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Streptomyces coelicolor

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Bacteria, Bacteriophages, and Fungi

Abstract

Three features of Streptomycetes formed the initial stimulus for making genetic studies of them: their taxonomic distance from the genetically well-studied Gram-negative bacteria, their morphological complexity, unique among prokaryotes and perhaps of general interest in the study of morphogenesis (Chater and Hopwood, 1973), and their role as major industrial producers of antibiotics. The hundred or so genetic markers that have been identified in the most-studied strain, Streptomyces coelicolor A3(2) (Streptomyces violaceoruber according to Kutzner and Waksman, 1959) have all turned out to be located on a single circular linkage map (see Figure 1) in a curiously symmetrical arrangement (Hopwood, 1967), and a unique fertility system governing various aspects of recombinant formation has become apparent (Hopwood et al., 1969; Vivian and Hopwood, 1970, 1973; Vivian, 1971; Hopwood and Wright, 1973). These novel features make S. coelicolor an organism of considerable importance in comparative bacterial genetics.

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Literature Cited

  • Alikhanian, S. I., T. S. Iljina and N. D. Lomovskaya, 1960 Transduction in actinomyces. Nature (Lond.) 188:245–246.

    Article  CAS  Google Scholar 

  • Boyer, H. W., 1971 DNA restriction and modification mechanisms in bacteria. Annu. Reu. Microbiol. 25:153–176.

    Article  CAS  Google Scholar 

  • Chater, K. F., 1972 A morphological and genetic mapping study of white colony mutants of Streptomyces coelicolor. J. Gen. Microbiol. 72:9–28.

    Article  PubMed  CAS  Google Scholar 

  • Chater, K. F., 1974 Rifampicin resistant mutants of Streptomyces coelicolor A3(2). J. Gen. Microbiol. 80:277–290.

    Article  PubMed  CAS  Google Scholar 

  • Chater, K. F. and D. A. Hopwood, 1973 Differentiation in actinomycetes. In Microbial Differentiation, 23rd Symposium of the Society for General Microbiology, edited by J. M. Ashworth and J. E. Smith, pp. 143–160, Cambridge University Press, Cambridge, England.

    Google Scholar 

  • Danford, T. R. and J. I. Frea, 1970 Protoplasts in actinomycetes. Bacteriol. Proc: 37-38.

    Google Scholar 

  • Delic, V., D. A. Hopwood and E. J. Friend, 1970 Mutagenesis by N-methyl-N′-nitro-N-nitrosoguanidine (NTG) in Streptomyces coelicolor. Mutat. Res. 9:167–182.

    Article  PubMed  CAS  Google Scholar 

  • Dowding, J. E., 1973 Characterization of a bacteriophage virulent for Streptomyces coelicolor A3(2). J. Gen. Microbiol. 76:163–176.

    Article  PubMed  CAS  Google Scholar 

  • Dowding, J. E. and D. A. Hopwood, 1973 Temperate bacteriophages for Streptomyces coelicolor A3(2) isolated from soil. J. Gen. Microbiol. 78:349–359.

    Article  Google Scholar 

  • Engel, P. E., 1970 Genetic control of tryptophan biosynthesis in Streptomyces coelicolor. In Genetics of Industrial Microorganisms: Actinomycetes and Fungi, edited by Z. VanÄ›k, Z. HoÅ¡tálek and J. Cudlin, pp. 125–147, Academia, Prague.

    Google Scholar 

  • Friend, E. J. and D. A. Hopwood, 1971 The linkage map of Streptomyces rimosus. J. Gen. Microbiol. 68:187–197.

    Article  PubMed  CAS  Google Scholar 

  • Harold, R. J. and D. A. Hopwood, 1970a Ultraviolet-sensitive mutants of Streptomyces coelicolor. I. Phenotypic characterisation. Mutat. Res. 10:427–438.

    Article  PubMed  CAS  Google Scholar 

  • Harold, R. J. and D. A. Hopwood, 1970b Ultraviolet-sensitive mutants of Streptomyces coelicolor. II. Genetics. Mutat. Res. 10:439–448.

    Article  PubMed  CAS  Google Scholar 

  • Harold, R. J. and D. A. Hopwood, 1972 A rapid method for complementation testing of ultraviolet-sensitive (uvs) mutants of Streptomyces coelicolor. Mutat. Res. 16:27–34.

    Article  PubMed  CAS  Google Scholar 

  • Hopwood, D. A., 1959 Linkage and the mechanism of recombination in Streptomyces coelicolor. Ann. N. Y. Acad. Sci. 81:887–898.

