Abstract
The cumulative lifetime risk of developing colorectal cancer for men and women in the United States is about 6% (1). In 2001, colorectal cancer is expected to be the fourth most common cause of cancer, accounting for over 135,000 new cases, and the second most common cause of cancer death, resulting in approx 57,000 deaths, among Americans (1). The detection of early-stage disease at diagnosis is associated with significantly improved survival, with a 5-yr survival rate of greater than 90% for those with localized disease (2).
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References
Greenlee RT, Hill-Harmon MB, Murray T, et al. Cancer Statistics, 2001. CA: Cancer J. Clin., 51 (2001) 15–36.
Ries LAG, Kosary CL, Hankey BF, Miller BA, and Edwards BK (eds.). SEER Cancer Statistics, 1973–1995. National Cancer Institute, Bethesda, MD, 1998.
Winawer SJ, Zauber AG, Ho MN, et al. Prevention of colorectal cancer by colonoscopic polypectomy. N. Engl. J. Med., 329 (1993) 1977–1981.
Stryker SJ, Wolff BG, Culp CE, et al. Natural history of untreated colonic polyps. Gastroenterology, 93 (1987) 1009–1013.
Atkin WS, Morson BC, and Cuzick J. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. N. Engl. J. Med., 326 (1992) 658–662.
Gloeckler-Ries LA, Hankey BF, and Edwards BK (eds.). Cancer Statistics Review, 1973–1987. Department of Health and Human Services, Bethesda, MD, DHHS publication no. (NIH) 90–2789, 1990.
Mandel JS, Bond JH, Church TR, et al. Reducing mortality from colorectal cancer by screening for fecal occult blood. N. Engl. J. Med., 328 (1993) 1365–1371.
Hardcastle JD, Chamberlain JO, Robinson MHE, et al. Randomised controlled trial of faecal-occult-blood screening for colorectal cancer. Lancet, 348, 1472–1477.
Kronborg O, Fenger C, Olsen J, et al. Randomised study of screening for colorectal cancer with faecaloccult-blood test. Lancet, 348 (1996) 1467–1471.
Winawer SJ, Flehinger BJ, Schottenfeld D, et al. Screening for colorectal cancer with fecal occult blood testing and sigmoidoscopy. J. Natl. Cancer Inst., 85 (1993) 1311–1318.
Selby JV, Friedman GD, Quesenberry CP, et al. Effect of fecal occult blood testing on mortality from colorectal cancer: a case-control study. Ann. Intern. Med., 118 (1993) 1–6.
Wahrendorf J, Robra B-P, Wiebelt H, et al. Effectiveness of colorectal cancer screening: results from a population-based case-control evaluation in Saarland, Germany Eur. J. Cancer Prev., 2 (1993) 221–227.
Mandel JS, Church TR, Bond JH, et al. The effect of fecal occult-blood screening on the incidence of colorectal cancer. N. Engl. J. Med., 343 (2000) 1603–1607.
Selby JV, Friedman GD, Quesenberry CP, et al. A case-control study of screening sigmoidoscopy and mortality from colorectal cancer. N. Engl. J. Med., 326 (1992) 653–657.
Newcomb PA, Norfleet RG, Storer BE, et al. Screening sigmoidoscopy and colorectal cancer mortality. J. Natl. Cancer Inst., 84 (1992) 1572–1575.
Gohagen JK, Prorok PC, Kramer BS, et al. The prostate, lung, colorectal, and ovarian cancer screening trial of the National Cancer Institute. Cancer, 75 (1995) 1869–1873.
Atkin WS, Hart A, Edwards R, et al. Uptake, yield of neoplasia, and adverse effects of flexible sigmoidoscopy screening. Gut, 42 (1998) 560–565.
Winawer SJ, Fletcher RH, Miller L, et al. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology, 112 (1997) 594–642.
Rex DK, Johnson DA, Lieberman DA, et al. Colorectal cancer prevention 2000: screening recommendations of the American College of Gastroenterology. Am. J. Gastroenterol., 95 (2000) 868–877.
