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Pain Syndromes

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Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

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Abstract

The twentieth century was characterized by great discoveries in medical sciences, which enhanced our knowledge of mechanisms of disease and allowed for the development of pharmacological therapies. During the same period, striking advances were accomplished in the pain field, particularly after the introduction of the concept of pain as a complex phenomenon rather than a simple sensation or a mere symptom. Moreover, at least part of the brain mechanisms related to such a complex experience has been revealed over the last decades with the advance of the neuroimaging field. Nonetheless, adequate pain control, especially in chronic pain patients, is still considered a challenge for clinicians worldwide. In this context, tDCS emerges as a promising mode to provide noninvasive modulation of dysfunctional neural networks present in chronic pain. Indeed, the results of several studies suggest that tDCS can produce long-lasting pain relief in different chronic pain syndromes, including migraine, fibromyalgia, and neuropathic pain. Nevertheless, it is still necessary to establish the most suitable protocols for each chronic pain disorder. Moreover, it is imperative to reveal the neuromechanisms related to tDCS-induced analgesia.

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Authors and Affiliations

  1. Headache & Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA

    Alexandre F. DaSilva

  2. Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

    Marcos Fabio DosSantos

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  1. Alexandre F. DaSilva
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  2. Marcos Fabio DosSantos
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Correspondence to Alexandre F. DaSilva .

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Editors and Affiliations

  1. Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

    André R. Brunoni

  2. Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany

    Michael A. Nitsche

  3. Black Dog Institute & School of Psychiatry, University of New South Wales, Sydney, Australia

    Colleen K. Loo

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DaSilva, A.F., DosSantos, M.F. (2021). Pain Syndromes. In: Brunoni, A.R., Nitsche, M.A., Loo, C.K. (eds) Transcranial Direct Current Stimulation in Neuropsychiatric Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-76136-3_31

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