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Testicular Torsion and Spermatogenesis

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Molecular Mechanisms in Spermatogenesis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1381))

Abstract

Testicular torsion (TT) is a common urologic emergency that can occur at any age. It is most common in newborns and during puberty. Prompt evaluation and management is required to salvage the testis following an episode of torsion. TT brings about damage to testicular tissue and spermatogenesis through various hypothesized mechanisms; however there is a consensus that the effects of ischemia, ischemia-reperfusion injury, and oxidative stress account for the most destructive effects. Numerous studies have examined the effects of various agents and therapies in limiting the effects of TT on the testis.

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Authors and Affiliations

  1. James Buchanan Brady Foundation, Department of Urology, Weill Cornell Medical College of Cornell University, New York, NY, USA

    Omar Al Hussein Alawamlh, Ryan Flannigan, Russell Hayden, Marc Goldstein, Philip S. Li & Richard K. Lee

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  1. Omar Al Hussein Alawamlh
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  2. Ryan Flannigan
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  3. Russell Hayden
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  4. Marc Goldstein
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  6. Richard K. Lee
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Correspondence to Richard K. Lee .

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  1. Sir Run Run Shaw Hospital (SRRSH), Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

    C.Yan Cheng

  2. Sir Run Run Shaw Hospital (SRRSH), Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

    Fei Sun

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Alawamlh, O.A.H., Flannigan, R., Hayden, R., Goldstein, M., Li, P.S., Lee, R.K. (2021). Testicular Torsion and Spermatogenesis. In: Cheng, C., Sun, F. (eds) Molecular Mechanisms in Spermatogenesis. Advances in Experimental Medicine and Biology, vol 1381. Springer, Cham. https://doi.org/10.1007/978-3-030-77779-1_14

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