Smith RA, von Eschenbach AC, Wender R, et al. American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers and update 2001: testing for early lung cancer detection. CA: Cancer J. Clin., 51 (2001) 38–75.
Lieberman DA, Weiss DG, Bond J, et al. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. N. Engl. J. Med., 343 (2000) 162–168.
Imperiale TF, Wagner DR, Lin CY, et al. Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings. N. Engl. J. Med., 343 (2000) 169–174.
Fork FT. Double contrast enema and colonoscopy in polyp detection. Gut, 22 (1981) 971–977.
Hixson LJ, Fennerty MB, Sampliner RE, et al. Prospective study of the frequency and size distribution of polyps missed by colonoscopy. J. Natl. Cancer Inst., 82 (1990) 1769–1772.
Hixson LJ, Fennerty MB, Sampliner RE, et al. Prospective blinded trial of the colonoscopic miss-rate of large colorectal polyps. Gastrointest. Endoscopy, 37 (1991) 125–127.
Steine S, Stordahl A, Lunde OC, et al. Double-contrast barium enema versus colonoscopy in the diagnosis of neoplastic disorders: aspects of decision-making in general practice. Fam. Pract., 10 (1993) 288–291.
Jaramillo E and Slezak P. Comparison between double-contrast barium enema and colonoscopy to investigate lower gastrointestinal bleeding. Gastrointest. Radiol., 17 (1992) 81–83.
Jensen J, Kewenter J, Asztely M, et al. Double contrast barium enema and flexible rectosigmoidoscopy: a reliable diagnostic combination for detection of colorectal neoplasm. Br. J. Surg., 77 (1990) 270–272.
O’Brien MJ, Winawer SJ, Zauber AG, et al. The National Polyp Study: patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology, 98 (1990) 371–379.
Shinya H and Wolff WI. Morphology, anatomic distribution and cancer potential of colonic polyps: an analysis of 7,000 polyps endoscopically removed. Ann. Surg., 190 (1979) 679–683.
Winawer SJ, Zauber AG, O’Brien MJ, et al. The National Polyp Study: design, methods, and characteristics of patients with newly diagnosed polyps. Cancer, 70 (1992) 1236–1245.
Rickert RR, Auerbach O, Garfinkel L, et al. Adenomatous lesions of the large bowel: an autopsy study. Cancer, 43 (1979) 1847–1857.
The National Polyp Study Workgroup, Winawer SJ, Zauber A, Diaz B. The National Polyp Study: temporal sequence of evolving colorectal cancer from the normal colon. Gastrointest. Endoscopy, 33 (1987) 167.
Muto T, Bussey HJR, and Morson BC. The evolution of cancer of the colon and rectum. Cancer, 36 (1975) 2251–2270.
Vasen HFA, Nagengast FM, and Meera Khan P. Interval cancers in hereditary non-polyposis colorectal cancer (Lynch syndrome). Lancet, 345 (1995) 1183–1184.
Markowitz AJ, Winawer SJ, Zauber AG, et al. Rapid appearance of colorectal cancer following negative colonoscopy in HNPCC. Gastroenterology, 116 (1999) A458 (abstract).
Burt RW and Petersen GM. Familial colorectal cancer: diagnosis and management. In Prevention and Early Detection of Colorectal Cancer. Young GP, Rozen P, Levin B (eds.), WB Saunders, London, 1996, pp. 171–194.
Winawer SJ, Zauber AG, Gerdes H, et al. Risk of colorectal cancer in the families of patients with adenomatous polyps. N. Engl. J. Med., 334 (1996) 82–87.
Sachar DB. Cancer in inflammatory bowel disease. In Inflammatory Bowel Disease-Basic Research and Clinical Implications. Goebell H, Peskan BM, and Malchow H, (eds.), MTP Press, Boston, 1988, pp. 289–294.
Butt JH and Lennard-Jones JE. A practical approach to the cancer risk in inflammatory bowel disease. Med. Clin. North Am., 64 (1980) 1203–1220.
