Overview
- Provides the most up-to-date technical information on the new cell culture infection system as written by leading experts in the field
- Presents both an overview and detailed protocols on the replicon system used by virtually all the HCV labs around the world
- Covers a wide range of multi-discipline approaches adopted for HCV research, including NMR-based structure determination and mathematical modelling
- Broadly applicable guides valuable for studying the replication of other positive-strand RNA viruses
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 510)
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About this book
When I was ?rst approached by Dr. Hengli Tang about writing the foreword to this book, the second edition of Hepatitis C Virus, I was a little puzzled: Book forewords are penned by persons far more famous than I am. Surely there were better people to write this, with a handful of the true visionaries in the ?eld immediately coming to my mind. However, after some thought and self-re?ection, I realized that I might just be the right person for the job. I remember the publication of the ?rst edition of Hepatitis C Virus in 1998, the year I began reading about hepatitis C virus with great interest. I purchased a copy of the ?rst edition from my meager graduate student stipend and read it from cover to cover, along with a variety of hepatitis C publications, to try to get a feel if this hepatitis C virus ?eld was something I might want to work on in the future. At the time, the ?rst edition was among the most comprehensive collection of hepatitis C protocols and methods available in one volume. I was amazed at the progress that had been made in hepatitis C research, and even more amazed as I learned more about the experimental challenges facing the ?eld at that time.
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Keywords
Table of contents (33 protocols)
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Front Matter
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HCV Nomenclature, Genotyping, and Quasispecies
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Front Matter
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HCV Replication in Vitro
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Front Matter
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Reviews
From the reviews of the second edition:
“This second edition contains much that was not available for the first edition; replicons, tissue culture infection systems, infectious pseudotype particles, etc. … The chapters are authored by acknowledged experts and are authoritatively written. … Of particular value are the notes sections which highlight practical pitfalls and how to avoid them. Given the size of the hepatitis C community … this book will be a success and should adorn the shelves of many laboratories.” (David J. Rowlands, Microbiology Today, July, 2009)
Editors and Affiliations
Bibliographic Information
Book Title: Hepatitis C
Book Subtitle: Methods and Protocols
Editors: Hengli Tang
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-394-3
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-58829-970-3Published: 10 December 2008
Softcover ISBN: 978-1-61737-859-1Published: 19 November 2010
eBook ISBN: 978-1-59745-394-3Published: 14 November 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: XXII, 466
Number of Illustrations: 73 b/w illustrations, 1 illustrations in colour
Additional Information: Originally published as volume 19 in the series: Methods Molecular Med.
Topics: Hepatology, Infectious Diseases, Virology