    Article  PubMed  CAS  Google Scholar 

  • Hopwood, D. A., 1965 New data on the linkage map of Streptomyces coelicolor. Genet. Res. 6:248–262.

    Article  CAS  Google Scholar 

  • Hopwood, D. A., 1966a Non-random location of temperature-sensitive mutants on the linkage map of Streptomyces coelicolor. Genetics 54:1169–1176.

    PubMed  CAS  Google Scholar 

  • Hopwood, D. A., 1966b Lack of constant genome ends in Streptomyces coelicolor. Genetics 54:1177–1184.

    PubMed  CAS  Google Scholar 

  • Hopwood, D. A., 1967 Genetic analysis and genome structure in Streptomyces coelicolor. Bacteriol. Rev. 31:373–403.

    PubMed  CAS  Google Scholar 

  • Hopwood, D. A., 1970a The isolation of mutants. In Methods in Microbiology, Vol. 3A, edited by J. R. Norris and D. W. Ribbons, pp. 363–433, Academic Press, London.

    Google Scholar 

  • Hopwood, D. A., 1970b Developments in actinomycete genetics. In Genetics of Industrial Microorganisms: Actinomycetes and Fungi, edited by Z. VanÄ›k, Z. HoÅ¡tálek and J. Cudlín, pp. 21–46, Academia, Prague.

    Google Scholar 

  • Hopwood, D. A., 1972a Genetic analysis in microorganisms. In Methods in Microbiology, Vol. 7B, edited by J. R. Norris and D. W. Ribbons, pp. 29–158, Academic Press, London.

    Google Scholar 

  • Hopwood, D. A., 1972b Genetics of the actinomycetales. In Actinomycetales: Characteristics and Practical Importance, edited by G. Sykes and F. A. Skinner, pp. 131–153, Academic Press, London.

    Google Scholar 

  • Hopwood, D. A. and H. M. Ferguson, 1970 A rapid method for lyophilizing Streptomyces cultures. J. Appl. Bacteriol. 32:434–436.

    Google Scholar 

  • Hopwood, D. A. and G. Sermonti, 1962 The genetics of Streptomyces coelicolor. Adv. Genet. 11:273–342.

    Article  Google Scholar 

  • Hopwood, D. A. and H. M. Wright, 1973 A plasmid of Streptomyces coelicolor carrying a chromosomal locus and its interspecific transfer. J. Gen. Microbiol. 79:331–342.

    Article  PubMed  CAS  Google Scholar 

  • Hopwood, D. A., G. Sermonti and I. Spada-Sermonti, 1963 Heterozygous clones in Streptomyces coelicolor. J. Gen. Microbiol. 30:249–260.

    Article  PubMed  CAS  Google Scholar 

  • Hopwood, D. A., R. J. Harold, A. Vivian and H. M. Ferguson, 1969 A new kind of fertility variant in Streptomyces coelicolor. Genetics 62:461–477.

    PubMed  CAS  Google Scholar 

  • Hopwood, D. A., H. Wildermuth and H. M. Palmer, 1970 Mutants of Streptomyces coelicolor defective in sporulation. J. Gen. Microbiol. 61:397–408.

    Article  PubMed  CAS  Google Scholar 

  • Hopwood, D. A., K. F. Chater, J. E. Dowding and A. Vivian, 1973 Advances in Streptomyces coelicolor genetics. Bacteriol. Rev. 37:371–405.

    PubMed  CAS  Google Scholar 

  • Kutzner H. J. and S. A. Waksman, 1959 Streptomyces coelicolor Müller and Strep-tomyces violaceoruber Waksman and Curtis, two distinctly different organisms. J. Bacteriol. 78:528–538.

    PubMed  CAS  Google Scholar 

  • Lomovskaya, N. D., L. K. Emeljanova and S. I. Alikhanian, 1971 The genetic location of prophage on the chromosome of Streptomyces coelicolor. Genetics 68:341–347.

    PubMed  CAS  Google Scholar 

  • Lomovskaya, N. D., N. M. Mkrtumian, N. L. Gostimskaya and V. N. Danilenko, 1972 Characterization of temperate actinophage φC31 isolated from Streptomyces coelicolor A3(2). J. Virol 9:258–262.