Johnson W, McDermott F, Hughes E, et al. Carcinoma of the colon and rectum in inflammatory disease of the intestine. Surg. Gynecol. Obstet., 156 (1983) 193–197.
Gyde SN, Prior P, Allan PN, et al. Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centers. Gut, 29 (1988) 206–217.
Katzka I, Brody R, Morris E, et al. Assessment of colorectal cancer risk in patients with ulcerative colitis: experience from a private practice. Gastroenterology, 85 (1983) 22–29.
Lennard-Jones JE, Melville DM, Morson BC, et al. Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years. Gut, 31 (1990) 800–806.
Brostrom O, Lofberg R, Nordenvall B, et al. The risk of colorectal cancer in ulcerative colitis: an epidemiologic study. Scand. J. Gastroenterol., 221 (1987) 1193–1199.
Gilat T, Fireman Z, Grossman A, et al. Colorectal cancer in patients with ulcerative colitis: a population study in central Israel. Gastroenterology, 94 (1988) 870–877.
Ransohoff DF. Colon cancer in ulcerative colitis. Gastroenterology, 94 (1988) 1089–1091.
Lennard-Jones JE. Cancer risk in ulcerative colitis: surveillance of surgery. Br. J. Surg., 72 (1985) 584–586.
MacDougall IPM. Cancer risk in ulcerative colitis. Lancet, 2 (1964) 655–658.
Greenstein A, Sachar D, Smith H, et al. Cancer in universal and left-sided ulcerative colitis: factors determining risk. Gastroenterology, 77 (1979) 290–294.
Waye JD. Screening for cancer in ulcerative colitis. Front. Gastrointest. Res., 10 (1986) 243–256.
Choi PM, Nugent FW, Schoetz DJ, et al. Colonoscopic surveillance reduces mortality from colorectal cancer in ulcerative colitis. Gastroenterology, 105 (1993) 418–424.
Greenstein AJ, Sachar DB, Smith H, et al. A comparison of cancer risk in Crohn’s disease and ulcerative colitis. Cancer, 48 (1981) 2742–2745.
Ekbom A, Helmick C, Zack M, et al. Increased risk of large bowel cancer in Crohn’s disease with colonic involvement. Lancet, 336 (1990) 357–359.
Sachar DB. Cancer in Crohn’s disease: dispelling the myths. Gut, 35 (1994) 1507–1508.
Moertel CG, Bargen JA, and Dockerty MB. Multiple carcinomas of the large intestine: a review of the literature and a study of 261 cases. Gastroenterology, 34 (1958) 85–98.
Nava HR and Pagana TJ. Postoperative surveillance of colorectal carcinoma. Cancer, 49 (1982) 1043–1047.
Howard ML and Greene FL. The effect of preoperative endoscopy on recurrence and survival following surgery for colorectal carcinoma. Am. Surg., 56 (1990) 124–127.
Brahme F, Ekelund G, Norden JG, et al. Metachronous colorectal polyps: comparison of development of colorectal polyps and carcinomas with and without history of polyps. Dis. Colon Rectum, 17 (1974) 166–171.
Bodmer WF, Bailey CJ, Bodmer J, et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature, 328 (1987) 614–616.
Leppert M, Dobbs M, and Scambler P. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science, 238 (1987) 1411–1413.
Kinzler KW, Nilbert MC, Su Li-Kuo, et al. Identification of FAP locus genes from chromosome 5q21. Science, 253 (1991) 661–665.
Groden J, Thliveris A, Samowitz W, et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell, 66 (1991) 589–600.
Jeghers H, McKusick VA, and Katz KH. Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits: a syndrome of diagnostic significance. N. Engl. J. Med., 241 (1949) 993–1005.
Jenne DE, Reimann H, Nezu J, et al. Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nature Genet., 18 (1998) 38–43.
Hemminki A, Markie D, Tomlinson I, et al. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature, 391 (1998) 184–187.
