Abstract
Solitary fibrous tumor (SFT) is an uncommon spindle cell tumor of mesenchymal origin. SFT was first described as a pleural-based mass, but has since been identified in numerous extra-pleural sites including the orbit. Although generally benign, malignant variants have been identified and metastasis can rarely occur [1,2,3]. Ovoid, well-circumscribed, lobulated mass on noncontrast CT that may appear heterogeneous and may contain calcifications. MRI of benign lesions shows heterogeneous iso- to hypointensity on T1w and heterogeneous hypo- to iso-intensity on T2w sequences; hyperintense signal on T1 may suggest recent hemorrhage (methemoglobin). Heterogeneous hyperintensity on T2w sequences raises the possibility of cystic degeneration or hemorrhage. Tubular flow-void signals are occasionally seen, representing intra-tumoral vessels. Marked homogeneous or heterogeneous enhancement following contrast administration may have central cystic or necrotic changes in larger or malignant lesions. Regions of restricted diffusion may be seen [1,2,3,4,5,6,7].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Le CP, Jones S, Valenzuela AA. Orbital solitary fibrous tumor: a case series with review of the literature. Orbit. 2014;33(2):145–51.
Brum M, Nzwalo H, Oliveira E, Pelejão MR, Pereira P, Farias JP, Pimentel J. Solitary fibrous tumors of the orbit and central nervous system: a case series analysis. Asian J Neurosurg. 2018;13(2):336–40.
Blessing NW, Bermudez-Magner JA, Fernandez MP, Rosenberg AE, Dubovy SR, Johnson TE. Solitary fibrous tumor of the orbit: a case series with clinicopathologic correlation and evaluation of STAT6 as a diagnostic marker. Ophthalmic Plast Reconstr Surg. 2020;36(2):164–71.
Shen J, Li H, Feng S, Cui H. Orbital solitary fibrous tumor: a clinicopathologic study from a Chinese tertiary hospital with a literature review. Cancer Manag Res. 2018;10:1069–78.
Yang BT, Wang YZ, Dong JY, Wang XY, Wang ZC. MRI study of solitary fibrous tumor in the orbit. Am J Roentgenol. 2012;199(4):W506–11.
Kim HJ, Kim HJ, Kim YD, Yim YJ, Kim ST, Jeon P, Kim KH, Byun HS, Song HJ. Solitary fibrous tumor of the orbit: CT and MR imaging findings. Am J Neuroradiol. 2008;29(5):857–62.
Liu L, Li KC, Shi H, Tao XF. Solitary fibrous tumours in the extracranial head and neck region: correlation of CT and MR features with pathologic findings. Radiol Med. 2014;119:910–9.
Künzel J, Hainz M, Ziebart T, Pitz S, Ihler F, Strieth S, Matthias C. Head and neck solitary fibrous tumors: a rare and challenging entity. Eur Arch Otorhinolaryngol. 2016;273(6):1589–98.
Smith SC, Gooding WE, Elkins M, Patel RM, Harms PW, McDaniel AS, Palanisamy N, Uram-Tuculescu C, Balzer BB, Lucas DR, Seethala RR, McHugh JB. Solitary fibrous tumors of the head and neck: a multi- institutional clinicopathologic study. Am J Surg Pathol. 2017;41(12):1642–56.
Sayit AT, Elmali M, Gul A, Sullu Y. Solitary fibrous tumor of the orbit: computed tomography and histopathological findings. J Cancer Res Ther. 2019;15(3):719–21. https://doi.org/10.4103/jcrt.JCRT_1194_16.
Ali MJ, et al. Orbital solitary fibrous tumor: a clinicopathologic correlation and review of literature. Oman J Ophthalmol. 2011;4(3):147–9.
Krishnakumar S, Subramanian N, Mohan ER, Mahesh L, Biswas J, Rao NA. Solitary fibrous tumor of the orbit: a clinicopathologic study of six cases with review of the literature. Surv Ophthalmol. 2003;48(5):544–54.
Demura M, Hayashi Y, Sasagawa Y, Mohri M, Takahira M, Nakada M. Intraorbital solitary fibrous tumor requiring preoperative embolization of feeding artery. Asian J Neurosurg. 2019 14(2):593–7.
Chakrabartty H, Singhvi S, Purohit D, Mittal RS. Malignant solitary fibrous tumour of orbit. Asian J Neurosurg. 2017;12(1):55–7.
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this entry
Cite this entry
Ben Cnaan, R., Karlin, J.N., Niry, D., Leibovitch, I., Goldberg, R.A. (2022). Solitary Fibrous Tumor of the Orbit. In: Ben Simon, G., Greenberg, G., Landau Prat, D. (eds) Atlas of Orbital Imaging . Springer, Cham. https://doi.org/10.1007/978-3-030-62426-2_30
Download citation
DOI: https://doi.org/10.1007/978-3-030-62426-2_30
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-62425-5
Online ISBN: 978-3-030-62426-2
eBook Packages: MedicineReference Module Medicine