    PubMed  CAS  Google Scholar 

  • Lomovskaya, N. D., L. K. Emeljanova, N. M. Mkrtumian and S. I. Alikhanian, 1973 The prophage behavior in crosses between lysogenic and nonlysogenic derivatives of Streptomyces coelicolor A3(2).J. Gen. Microbiol. 77:455–463.

    Article  PubMed  CAS  Google Scholar 

  • Marmur, J., 1961 A procedure for the isolation of deoxyribonucleic acid from microorganisms. J. Mol. Biol. 3:208–218.

    Article  CAS  Google Scholar 

  • Randazzo, R., G. Sermonti, A. Carere and M. Bignomi, 1973 Comutation in Streptomyces. J. Bacteriol. 113:500–501.

    PubMed  CAS  Google Scholar 

  • Russi, S., A. Carere, B. Fratello and V. Khoudokormoff, 1966 Caratterizzazione biochimica di alcuni mutanti di Streptomyces coelicolor richiedenti istidina. Ann. Ist. Super. Sanità 2:506–522.

    PubMed  CAS  Google Scholar 

  • Scott, B. R. and T. Alderson, 1971 The random (non-specific) forward mutational response of gene loci in Aspergillus conidia after photosensitization to near ultraviolet light (365 mm) by 8-methoxypsoralen. Mutat. Res. 12:29–34.

    Article  PubMed  CAS  Google Scholar 

  • Sermonti, G., 1969 Genetics of Antibiotic-Producing Microorganisms, Wiley-Interscience, London.

    Google Scholar 

  • Sermonti, G., A. Mancinelli and I. Spada-Sermonti, 1960 Heterogenous clones (heteroclones) in Streptomyces coelicolor A3(2). Genetics 45:669–672.

    PubMed  CAS  Google Scholar 

  • Sermonti, G., A. M. Puglia and G. Ficarra, 1971 The time course of recombinant production in Streptomyces coelicolor. Genet. Res. 18:133–145.

    Article  PubMed  CAS  Google Scholar 

  • Townsend, M. E., H. M. Wright and D. A. Hopwood, 1971 Efficient mutagenesis by near ultraviolet light in the presence of 8-methoxypsoralen in Streptomyces. J. Appl. Bacteriol. 34:799–801.

    Article  PubMed  CAS  Google Scholar 

  • Vivian, A., 1971 Genetic control of fertility in Streptomyces coelicolor A3(2): plasmid involvement in the interconversion of UF and IF strains. J. Gen. Microbiol. 69:353–364.

    Article  Google Scholar 

  • Vivian, A. and D. A. Hopwood, 1970 Genetic control of fertility in Streptomyces coelicolor A3(2): the IF fertility type. J. Gen. Microbiol. 64:101–117.

    Article  PubMed  CAS  Google Scholar 

  • Vivian, A. and D. A. Hopwood, 1973 Genetic control of fertility in Streptomyces coelicolor A3(2): new kinds of donor strains. J. Gen. Microbiol. 76:147–162.

    Article  Google Scholar 

  • Welsch, M., 1969 Biology of actinophages In Symposium on Genetics and Breeding of Streptomyces, Dubrovnik, pp. 43-62, Yugoslav Academy of Sciences and Arts, Zagreb.

    Google Scholar 

  • Wildermuth, H., 1970 Development and organization of the aerial mycelium in Streptomyces coelicolor. J. Gen. Microbiol. 60:43–50.

    Article  PubMed  CAS  Google Scholar 

  • Wildermuth, H. and D. A. Hopwood, 1970 Septation during sporulation in Streptomyces coelicolor. J. Gen. Microbiol. 60:51–59.

    Article  PubMed  CAS  Google Scholar 

  • Wilcockson, J., 1973 The use of sodium perchlorate in deproteinization during the preparation of nucleic acids. Biochem. J. 135:561–599.

    Google Scholar 

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Author information

Authors and Affiliations

  1. John Innes Institute, Norwich, England

    David A. Hopwood & Keith F. Chater

Authors
  1. David A. Hopwood
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  2. Keith F. Chater
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Editor information

Editors and Affiliations

  1. Department of Biological Sciences, Northwestern University, Evanston, Illinois, USA

    Robert C. King (Professor of Genetics) (Professor of Genetics)

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Hopwood, D.A., Chater, K.F. (1974). Streptomyces coelicolor. In: King, R.C. (eds) Bacteria, Bacteriophages, and Fungi. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1710-2_15

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  • DOI: https://doi.org/10.1007/978-1-4899-1710-2_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1712-6

  • Online ISBN: 978-1-4899-1710-2

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