Abstract
The assessment of olfactory dysfunction (partial or total anosmia) is important in the early diagnosis of neurodegenerative diseases and may be a good indicator in clinical diagnosis. Currently, there is no diagnostic test for partial or total anosmia validated for the Portuguese population. The aim of this study was the development and rheological and sensory characterization of hospital compounded formulations containing 23 different fragrances adapted to Portuguese population. During the studies, several PEG-based formulations were developed. Viscoelasticity assays were performed in the Rheometer Kinexus using the oscillatory method. Differential scanning calorimeter and microscopy were assessed as well as the volatile components analysis by GC-MS. Thus, a new compounding for the diagnosis of olfactive dysfunction with a structured and rheological characteristic adapted to the Portuguese population were developed.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lawton, M., Hu, M.T., Baig, F., et al.: Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin’ Sticks test in patients with Parkinson’s disease. Parkinsonism Relat. Disord. 33, 96–101 (2016)
Ribeiro, H.M., Morais, J.A., Eccleston, G.M.: Structure and rheology of semisolid O/W creams containing cetyl alcohol/non-ionic surfactant mixed emulsifier and different polymers. Int. J. Cosmeti. Sci. 26, 47–59 (2004)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this paper
Cite this paper
Chaves, C., Marto, J., Duarte-Ramos, F., Alcobia, A., Bronze, M.R., Ribeiro, H.M. (2020). Rheological Methods to Evaluate the Efficacy of a New Compounding to Diagnose the Olfactory Dysfunction. In: Galindo-Rosales, F., Campo-Deaño, L., Afonso, A., Alves, M., Pinho, F. (eds) Proceedings of the Iberian Meeting on Rheology (IBEREO 2019). IBEREO 2019. Springer Proceedings in Materials. Springer, Cham. https://doi.org/10.1007/978-3-030-27701-7_6
Download citation
DOI: https://doi.org/10.1007/978-3-030-27701-7_6
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-27700-0
Online ISBN: 978-3-030-27701-7
eBook Packages: EngineeringEngineering (R0)