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Behavioral Neurobiology of GABAB Receptor Function

  • Book
  • © 2022

Overview

Editors:
  1. Styliani Vlachou

    1. School of Psychology Faculty of Science and Health, Dublin City University, Dublin, Ireland

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    You can also search for this editor in PubMed   Google Scholar

  2. Kevin Wickman

    1. Department of Pharmacology, University of Minnesota, Minneapolis, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides readers with a comprehensive perspective on the GABA-B receptor and its therapeutic potential
  • Reflects the state-of-the-art in GABA-B receptor neurobiology through preclinical and clinical research studies
  • Enriches the understanding of the important role of GABA-B receptors in nervous system function and behavior

Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 52)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-vii
    Download chapter PDF

  2. A Brief History and the Significance of the GABAB Receptor

    • Styliani Vlachou
    Pages 1-17

  3. Structural Basis of GABAB Receptor Regulation and Signaling

    • Thorsten Fritzius, Michal Stawarski, Shin Isogai, Bernhard Bettler
    Pages 19-37

  4. Mechanisms and Regulation of Neuronal GABAB Receptor-Dependent Signaling

    • Timothy R. Rose, Kevin Wickman
    Pages 39-79

  5. GABAB Receptor Chemistry and Pharmacology: Agonists, Antagonists, and Allosteric Modulators

    • A. Nieto, T. Bailey, K. Kaczanowska, P. McDonald
    Pages 81-118

  6. GABAB Receptors and Drug Addiction: Psychostimulants and Other Drugs of Abuse

    • Xiaofan Li, Paul A. Slesinger
    Pages 119-155

  7. GABAB Receptors and Alcohol Use Disorders: Preclinical Studies

    • August F. Holtyn, Elise M. Weerts
    Pages 157-194

  8. GABAB Receptors and Alcohol Use Disorders: Clinical Studies

    • Warren B. Logge, Kirsten C. Morley, Paul S. Haber
    Pages 195-212

  9. GABAB Receptors and Pain

    • Dietmar Benke
    Pages 213-239

  10. GABAB Receptors: Anxiety and Mood Disorders

    • Daniela Felice, John F. Cryan, Olivia F. O’Leary
    Pages 241-265

  11. GABAB Receptors in Neurodegeneration

    • Alessandra P. Princivalle
    Pages 267-290

  12. GABAB Receptors and Cognitive Processing in Health and Disease

    • Styliani Vlachou
    Pages 291-329
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Keywords

About this book

It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors.

The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives.

The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.

Editors and Affiliations

  • School of Psychology Faculty of Science and Health, Dublin City University, Dublin, Ireland

    Styliani Vlachou

  • Department of Pharmacology, University of Minnesota, Minneapolis, USA

    Kevin Wickman

Bibliographic Information

  • Book Title: Behavioral Neurobiology of GABAB Receptor Function

  • Editors: Styliani Vlachou, Kevin Wickman

  • Series Title: Current Topics in Behavioral Neurosciences

  • DOI: https://doi.org/10.1007/978-3-030-91335-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-91334-2Published: 21 December 2021

  • Softcover ISBN: 978-3-030-91337-3Published: 22 December 2022

  • eBook ISBN: 978-3-030-91335-9Published: 01 January 2022

  • Series ISSN: 1866-3370

  • Series E-ISSN: 1866-3389

  • Edition Number: 1

  • Number of Pages: VII, 329

  • Number of Illustrations: 55 b/w illustrations, 15 illustrations in colour

  • Topics: Pharmacology/Toxicology, Neurosciences, Psychiatry

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