Skip to main content

Postprandial Peak Identification from Continuous Glucose Monitoring Time Series

  • Conference paper
  • First Online:
MEDICON’23 and CMBEBIH’23 (MEDICON 2023, CMBEBIH 2023)

Abstract

Continuous glucose monitors (CGMs) have been mainly used in medical applications to monitor blood glucose and to control insulin doses in Type 1 diabetes (T1D) patients. CGMs are becoming popular in people without diabetes and with Type 2 diabetes (T2D) due to their rising commercial availability and effectiveness. They are a useful tool for understanding individuals’ dynamic blood responses to food. However, before such information can be extracted for further analysis, the peaks must be selected automatically. Published works have focused on detecting the onset of meal intakes and calculating their carbohydrate load to assist glucose control in T1D management. This work aims to develop a threshold-based algorithm for entire postprandial peak identification, including starting and endpoints, from data obtained from people with different glucose tolerance levels. The algorithm achieved promising performance using an individual threshold-based approach, with recall and precision rates of 0.84 and 0.85, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Saeedi, P., et al.: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edn. Diabetes Res. Clin. Pract. 157, 107843 (2019). https://doi.org/10.1016/j.diabres.2019.107843

  2. Sun, H., et al.: The status and trends of diabetes in China: a systematic review and meta-analysis. Diabetes Res. Clin. Pract. 183, 109119 (2022). https://doi.org/10.1016/j.diabres.2021.109119

    Article  Google Scholar 

  3. Gillani, S.W., et al.: Predictors of health-related quality of life among patients with type ii diabetes mellitus who are insulin users: a multidimensional model. Curr. Ther. Res. Clin. Exp. 90, 53–60 (2019). https://doi.org/10.1016/j.curtheres.2019.04.001

  4. Aleppo, G., Webb, K.: Continuous glucose monitoring integration in clinical practice: a stepped guide to data review and interpretation. J. Diabetes Sci. Technol. 13(4), 664–673 (2018). https://doi.org/10.1177/1932296818813581

  5. Beck R.W., Bergenstal R.M.: Continuous glucose monitoring for type 2 diabetes: how does it compare with type 1 diabetes? Diabetes Technol. Ther. 24(3), 153–156 (2022). https://doi.org/10.1089/dia.2021.0374

  6. Ahn, Y.C., et al.: Effectiveness of non-contact dietary coaching in adults with diabetes or prediabetes using a continuous glucose monitoring device: a randomized controlled trial. Healthcare 11(2), 252 (2023). https://doi.org/10.3390/healthcare11020252

    Article  Google Scholar 

  7. Holzer, R., Bloch, W., Brinkmann, C.: Continuous glucose monitoring in healthy adults—possible applications in health care, wellness, and sports. Sensors 22(5), 2030 (2022). https://doi.org/10.3390/s22052030

  8. Fico, G., et al.: Exploring the frequency domain of continuous glucose monitoring signals to improve characterization of glucose variability and of diabetic profiles. J. Diabetes Sci. Technol. 11(4), 773–779 (2017). https://doi.org/10.1177/1932296816685717

  9. Zheng, M., Ni, B., Kleinberg, S.: Discriminating power: a privacy-preserving distributed algorithm for learning decision trees. J. Am. Med. Inform. Assoc. 26(12), 1592–1599 (2019). https://doi.org/10.1093/jamia/ocz159

    Article  Google Scholar 

  10. Samadi, S., et al.: Meal detection and carbohydrate estimation using continuous glucose sensor data. IEEE J. Biomed. Health Inform. 21(3), 619–627 (2017). https://doi.org/10.1109/JBHI.2017.2677953

  11. Daniels, J., Herrero, P., Georgiou, P.: A deep learning framework for automatic meal detection and estimation in artificial pancreas systems. Sensors 22(2), 466 (2022). https://doi.org/10.3390/s22020466.

  12. Faccioli, S., et al.: Super–twisting-based meal detector for type 1 diabetes management: Improvement and assessment in a real-life scenario. Comput. Methods Programs Biomed. 219, 106736 (2022). https://doi.org/10.1016/j.cmpb.2022.106736

  13. Palacios, V., et al.: Machine learning based meal detection using continuous glucose monitoring on healthy participants: an objective measure of participant compliance to protocol. Conf. Proc. IEEE Eng. Med. Biol. Soc. 7032-7035 (2021). https://doi.org/10.1109/EMBC46164.2021.9630408

  14. Eichenlaub, M.M.W.: Mathematical modelling of blood glucose dynamics in normal and impaired glucose tolerance. Ph.D. thesis. University of Warwick (2020)

    Google Scholar 

  15. Zhang, Y., Holt, T.A., Khovanova, N.: A data driven nonlinear stochastic model for bloodglucose dynamics. Comput. Methods Programs Biomed. 125, 18–25 (2016). https://doi.org/10.1016/j.cmpb.2015.10.021

    Article  Google Scholar 

  16. ElSayed N.A., et al.: 6. Glycemic targets: standards of care in diabetes-2023. Diabetes Care 46(Suppl 1), S97–S110 (2023). https://doi.org/10.2337/dc23-S006

  17. Cheng, X., et al.: The shape of the glucose response curve during an oral glucose tolerance test heralds β–cell function in a large Chinese population. BMC. Endocr. Disord. 19(1), 119 (2019). https://doi.org/10.1186/s12902-019-0446-4

    Article  Google Scholar 

  18. Freckmann, G., et al.: Continuous glucose profiles in healthy people with fixed meal times and under everyday life conditions. J. Diabetes Sci. Technol. 19322968221113341 (2022). https://doi.org/10.1177/19322968221113341

Download references

Aknowledgments

The work is supported by EPSRC (UK) grant (EP/T013648/1) and the University Hospitals Coventry and Warwickshire (UK).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Natasha Khovanova .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Archavli, A., Randeva, H., Khovanova, N. (2024). Postprandial Peak Identification from Continuous Glucose Monitoring Time Series. In: Badnjević, A., Gurbeta Pokvić, L. (eds) MEDICON’23 and CMBEBIH’23. MEDICON CMBEBIH 2023 2023. IFMBE Proceedings, vol 93. Springer, Cham. https://doi.org/10.1007/978-3-031-49062-0_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-49062-0_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-49061-3

  • Online ISBN: 978-3-031-49062-0

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics