and birds are known, but its distribution and mechanisms of actions are poorly understood. While some biological actions of galanin are known in non-mammals, the functional role of galanin in lower vertebrates is limited. For example, galanin has been shown to regulate feeding, pituitary hormone secretion and gut motility in fishes. Several aspects of galanin biology remain unknown, yet, there is enough evidence to implicate galanin as an important physiological modulator in lower vertebrates. Majority of the research articles on galanin in non-mammals arise from studies that used fishes. The objective of this chapter is to provide a summarized discussion of current knowledge on galanin peptide and gene sequences and organization, distribution of galanin gene and protein, and physiological functions of galanin in non-mammalian vertebrates with a special focus on fishes.

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Acknowledgments

Suraj Unniappan (SU) is a Canadian Institutes of Health Research (CIHR) New Investigator and is a recipient of an Early Researcher Award from the Ontario Ministry of Research and Innovation. Research in the laboratory of SU and Helene Volkoff (HV) is supported by research grants from the Natural Sciences and Engineering Research Council (NSERC) of Canada. ETM received a graduate assistantship from York University. Authors dedicate this chapter to the memory of Professor Richard E. Peter, who introduced SU and HV to galanin and to fish neuroendocrinology.

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  1. Laboratory of Integrative Neuroendocrinology, Department of Biology, York University, 4700 Keele Street, Toronto, ON, M3J 1P3, Canada

    Elsie Tachie Mensah & Suraj Unniappan

  2. Department of Biology, Memorial University, St. John’s, NF, A1B 3X9, Canada

    Helene Volkoff

Authors
  1. Elsie Tachie Mensah
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  2. Helene Volkoff
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  3. Suraj Unniappan
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Correspondence to Suraj Unniappan .

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Editors and Affiliations

  1. Dept. Neuroscience, Karolinska Institute, Retzius vaeg 8, Stockholm, 171 77, Sweden

    Tomas Hökfelt

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Mensah, E.T., Volkoff, H., Unniappan, S. (2010). Galanin Systems in Non-mammalian Vertebrates with Special Focus on Fishes. In: Hökfelt, T. (eds) Galanin. Experientia Supplementum, vol 102. Springer, Basel. https://doi.org/10.1007/978-3-0346-0228-0_17

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