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Ghrelin Responses to Acute Exercise and Training

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Endocrinology of Physical Activity and Sport

Part of the book series: Contemporary Endocrinology ((COE))

Abstract

Energy homeostasis is regulated by a complex neuroendocrine system including central and peripheral tissues (1, 2). Therefore, the hypothalamus in the brain appears to centrally integrate the various metabolic and hormonal signals, and has an important role in the central responses to changes in energy balance (3). Important in this regulatory system is also the existence of several gut, pancreatic and adipose tissue hormones that communicate the status of body energy stores to the hypothalamus (1). Among the gut hormones secreted in response to nutrient ingestion, ghrelin, peptide YY, cholecystokinin and glucagon-like peptide-1 are involved in regulating both acute and chronic energy homeostasis (4, 5). Therefore, peptide YY, cholecystokinin and glucagon-like peptide-1 function as negative feedback signals, suppressing appetite and food intake once nutrients are ingested (5, 6), and peptide YY has received more attention among appetite and food consumption suppressing peptides (4, 6–9). In contrast, to date, ghrelin remains unique as the only known circulating hormone that stimulates appetite and food consumption (6, 10). This chapter focuses on the available ­information about the effects of acute exercise and chronic training on the secretion of ghrelin.

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  1. Institute of Sport Pedagogy and Coaching Sciences, University of Tartu, Tartu, Estonia

    Jaak Jürimäe PHD & Toivo Jürimäe PHD

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  1. Jaak Jürimäe PHD
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Correspondence to Jaak Jürimäe PHD .

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  1. , Department of Orthopedic Surgery, Hadassah-Hebrew UMC, 4 Ha'razim St, Jerusalem, 91120, Jerusalem, Israel

    Naama Constantini

  2. , Applied Physiology Laboratory, UNC at Chapel Hill, 203 Fezter Hall, Chapel Hill, 27599, North Carolina, USA

    Anthony C. Hackney

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Jürimäe, J., Jürimäe, T. (2013). Ghrelin Responses to Acute Exercise and Training. In: Constantini, N., Hackney, A. (eds) Endocrinology of Physical Activity and Sport. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-314-5_12

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