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Hepatitis E Virus

Biology, Pathogenesis, Epidemiology, Clinical Description, Diagnosis, and Prevention

  • Chapter
Viral Hepatitis

Abstract

Hepatitis E virus (HEV) is the etiologic agent responsible for the large majority of acute enterically-transmitted non-A hepatitis. While hepatitis E has been documented many times worldwide as major epidemic outbreaks involving thousands of infected individuals with overt disease (1,2), it also accounts for a significant proportion of sporadic hepatitis cases in endemic regions (1,2, see Table 1). The molecular virology and biology of the recently identified HEV, even with its genome completely cloned and sequenced, have not been fully characterized. Current understanding of HEV virus biology, disease manifestations, mode of pathogenesis, its seroepidemiology, and prospects for vaccine intervention will be reviewed in these ensuing sections.

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Authors
  1. Patrice O. Yarbough
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  2. Albert W. Tam
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Editors and Affiliations

  1. Department of Medical Microbiology and Immunology, University of South Florida College of Medicine, Tampa, FL, USA

    Steven Specter

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© 1999 Springer Science+Business Media New York

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Yarbough, P.O., Tam, A.W. (1999). Hepatitis E Virus. In: Specter, S. (eds) Viral Hepatitis. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-702-4_6

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  • DOI: https://doi.org/10.1007/978-1-59259-702-4_6

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-033-5

  • Online ISBN: 978-1-59259-702-4

  • eBook Packages: Springer Book Archive

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