Giardiello FM, Welsh SB, Hamilton SR, et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N. Engl. J. Med., 316 (1987) 1511–1514.
Spigelman AD, Murday V, and Phillips RKS. Cancer and the Peutz-Jeghers syndrome. Gut, 30 (1989) 1588–1590.
Watanabe A, Nagashima H, Motoi M, and Ogawa K. Familial juvenile polyposis of the stomach. Gastroenterology, 77 (1979) 148–151.
Grotsky HW, Rickert RR, Smith WD, and Newsome JE Familial juvenile polyposis coli: a clinical and pathologic study of a large kindred. Gastroenterology, 82 (1982) 494–501.
Sachatello CR, Pickren JW, and Grace JT Jr. Generalized juvenile gastrointestinal polyposis: a hereditary syndrome. Gastroenterology, 58 (1970) 699–708.
Haggitt RC and Reid BJ. Hereditary gastrointestinal polyposis syndromes. Am. J. Surg. Pathol., 10 (1986) 871–887.
Jarvinen H and Franssila KO. Familial juvenile polyposis coli: increased risk of colorectal cancer. Gut, 25 (1984) 792–800.
Vasen HF, Mecklin JP, Khan PM, et al. The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC). Dis. Colon Rectum, 34 (1991) 424–425.
Watson P and Lynch HT. Extracolonic cancer in Hereditary Nonpolyposis Colorectal Cancer. Cancer, 71 (1993) 677–685.
Vasen HFA, Watson P, Mecklin JP, et al. New clinical criteria for hereditary non-polyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology, 116 (1999) 1453–1456.
Peltosmaki P, Aaltonen LA, Sistonen P, et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science, 260 (1992) 810–812.
Fishel R, Lescoe MK, Rao MRS, et al. The human mutator gene homolog, MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75 (1993) 1027–1038.
Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a muts homolog in hereditary nonpolyposis colorectal cancer. Cell, 75 (1993) 1215–1235.
Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary nonpolyposis colon cancer. Nature, 368 (1994) 258–261.
Akiyama Y, Sato H, Yamada T, et al. Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res., 57 (1997) 3920–3923.
Jarvinen HJ, Mecklin JP, and Sistonen P. Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer. Gastroenterology, 108 (1995) 1405–1411.
Breite I, Markowitz A, Zauber A, et al. Colonoscopy screening of patients at high familial risk for colorectal cancer. Gastroenterology, 110 (1996) 495 (abstract).
Bond JH. Polyp guideline: diagnosis, treatment, and surveillance for patients with colorectal polyps. Practice Parameters Committee of the American College of Gastroenterology. Am. J. Gastroenterol., 95 (2000) 3053–3063.
Winawer SJ, Zauber AG, O’Brien MJ, et al. Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. N. Engl. J. Med., 328 (1993) 901–906.
Zauber AG, Winawer SJ, Bond JH, et al. Can surveillance intervals be lengthened following colonoscopic polypectomy? Gastroenterology, 112 (1997) A50 (abstract).
Zauber AG, Bond JH, and Winawer SJ. Surveillance of patients with colorectal adenomas or cancer. In Prevention and Early Detection of Colorectal Cancer. Young GP, Rozen P, and Levin B (eds.), WB Saunders, London, 1996, pp. 195–215.
Wagner JL, Tunis S, Brown M, et al. The cost effectiveness of colorectal cancer screening in average-risk adults. In Prevention and Early Detection of Colorectal Cancer. Young G and Levin B (eds.), WB Saunders, New York, 1996.
Eddy DM, Nugent FW, Eddy JF, et al. Screening for colorectal cancer in a high-risk population: results of a mathematical model. Gastroenterology, 92 (1987) 682–692.
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Markowitz, A.J. (2002). Screening and Surveillance. In: Saltz, L.B. (eds) Colorectal Cancer. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-160-2_4
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DOI: https://doi.org/10.1007/978-1-59259-160-2_4
Publisher Name: Humana Press, Totowa, NJ
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