Overview
- Emphasizes rodent strains that develop autoimmunity such as the NOD mouse, the Akita mouse, and the BB rat
- Features practical, cutting-edge protocols that are ready for the lab
- Includes expert tips and key implementation advice to ensure successful results
- Includes supplementary material: sn.pub/extras
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 933)
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Table of contents (21 protocols)
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Front Matter
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Rodent Models of Type 1 Diabetes
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Front Matter
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Rodent Models of Type 2 Diabetes
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Front Matter
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Other Species
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Front Matter
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General Methodology
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Front Matter
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Keywords
About this book
In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experimentation needed for the invention and testing of novel therapeutic approaches cannot be performed in humans. Thus, there is no alternative to appropriate animal models. In Animal Models in Diabetes Research, expert researchers explore the current status of the most important models and procedures in order to provide a timely resource in experimental diabetology. The first half of the volume serves as a comprehensive overview on our current knowledge of the pathogenesis and pathophysiology of diabetes in animal models through a series of reviews in model strains. The book then continues with vital, established protocols that are employed in the characterization and study of animal models of diabetes. As a volume in the highly successful Methods in Molecular Biology™ series, this work contains the type of detailed description and key implementation advice necessary to achieve successful results.
Authoritative and cutting-edge, Animal Models in Diabetes Research delivers essential content that will be an important resource to advance diabetes research in the years to come.
Editors and Affiliations
Bibliographic Information
Book Title: Animal Models in Diabetes Research
Editors: Hans-Georg Joost, Hadi Al-Hasani, Annette Schürmann
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-068-7
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-62703-067-0Published: 15 August 2012
Softcover ISBN: 978-1-4939-6256-3Published: 23 August 2016
eBook ISBN: 978-1-62703-068-7Published: 15 August 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 325
Topics: Molecular Medicine, Endocrinology