Abstract
Continuous glucose monitors (CGMs) have been mainly used in medical applications to monitor blood glucose and to control insulin doses in Type 1 diabetes (T1D) patients. CGMs are becoming popular in people without diabetes and with Type 2 diabetes (T2D) due to their rising commercial availability and effectiveness. They are a useful tool for understanding individuals’ dynamic blood responses to food. However, before such information can be extracted for further analysis, the peaks must be selected automatically. Published works have focused on detecting the onset of meal intakes and calculating their carbohydrate load to assist glucose control in T1D management. This work aims to develop a threshold-based algorithm for entire postprandial peak identification, including starting and endpoints, from data obtained from people with different glucose tolerance levels. The algorithm achieved promising performance using an individual threshold-based approach, with recall and precision rates of 0.84 and 0.85, respectively.
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References
Saeedi, P., et al.: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edn. Diabetes Res. Clin. Pract. 157, 107843 (2019). https://doi.org/10.1016/j.diabres.2019.107843
Sun, H., et al.: The status and trends of diabetes in China: a systematic review and meta-analysis. Diabetes Res. Clin. Pract. 183, 109119 (2022). https://doi.org/10.1016/j.diabres.2021.109119
Gillani, S.W., et al.: Predictors of health-related quality of life among patients with type ii diabetes mellitus who are insulin users: a multidimensional model. Curr. Ther. Res. Clin. Exp. 90, 53–60 (2019). https://doi.org/10.1016/j.curtheres.2019.04.001
Aleppo, G., Webb, K.: Continuous glucose monitoring integration in clinical practice: a stepped guide to data review and interpretation. J. Diabetes Sci. Technol. 13(4), 664–673 (2018). https://doi.org/10.1177/1932296818813581
Beck R.W., Bergenstal R.M.: Continuous glucose monitoring for type 2 diabetes: how does it compare with type 1 diabetes? Diabetes Technol. Ther. 24(3), 153–156 (2022). https://doi.org/10.1089/dia.2021.0374
Ahn, Y.C., et al.: Effectiveness of non-contact dietary coaching in adults with diabetes or prediabetes using a continuous glucose monitoring device: a randomized controlled trial. Healthcare 11(2), 252 (2023). https://doi.org/10.3390/healthcare11020252
Holzer, R., Bloch, W., Brinkmann, C.: Continuous glucose monitoring in healthy adults—possible applications in health care, wellness, and sports. Sensors 22(5), 2030 (2022). https://doi.org/10.3390/s22052030
Fico, G., et al.: Exploring the frequency domain of continuous glucose monitoring signals to improve characterization of glucose variability and of diabetic profiles. J. Diabetes Sci. Technol. 11(4), 773–779 (2017). https://doi.org/10.1177/1932296816685717
Zheng, M., Ni, B., Kleinberg, S.: Discriminating power: a privacy-preserving distributed algorithm for learning decision trees. J. Am. Med. Inform. Assoc. 26(12), 1592–1599 (2019). https://doi.org/10.1093/jamia/ocz159
Samadi, S., et al.: Meal detection and carbohydrate estimation using continuous glucose sensor data. IEEE J. Biomed. Health Inform. 21(3), 619–627 (2017). https://doi.org/10.1109/JBHI.2017.2677953
Daniels, J., Herrero, P., Georgiou, P.: A deep learning framework for automatic meal detection and estimation in artificial pancreas systems. Sensors 22(2), 466 (2022). https://doi.org/10.3390/s22020466.
Faccioli, S., et al.: Super–twisting-based meal detector for type 1 diabetes management: Improvement and assessment in a real-life scenario. Comput. Methods Programs Biomed. 219, 106736 (2022). https://doi.org/10.1016/j.cmpb.2022.106736
Palacios, V., et al.: Machine learning based meal detection using continuous glucose monitoring on healthy participants: an objective measure of participant compliance to protocol. Conf. Proc. IEEE Eng. Med. Biol. Soc. 7032-7035 (2021). https://doi.org/10.1109/EMBC46164.2021.9630408
Eichenlaub, M.M.W.: Mathematical modelling of blood glucose dynamics in normal and impaired glucose tolerance. Ph.D. thesis. University of Warwick (2020)
Zhang, Y., Holt, T.A., Khovanova, N.: A data driven nonlinear stochastic model for bloodglucose dynamics. Comput. Methods Programs Biomed. 125, 18–25 (2016). https://doi.org/10.1016/j.cmpb.2015.10.021
ElSayed N.A., et al.: 6. Glycemic targets: standards of care in diabetes-2023. Diabetes Care 46(Suppl 1), S97–S110 (2023). https://doi.org/10.2337/dc23-S006
Cheng, X., et al.: The shape of the glucose response curve during an oral glucose tolerance test heralds β–cell function in a large Chinese population. BMC. Endocr. Disord. 19(1), 119 (2019). https://doi.org/10.1186/s12902-019-0446-4
Freckmann, G., et al.: Continuous glucose profiles in healthy people with fixed meal times and under everyday life conditions. J. Diabetes Sci. Technol. 19322968221113341 (2022). https://doi.org/10.1177/19322968221113341
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The work is supported by EPSRC (UK) grant (EP/T013648/1) and the University Hospitals Coventry and Warwickshire (UK).
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Archavli, A., Randeva, H., Khovanova, N. (2024). Postprandial Peak Identification from Continuous Glucose Monitoring Time Series. In: Badnjević, A., Gurbeta Pokvić, L. (eds) MEDICON’23 and CMBEBIH’23. MEDICON CMBEBIH 2023 2023. IFMBE Proceedings, vol 93. Springer, Cham. https://doi.org/10.1007/978-3-031-49062-0_11
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